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Yale researchers confirm NF1 gene as major player in development of skin cancer

A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.

28 Jul 2015

Rutgers physicians use new treatments to restore teenager’s life

At first, 13-year-old Christina Blumstein thought she had an ordinary headache. She and her parents were returning from a visit to Long Island in July 2014 when the pain struck. Was it a bout of carsickness? Too much screen time on her iPad? But a few hours later, back home in Old Bridge, New Jersey, her mother MaryAnn says, "Christina started screaming that somebody was stabbing her in the head with a knife." Soon afterward Christina was comatose and in an ambulance - and her life was in grave danger.

25 Jul 2015

New diagnostic criteria can help distinguish malignant cancerous chest cavity masses from histoplasmosis

Researchers led by St. Jude Children's Research Hospital scientists have developed new diagnostic criteria to enable clinicians to distinguish malignant cancerous chest cavity masses from those caused by fungal histoplasmosis infection.

23 Jul 2015

Managing Director of Messe Düsseldorf issues statement on upcoming MEDICA 2015

To get to the top is difficult; to stay at the top is even more difficult. Every athlete knows that and this also applies to the trade show business.

21 Jul 2015

New approach to imaging glucose uptake activity in single living cells

Researchers at Columbia University have reported a new approach to visualize glucose uptake activity in single living cells by light microscopy with minimum disturbance. In a recent study published in Angewandte Chemie International Edition, Associate Professor of Chemistry Wei Min's team developed a new glucose analogue that can mimic the natural glucose, and imaged its uptake as energy source by living cancer cells, neurons and tissues at the single cell level.

20 Jul 2015

UofL conducts Phase I research study for children with relapsed tumors

Zach feels "pretty good." Sam wants to be "done with shots!" And Tyler finds it helps to "just keep thinking that at least I'm getting out of school." They are normal boys who had normal lives until cancer came into the picture. All have faced the disease for two years or more, with surgeries, chemotherapy and radiation treatments. All were diagnosed with various malignant solid tumors, went into remission and then relapsed.

17 Jul 2015

Noninvasive prenatal testing clue to maternal malignancy

A preliminary study lends support to the hypothesis that a false-positive noninvasive prenatal test finding could be due to the presence of an occult maternal cancer.

16 Jul 2015

New treatment improves outcome for early FDG-PET-positive patients with stages I/II Hodgkin lymphoma

Final results of the randomized intergroup EORTC, LYSA (Lymphoma Study Association), FIL (Fondazione Italiana Linfomi) H10 trial presented at the 13th International Conference on Malignant Lymphoma in Lugano, Switzerland, on 19 June 2015 show that early FDG-PET ( 2-deoxy-2[F-18]fluoro-D-glucose positron emission tomography) adapted treatment improves the outcome of early FDG-PET-positive patients with stages I/II Hodgkin lymphoma.

16 Jul 2015

Apogenix signs licensing agreement with CANbridge to commercialize APG101 in China, Macao and Hong Kong

Apogenix, a next generation immuno-oncology company, announced today that it has entered into an exclusive licensing agreement with CANbridge Life Sciences, a biopharmaceutical company focused on developing Western drug candidates in China and North Asia, for the development and commercialization of lead immuno-oncology drug candidate APG101 in China, Macao, and Hong Kong.

15 Jul 2015

Researchers identify genetic abnormalities that lead to skin SCC

Squamous cell carcinoma (SCC) of the skin is one of the most frequent cancers in humans affecting more than half million new persons every year in the world. The transformation of a normal cell to a cancer cell is caused by an accumulation of genetic abnormalities in the progeny of single cells. The spectrum of genetic anomalies found in a variety of human cancers have been described.

14 Jul 2015

University of Twente scientists take significant step in breast cancer research

Scientists at the research Institute MIRA at the University of Twente have been working for some time on a new technique to detect breast cancer. The technique based on the physical principle of photoacoustics, has been christened PAMmography. It uses short bursts of light that cause ultrasonic waves to be generated in places with high density of blood vessels, such as in the vicinity of malignant tumours.

13 Jul 2015

Dual breast exam using MRI and NIRST more accurate than MRI alone

By combining two modalities of imaging, investigators from Norris Cotton Cancer Center at Dartmouth, led by Keith Paulsen, PhD with first author Michael Mastanduno and collaborators from Xijing Hospital in Xian, China, demonstrated that a dual breast exam using MRI and Near Infrared Spectral Tomography (NIRST) is feasible and more accurate than MRI alone.

10 Jul 2015

Molecular cancer expert David Livingston named recipient of Basser Global Prize

The Basser Center for BRCA at Penn's Abramson Cancer Center has announced the recipient of its third annual Basser Global Prize. The honor will go to molecular cancer expert David Livingston, MD, Emil Frei Professor of Genetics and Medicine at Harvard Medical School, and deputy director of the Dana-Farber/Harvard Cancer Center.

10 Jul 2015

Researchers identify five recurrent fusion genes involved in acute gastritis and cancer

Studying the gastric cancers of 15 Southeast Asian patients, researchers at The Jackson Laboratory, the Genome Institute of Singapore and other institutions identified five recurrent fusion genes, one of which appears to lead to cellular changes involved in acute gastritis and cancer.

10 Jul 2015

New screening program using CT scan technology can help better detect lung cancer in smokers

Long-time smokers and past smokers now have a more accurate way of detecting whether or not they have lung cancer thanks to a comprehensive lung cancer screening program that uses CT scan technology at Intermountain Medical Center in Salt Lake City.

10 Jul 2015

Janssen-sponsored Phase 2b trial shows guselkumab effective in treating moderate to severe plaque psoriasis

Results published today in The New England Journal of Medicine from a Janssen Research & Development, LLC (Janssen)-sponsored Phase 2b trial showed up to 86 percent of patients with moderate to severe plaque psoriasis receiving guselkumab (CNTO 1959) achieved a Physician's Global Assessment (PGA) score of cleared psoriasis or minimal psoriasis at week 16, the study's primary endpoint.

9 Jul 2015

Risk of hepatobiliary cancer, cardiovascular diseases later in life is higher in women with ICP

In a new study of more than 125,000 pregnant women in Sweden, researchers found that the risk of hepatobiliary cancer and immune-mediated and cardiovascular diseases later in life is higher in women with intrahepatic cholestasis of pregnancy (ICP) than in women without this condition.

9 Jul 2015

UC San Diego, GSK collaborate to treat leukemia by eliminating cancer stem cells

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center are working with GSK on a bench-to-bedside project to treat leukemia and other diseases by eliminating cancer stem cells. The collaboration is part of GSK's Discovery Partnerships with Academia (DPAc) program, where academic partners become core members of drug-hunting teams.

9 Jul 2015

Defects in mitochondria play key role in transition of normal cells to cancerous cells

Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.

9 Jul 2015

Scientists elucidate which mechanisms block natural killer cells and how this could be lifted

Natural killer cells of the immune system can fend off malignant lymphoma cells and thus are considered a promising therapeutic approach. However, in the direct vicinity of the tumor they lose their effect.

8 Jul 2015

Malignant News and Research

Yale researchers confirm NF1 gene as major player in development of skin cancer

Rutgers physicians use new treatments to restore teenager’s life

New diagnostic criteria can help distinguish malignant cancerous chest cavity masses from histoplasmosis

Managing Director of Messe Düsseldorf issues statement on upcoming MEDICA 2015

New approach to imaging glucose uptake activity in single living cells

UofL conducts Phase I research study for children with relapsed tumors

Noninvasive prenatal testing clue to maternal malignancy

New treatment improves outcome for early FDG-PET-positive patients with stages I/II Hodgkin lymphoma

Apogenix signs licensing agreement with CANbridge to commercialize APG101 in China, Macao and Hong Kong

Researchers identify genetic abnormalities that lead to skin SCC

University of Twente scientists take significant step in breast cancer research

Dual breast exam using MRI and NIRST more accurate than MRI alone

Molecular cancer expert David Livingston named recipient of Basser Global Prize

Researchers identify five recurrent fusion genes involved in acute gastritis and cancer

New screening program using CT scan technology can help better detect lung cancer in smokers

Janssen-sponsored Phase 2b trial shows guselkumab effective in treating moderate to severe plaque psoriasis

Risk of hepatobiliary cancer, cardiovascular diseases later in life is higher in women with ICP

UC San Diego, GSK collaborate to treat leukemia by eliminating cancer stem cells

Defects in mitochondria play key role in transition of normal cells to cancerous cells

Scientists elucidate which mechanisms block natural killer cells and how this could be lifted

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