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Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

St. Jude Children's Research Hospital investigators have completed the most comprehensive analysis yet of a common pediatric solid tumor, identifying weaknesses to target and a promising precision medicine that is now in clinical trials.

23 Aug 2018

Surgically-removed tumor specimens can help quickly evaluate cancer drug efficacy

Genetic differences can affect the susceptibility of cancer cells to different drugs. In a new Molecular Oncology study, investigators show that surgically-removed breast and prostate tumor specimens can be used to rapidly screen different drugs to see which ones most effectively target an individual's cancer cells.

22 Aug 2018

Discovery could lead to new targeted treatment for people with lung cancer

Scientists have identified a key molecular player in a subtype of lung cancer which could lead to a new way to tackle the disease, according to research published in Nature Communications.

22 Aug 2018

Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

A few little cells that are different from the rest can have a big effect. For example, individual cancer cells may be resistant to a specific chemotherapy--causing a relapse in a patient who would otherwise be cured. In the journal Angewandte Chemie, scientists have now introduced a microfluidics-based chip for the manipulation and subsequent nucleic-acid analysis of individual cells.

17 Aug 2018

Federal advisory group publishes recommendations on prevention of acute, chronic pain

A University of Texas at Arlington professor led a federal advisory group that has published its recommendations on the prevention of acute and chronic pain to the Federal Research Pain Strategy, an interagency committee that oversees the government's long-term strategic plan to support pain research.

17 Aug 2018

Tufts researchers win grant to study integration of genomic sequencing into neonatal care

Tufts Medical Center researchers have received a five-year grant award for more than $8 million from the National Center For Advancing Translational Sciences of the National Institutes of Health to study the integration of targeted genomic sequencing into neonatal diagnosis and care.

16 Aug 2018

Distinct origin of ADHD identified In children with history of traumatic brain injury

According to a study in Biological Psychiatry, physical brain injury in children contributes to the development of attention-deficit/hyperactivity disorder (ADHD), distinct from genetic risk for the disorder.

14 Aug 2018

New study explains why women get more migraines than men

Research published today reveals a potential mechanism for migraine causation which could explain why women get more migraines than men.

14 Aug 2018

Study compares genetic and neural contributions to ADHD in children with or without TBI

14 Aug 2018

Researchers show how specialized nucleic acid-based nanostructures could help target cancer cells

More than 100 years ago, German Nobel laureate Paul Ehrlich popularized the "magic bullet" concept -- a method that clinicians might one day use to target invading microbes without harming other parts of the body. Although chemotherapies have been highly useful as targeted treatments for cancer, unwanted side effects still plague patients.

14 Aug 2018

New method provides a 'big picture' of genetic influences on traits and diseases

Scientists at Johns Hopkins Bloomberg School of Public Health have developed a powerful method for characterizing the broad patterns of genetic contributions to traits and diseases. The new method provides a "big picture" of genetic influences that should be particularly helpful in designing future genetic studies and understanding potential for genetic risk prediction.

14 Aug 2018

NIH awards $6.5 million to establish multi-institution biomedical technology resource center

The National Institutes of Health have awarded $6.5 million to a consortium that includes the Icahn Institute for Genomics and Multiscale Biology at the Icahn School of Medicine at Mount Sinai, the University of Washington, the University of Connecticut, and the University of Auckland, New Zealand, to establish the Center for Reproducible Biomedical Modeling.

13 Aug 2018

Helmholtz Zentrum München appoints Professor Matthias Tschöp as new CEO

Professor Matthias Tschöp, MD, has been appointed the new CEO of Helmholtz Zentrum München. He took over from Professor Günther Wess, who led the center for the past 13 years.

10 Aug 2018

Game theory can be used to identify potential flaws in current cancer treatment approaches

Game theory can be utilized to identify potential flaws in current cancer treatment approaches and suggest new strategies to improve outcomes in patients with metastatic cancer, according to a new article published online today by JAMA Oncology.

10 Aug 2018

Scientists find genetic marker that indicates a person's risk for tachycardia-induced cardiomyopathy

Scientists in Japan have found a potential marker to identify which people with abnormally fast heartbeats are at high risk of developing heart failure.

9 Aug 2018

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in August.

9 Aug 2018

Precision Medicine News and Research

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

Surgically-removed tumor specimens can help quickly evaluate cancer drug efficacy

Discovery could lead to new targeted treatment for people with lung cancer

Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

Federal advisory group publishes recommendations on prevention of acute, chronic pain

Tufts researchers win grant to study integration of genomic sequencing into neonatal care

Distinct origin of ADHD identified In children with history of traumatic brain injury

New study explains why women get more migraines than men

Study compares genetic and neural contributions to ADHD in children with or without TBI

Researchers show how specialized nucleic acid-based nanostructures could help target cancer cells

New method provides a 'big picture' of genetic influences on traits and diseases

NIH awards $6.5 million to establish multi-institution biomedical technology resource center

Helmholtz Zentrum München appoints Professor Matthias Tschöp as new CEO

Game theory can be used to identify potential flaws in current cancer treatment approaches

Scientists find genetic marker that indicates a person's risk for tachycardia-induced cardiomyopathy

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

Cancer cells release biological 'drones' to assist in the fight against immune system

Researchers use PET tracer to identify ER expression differences in metastatic breast cancer patients

Insulin resistance largely undetected in non-diabetic patients with Parkinson's disease

New study uses metabolomics to compare lipid profiles of infant formulas and human milk

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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