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New report shows 6.6 million children under 5 died in 2012

In 2012, approximately 6.6 million children worldwide - 18 000 children per day - died before reaching their fifth birthday, according to a new report released today by UNICEF, WHO, the World Bank Group and the United Nations Department of Economic and Social Affairs/Population Division. This is roughly half the number of under-fives who died in 1990, when more than 12 million children died.

13 Sep 2013

Undervaccination results in increased risk for whooping cough in young children

Undervaccination – not receiving all recommended vaccinations or not being vaccinated according to the Advisory Committee on Immunization Practices schedule – results in an increased risk for whooping cough in children 3 to 36 months of age, according to a new Kaiser Permanente study.

12 Sep 2013

State highlights: Texas Gov. Perry touts tort reform; Calif. lawmakers want to pass 100 bills per day

A measles outbreak in a vaccination-wary North Texas megachurch and soaring rates of whooping cough across the state are drawing renewed calls for immunization legislation, which some lawmakers and medical professionals argue would help the state prevent public health crises (Aaronson, 9/10).

11 Sep 2013

Unique mobile app allows parents to access information about safety of vaccines

The Vaccine Education Center at The Children's Hospital of Philadelphia is launching Vaccines on the Go: What You Should Know, a unique mobile app that allows busy parents to access up-to-date, reliable information about the science and safety of vaccines -- wherever and whenever they need it.

11 Sep 2013

2D Barcoding of U.S. vaccines: an interview with Dr. Leonard Friedland, VP, Director, Scientific Affairs and Public Health, GSK Vaccines North America

2D barcodes contain product identification, lot number, and expiration date. Linear barcodes only contain product identification information.

10 Sep 2013

First Edition: September 10, 2013

Today's headlines include reports from Capitol Hill about the GOP strategy to link debate of a stopgap spending bill to keep the government operating to efforts to defund the health law.

10 Sep 2013

Roche, Inovio Pharmaceuticals to develop DNA-based vaccines for prostate cancer and hepatitis B

Roche and Inovio Pharmaceuticals, Inc. announced today that they have entered into an exclusive worldwide license agreement to research, develop and commercialize Inovio's highly-optimized, multi-antigen DNA immunotherapies targeting prostate cancer and hepatitis B.

10 Sep 2013

Safety and health checklist to help kids avoid emergency room

With the school year underway, Children's Hospital Los Angeles experts have developed a safety and health checklist to help kids avoid the emergency room and develop productive extracurricular and learning activities to enhance the classroom experience. What do parents need to consider? Many symptoms of childhood conditions are often discovered in the classroom.

7 Sep 2013

Study finds similar antibody levels among 4 PCV13 immunization schedules

The use of 4 different 13-valent pneumococcal conjugate vaccine immunization schedules in healthy term infants resulted in no statistically significant differences in antibody levels between the infants after the booster dose at 12 months of age for almost all serotypes, according to a study in the September 4 issue of JAMA.

5 Sep 2013

New influenza vaccine delivered via microneedle avoids pain and side effects

Scientists have developed an influenza vaccine delivered via microneedle patch that provided 100 percent protection against a lethal influenza virus in mice more than one year after vaccination. They report their findings in the September 2013 issue of the journal Clinical and Vaccine Immunology.

5 Sep 2013

Taiwan's HBV immunization program for newborns lowers chronic HBV carriers, incidence of HCC

"Hepatitis B virus infection causes infant fulminant hepatitis, and chronic HBV infection may progress to chronic liver disease and hepatocellular carcinoma. Taiwan launched a nationwide HBV immunization program for newborns in July 1984, which has successfully lowered the prevalence of chronic HBV carriers, incidence of HCC, and mortality of IFH in vaccinated birth cohorts. The mortality of CLD before and after HBV immunization has never been examined," write Chun-Ju Chiang, Ph.D., of National Taiwan University, Taipei, and colleagues.

4 Sep 2013

New recombinant antibody can recognize MSCs in umbilical cord blood

A new recombinant antibody can detect and isolate mesenchymal stem cells (MSCs), a nonembryonic source of stem cells with promising applications in tissue engineering, blood stem cell transplantation, and treatments for immune-mediated disorders.

4 Sep 2013

Infant rotavirus vaccination reduced severe gastroenteritis among U.S. children

"Implementation of infant rotavirus vaccination in 2006 has substantially reduced the burden of severe gastroenteritis among U.S. children younger than 5 years," write Paul A. Gastanaduy, M.D., M.P.H., of the Centers for Disease Control and Prevention, Atlanta, and colleagues. "Whether indirect protection (due to reduced transmission of rotavirus) extends to adults remains unclear."

28 Aug 2013

Sanofi Pasteur reports clinical benefit of Fluzone High-Dose vaccine in preventing influenza

Sanofi Pasteur, the vaccines division of Sanofi, today announced topline results of a large-scale, multi-center efficacy trial in people 65 years of age and older showing a superior clinical benefit of Fluzone High-Dose (Influenza Virus Vaccine) relative to the standard dose of Fluzone vaccine in preventing influenza.

26 Aug 2013

Novartis starts shipment of 2013-2014 seasonal influenza vaccines to US customers

Novartis announced today that it has begun shipment of its seasonal influenza vaccines to customers in the US market for the 2013-2014 season. Novartis plans to ship a minimum of 30 million doses of its influenza vaccines to the US market, including Fluvirin (Influenza Virus Vaccine), approved for use in people 4 years of age and older, and Flucelvax (Influenza Virus Vaccine), approved for use in adults 18 years of age and older.

22 Aug 2013

Study shows ART has reduced immunosuppression and viremia among PHIV youth

The advent of antiretroviral therapy (ART) has transformed HIV from a death sentence into a chronic disease. In one of the largest studies of perinatally infected HIV (PHIV) patients to date, Agwu, et al, found that the proportion of patients on ART has increased and rates of viremia and advanced immunosuppression have decreased. But the rates of both markers in older patients are higher, according to an article in the Fall issue of The Journal of the Pediatric Infectious Diseases Society (JPIDS).

20 Aug 2013

Second GSK intramuscular quadrivalent influenza vaccine approved by the FDA

GlaxoSmithKline plc [LSE/NYSE: GSK] announced that the U.S. Food and Drug Administration (FDA) has approved FLULAVAL® QUADRIVALENT (Influenza Virus Vaccine) for the active immunization of persons three years of age and older to help prevent disease caused by seasonal influenza (flu) virus subtypes A and B contained in the vaccine.

19 Aug 2013

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Cedars-Sinai Medical Center has launched a Phase I clinical trial to study the safety and tolerability of an experimental immunization to treat Alzheimer's disease. The treatment is based on Copaxone (glatiramer acetate), a drug often prescribed to reduce the frequency of multiple sclerosis relapses.

13 Aug 2013

Phase I clinical trial: Sanaria PfSPZ Vaccine provides complete protection against malaria

Results of a phase I clinical trial of the Sanaria PfSPZ Vaccine to combat malaria, published today in the online issue of Science magazine, show that the vaccine provided complete protection against malaria in subjects who were exposed to Plasmodium falciparum parasites. Plasmodium falciparum is the malaria parasite that causes more than 600,000 deaths annually.

9 Aug 2013

Investigational malaria vaccine offers protection against malaria infection in healthy adults

An investigational malaria vaccine has been found to be safe, to generate an immune system response, and to offer protection against malaria infection in healthy adults, according to the results of an early-stage clinical trial published Aug. 8 in the journal Science.

9 Aug 2013

Immunization News and Research

New report shows 6.6 million children under 5 died in 2012

Undervaccination results in increased risk for whooping cough in young children

State highlights: Texas Gov. Perry touts tort reform; Calif. lawmakers want to pass 100 bills per day

Unique mobile app allows parents to access information about safety of vaccines

2D Barcoding of U.S. vaccines: an interview with Dr. Leonard Friedland, VP, Director, Scientific Affairs and Public Health, GSK Vaccines North America

First Edition: September 10, 2013

Roche, Inovio Pharmaceuticals to develop DNA-based vaccines for prostate cancer and hepatitis B

Safety and health checklist to help kids avoid emergency room

Study finds similar antibody levels among 4 PCV13 immunization schedules

New influenza vaccine delivered via microneedle avoids pain and side effects

Taiwan's HBV immunization program for newborns lowers chronic HBV carriers, incidence of HCC

New recombinant antibody can recognize MSCs in umbilical cord blood

Infant rotavirus vaccination reduced severe gastroenteritis among U.S. children

Sanofi Pasteur reports clinical benefit of Fluzone High-Dose vaccine in preventing influenza

Novartis starts shipment of 2013-2014 seasonal influenza vaccines to US customers

Study shows ART has reduced immunosuppression and viremia among PHIV youth

Second GSK intramuscular quadrivalent influenza vaccine approved by the FDA

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Phase I clinical trial: Sanaria PfSPZ Vaccine provides complete protection against malaria

Investigational malaria vaccine offers protection against malaria infection in healthy adults

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