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Patient characteristics may guide TKI use in CML

The likelihood of complications associated with tyrosine kinase inhibitor therapy in patients with chronic myeloid leukaemia may be reduced by considering patient factors and differences in the toxicity profiles of the different drug options, a review suggests.

29 May 2015

Measuring kidney function and damage may help predict people at risk for heart disease

Simple measures of kidney function and damage may be just as good at predicting who is at risk for heart failure and death from heart attack and stroke as traditional tests of cholesterol levels and blood pressure, new Johns Hopkins Bloomberg School of Public Health-led research suggests.

29 May 2015

New research shows wide variation in organ donation rates across the country

More than 123,000 Americans are currently waiting for lifesaving organ transplants, but 21 patients die each day because there aren't enough organs to go around. New research shows wide variation in the number of eligible organ donors whose loved ones consent to organ donation across the country.

29 May 2015

Neurosurgeon performs first endoscopic removal of spinal tumor at Rhode Island Hospital

The spinal tumor grew back. Even though the 16-year old patient endured surgery a year earlier to remove and diagnose the lesion, it was back and its cause unknown. Determined to identify the tumor tissue and set the patient on an appropriate treatment regimen, Albert Telfeian, M.D., a neurosurgeon at Rhode Island Hospital and Hasbro Children's Hospital, performed the first reported case of extracting the tumor endoscopically while the patient was awake and under a local anesthetic.

29 May 2015

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Sanford-Burnham Medical Research Institute at Lake Nona today announced it has signed a two-year partnership agreement with Takeda Pharmaceutical Company Ltd. of Japan to study the potential role of several gene regulatory proteins as targets for the treatment of heart failure.

29 May 2015

Tackling comorbidities could improve MS survival

Survival of patients with multiple sclerosis is still reduced, despite recent improvements, say researchers.

28 May 2015

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced the initiation of CALLISTO, a new comprehensive clinical research program for their novel oral anticoagulant, rivaroxaban, in patients with active cancer. The studies are evaluating the medicine for the prevention and treatment of life-threatening blood clots in patients with a wide range of cancer types.

28 May 2015

Study explores accuracy of body weight perception and obesity in Chinese Americans

Worldwide, obesity is becoming more prevalent. According to The World Health Organization, worldwide obesity has nearly doubled since 1980, and in 2008 25% of adults aged 20 and over were overweight, and another 11% were obese. Obesity has been identified as a major source of unsustainable health costs and numerous adverse outcomes, including morbidity and mortality due to hypertension, type 2 diabetes, cardiovascular diseases and certain types of cancer.

28 May 2015

TSRI scientists awarded $2.2 million NIH grant to advance innovative approach to obesity treatment

Scientists from the Florida campus of The Scripps Research Institute have been awarded nearly $2.2 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health to advance an innovative approach to the treatment of obesity, a serious health problem that affects more than one-third of all Americans.

28 May 2015

Modest lifestyle changes help breast cancer survivors lose weight

Carrying extra body fat increases the risk for diabetes, heart disease and stroke, and also increases risk of cancer recurrence after a breast cancer diagnosis. A multi-institutional study presented at the American Society for Clinical Oncology Annual Meeting 2015 shows that female breast cancer survivors are able to lose weight through modest lifestyle changes.

28 May 2015

UM researcher receives grant to examine effects of CBT on racial/ethnic minority smokers

Numerous studies have shown that African Americans and Hispanics are less likely than Caucasians to quit smoking, even if they participate in cessation interventions.

28 May 2015

FEV1/FVC lower limit of normal aids surgery risk stratification in COPD

Researchers say that using the lower limit of normal of the forced expiration volume in 1 second/forced vital capacity ratio improves risk stratification in patients with chronic obstructive pulmonary disease undergoing thoracic surgery.

27 May 2015

Positive clinical data of CytRx's aldoxorubicin to be presented at ASCO 2015

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today announced an upcoming poster presentation regarding its lead drug candidate, aldoxorubicin, at the 2015 American Society of Clinical Oncology Annual Meeting, which is being held May 29 - June 2, 2015 in Chicago.

27 May 2015

Research findings cast new light on biological process that can lead to diabetes

Oklahoma Medical Research Foundation scientists have pinpointed a cell that begins the process of scarring in fatty tissue. The findings cast new light on a biological process that occurs with obesity and can lead to diabetes.

27 May 2015

People who have higher HDL function experience fewer heart attacks later in life

HDL is the 'good cholesterol' that helps remove fat from artery walls, reversing the process that leads to heart disease. Yet recent drug trials and genetic studies suggest that simply pushing HDL levels higher doesn't necessarily reduce the risk of heart disease.

27 May 2015

New testing method could help get faster results, reduce volume of urine needed for sample

If you've been to the doctor, you probably know what to do when you're handed a plastic cup and shown to the bathroom. Most patients hand over the sample and give little thought to what happens when it's shipped to the lab for analysis. Ken Marcus and his students are the exceptions. They have developed a new testing method that they believe will reduce costs, get faster results and lower the volume of urine needed for a sample.

27 May 2015

Canadian researchers shed light on molecular dynamics of chronic pain

Chronic pain affects hundreds of millions of people worldwide and is a major cause of disability, causing more disability than cancer and heart disease. Canadian researchers, including Michael Salter at SickKids are shedding light on the molecular dynamics of chronic pain. They have uncovered a critical role for a class of cells present in the brain and spinal cord, called microglia, in pain.

27 May 2015

New investments may enable two Canadian organizations to improve life for people with hearing loss

New investments from public and private sources in Canada and the USA, including Grand Challenges Canada and Google.org, will enable two Canadian organizations to contribute to a better life for people with hearing loss in developing countries.

27 May 2015

Mast Therapeutics initiates Phase 3 extension study of vepoloxamer in sickle cell disease

Mast Therapeutics, Inc., a clinical-stage biopharmaceutical company leveraging its molecular adhesion and sealant technology (MAST) platform to develop novel therapies for sickle cell disease, heart failure, and arterial disease, today reported that it has initiated an open-label, multicenter Phase 3 extension study of vepoloxamer (MST-188) in sickle cell disease, referred to as "EPIC-E."

26 May 2015

New adjustable female shoe based on smart materials may prevent common foot problems

A new adjustable female shoe based on a new memory shape composite of leather and Nitinol material, is now available. The new material allows fitting the shoe to the foot shape, after obtaining anthropometric measurements through the Shopintantshoe portable scanner and modifying it with the "Shoptool", a machine that completes the process directly in the shop.

26 May 2015

Heart News and Research

Patient characteristics may guide TKI use in CML

Measuring kidney function and damage may help predict people at risk for heart disease

New research shows wide variation in organ donation rates across the country

Neurosurgeon performs first endoscopic removal of spinal tumor at Rhode Island Hospital

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Tackling comorbidities could improve MS survival

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

Study explores accuracy of body weight perception and obesity in Chinese Americans

TSRI scientists awarded $2.2 million NIH grant to advance innovative approach to obesity treatment

Modest lifestyle changes help breast cancer survivors lose weight

UM researcher receives grant to examine effects of CBT on racial/ethnic minority smokers

FEV1/FVC lower limit of normal aids surgery risk stratification in COPD

Positive clinical data of CytRx's aldoxorubicin to be presented at ASCO 2015

Research findings cast new light on biological process that can lead to diabetes

People who have higher HDL function experience fewer heart attacks later in life

New testing method could help get faster results, reduce volume of urine needed for sample

Canadian researchers shed light on molecular dynamics of chronic pain

New investments may enable two Canadian organizations to improve life for people with hearing loss

Mast Therapeutics initiates Phase 3 extension study of vepoloxamer in sickle cell disease

New adjustable female shoe based on smart materials may prevent common foot problems

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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