Genetic News and Research

RSS

CRISPR-Cas9 gene-editing technology targets every gene in the genome in animal cancer model

For the first time, CRISPR-Cas9 gene-editing technology has been employed in a whole organism model to systematically target every gene in the genome.

6 Mar 2015

Better interventions possible for children experiencing acute psychosis with antibodies

Antibodies defend the body against bacterial, viral, and other invaders. But sometimes the body makes antibodies that attack healthy cells. In these cases, autoimmune disorders develop.

6 Mar 2015

Biomarker for compilation of Risk Score for non-alcoholic steatohepatitis

40 percent of people in the EU suffer from non-alcoholic steatohepatitis (fatty liver disease), a disease which is becoming increasingly more frequent as a result of diabetes and excess weight in an affluent society. Currently, it is not possible to forecast the further course of the disease - right up to cirrhosis and cancer of the liver. Furthermore, an increased risk of heart attack and kidney damage exists. In future, this should become possible using a Risk Score with different biomarkers.

6 Mar 2015

RBFox2 protein plays critical role in heart failure

Researchers at the University of California, San Diego School of Medicine have identified a key piece in the complex molecular puzzle underlying heart failure - a serious and sometimes life-threatening disorder affecting more than 5 million Americans.

5 Mar 2015

Blue Cross Blue Shield of Michigan, UMHS announce new initiative to enhance genetic testing practices

Blue Cross Blue Shield of Michigan and the University of Michigan Health System are collaborating with physicians and laboratories across the state as part of a new initiative to improve genetic testing practices.

5 Mar 2015

Medical Diagnostic Laboratories now offers new HPV tests

Medical Diagnostic Laboratories, L.L.C., a CLIA-certified, CAP-accredited laboratory which specializes in high complexity, state-of-the-art, automated DNA-based molecular analyses, announces that it is now offering new Human Papillomavirus (HPV) testing which utilizes cutting edge technology, including next- generation DNA sequencing platforms.

5 Mar 2015

Pediatric Cancer Genome Project identifies genetic basis of three pediatric melanoma subtypes

The St. Jude Children's Research Hospital—Washington University Pediatric Cancer Genome Project found that melanoma in some adolescent and adult patients involves many of the same genetic alterations and would likely respond to the same therapy.

5 Mar 2015

UIC researchers identify genetic variation that increases MS risk in women

Researchers at the University of Illinois at Chicago have identified a genetic variation that in women significantly increases their risk of developing multiple sclerosis.

5 Mar 2015

New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

A new sequencing technique may provide a clearer picture of how genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's inherited risk for diabetes, heart disease and cancer, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nucleic Acids Research.

5 Mar 2015

Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

A study from researchers at Massachusetts General Hospital and Brigham and Women's Hospital reveals for the first time exactly how mutations associated with the most common form of inherited Alzheimer's disease produce the disorder's devastating effects.

5 Mar 2015

Researchers discover retina protein crucial for vision

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the LSU Health New Orleans Neuroscience Center of Excellence, discovered a protein in the retina that is crucial for vision. The paper reports, for the first time, the key molecular mechanisms leading to visual degeneration and blindness.

5 Mar 2015

Finding may help advance experimental approach to improving public health

Scientists have discovered a new way to manipulate how cells function, a finding that might help advance an experimental approach to improving public health: DNA vaccines, which could be more efficient, less expensive and easier to store than traditional vaccines.

5 Mar 2015

GeneSight test better predicts antidepressant outcomes for patients with depression

The combinatorial, multi-gene GeneSight test has been found to better predict antidepressant treatment outcomes for patients with depression, and their use of health care resources, than any of the individual genes that comprise the test, according to a peer-reviewed analysis by investigators from the Mayo Clinic and Assurex Health, and published online by The Pharmacogenomics Journal.

5 Mar 2015

Changing breast cancer cells' shape could make the disease more sensitive to treatments

Changing the shape of breast cancer cells could make the disease more sensitive to treatments - even driving the body's own inflammatory response against a tumour - a new study shows.

4 Mar 2015

Environmental conditions play significant role in determining growth, height

If you've ever wondered why you aren't a little taller, it turns out it's not all about genetics. In findings published in the Journal of Pediatrics (January 2015), an Israeli research team shows that the environment in which one lives from the womb to about age one largely determines an adult's height.

4 Mar 2015

New study shows who benefits most from statin therapy

Research has demonstrated that the risk for developing coronary heart disease depends on a host of risk factors that are related both to lifestyle and genetics. In a new study from Brigham and Women's Hospital, Washington University School of Medicine in St. Louis, and Massachusetts General Hospital, researchers tested whether a composite of genetic variants could identify the risk of cardiovascular death and heart attacks as well as identify individuals who derived greater clinical benefit from statin therapy.

4 Mar 2015

UCLA life scientists develop new method to find genetic markers for many diseases

UCLA life scientists have created an accurate new method to identify genetic markers for many diseases -- a significant step toward a new era of personalized medicine, tailored to each person's DNA and RNA.

4 Mar 2015

Study on spider venom may lead to new class of potent painkillers

New research shows that seven compounds of the countless found in spider venom block a key step in the body's ability to pass pain signals to the brain. The hunt for a medicine based on just one of these compounds, which would open up a new class of potent painkillers, is now a step closer according to new research published in the British Journal of Pharmacology.

4 Mar 2015

Study: Family Based Interpersonal Psychotherapy effective in treating preadolescents with depression

A recent study published in the March 2015 issue of the Journal of the American Academy of Child and Adolescent Psychiatry finds that Family Based Interpersonal Psychotherapy (FB-IPT) is more effective in treating preadolescent children with depression compared to child-centered therapy (CCT).

4 Mar 2015

MD Anderson scientists show why some brain cancer patients develop resistance to treatments

Scientists at The University of Texas MD Anderson Cancer Center may have discovered why some brain cancer patients develop resistance to standard treatments including radiation and the chemotherapy agent temozolomide.

3 Mar 2015

Genetic News and Research

CRISPR-Cas9 gene-editing technology targets every gene in the genome in animal cancer model

Better interventions possible for children experiencing acute psychosis with antibodies

Biomarker for compilation of Risk Score for non-alcoholic steatohepatitis

RBFox2 protein plays critical role in heart failure

Blue Cross Blue Shield of Michigan, UMHS announce new initiative to enhance genetic testing practices

Medical Diagnostic Laboratories now offers new HPV tests

Pediatric Cancer Genome Project identifies genetic basis of three pediatric melanoma subtypes

UIC researchers identify genetic variation that increases MS risk in women

New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

Researchers discover retina protein crucial for vision

Finding may help advance experimental approach to improving public health

GeneSight test better predicts antidepressant outcomes for patients with depression

Changing breast cancer cells' shape could make the disease more sensitive to treatments

Environmental conditions play significant role in determining growth, height

New study shows who benefits most from statin therapy

UCLA life scientists develop new method to find genetic markers for many diseases

Study on spider venom may lead to new class of potent painkillers

Study: Family Based Interpersonal Psychotherapy effective in treating preadolescents with depression

MD Anderson scientists show why some brain cancer patients develop resistance to treatments

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News