Heart News and Research

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Experimental gene therapy holds promise against metastatic prostate cancer

Even with the best available treatments, the median survival of patients with metastatic, hormone-refractory prostate cancer is only two to three years. Driven by the need for more effective therapies for these patients, researchers at VCU Massey Cancer Center and the VCU Institute of Molecular Medicine have developed a unique approach that uses microscopic gas bubbles to deliver directly to the cancer a viral gene therapy in combination with an experimental drug that targets a specific gene driving the cancer's growth.

12 May 2015

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Increased vascular stiffness has been identified as an important part of hypertension in aging adults. Previous studies of aortic stiffness have focused on changes in structural proteins that alter the properties of vascular walls causing them to become rigid.

11 May 2015

Immune system plays surprising role in the progression of Rett syndrome

New research by investigators at the University of Massachusetts Medical School suggests the immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting children. Immune cells known as macrophages are unable to perform their normal function and are instead amplifying the disease.

11 May 2015

Preventice Solutions announces commercial availability of BodyGuardian Heart and PatientCare Platform

Preventice Solutions announced today that BodyGuardian Heart Remote Patient Monitoring System and PatientCare platform will be commercially available in Q3, 2015. Testing with the BodyGuardian Remote Monitoring System is underway nationally to ensure ongoing improvements and care team efficiency.

11 May 2015

Overview of Blueprint Medicines' kinase drug discovery strategy published in JCI

Blueprint Medicines today announced that the Journal of Clinical Investigation published an overview of the Company's kinase drug discovery and development strategy. The publication underscores Blueprint Medicines' focus on identifying novel genomically defined disease drivers and the use of novel chemistry from its proprietary compound library to craft highly selective kinase inhibitors for new and difficult-to-drug kinase targets.

11 May 2015

Raising lupus awareness: an interview with Professor Ramsey-Goldman, MD

Lupus is a chronic, autoimmune disease, with many different symptoms so it is hard to diagnose. It affects each person differently and it has an unpredictable disease course with flare ups and quiet time. Some patients describe lupus as if they are riding a roller coaster with blinders on because they cannot always tell when they will feel well or sick...

11 May 2015

Workplace mindfulness-based intervention reduces stress levels and risk of burnout

A study by researchers at The Ohio State University Wexner Medical Center found that a workplace mindfulness-based intervention reduced stress levels of employees exposed to a highly stressful occupational environment.

11 May 2015

Small ion pump gives new hope for severe nerve pain sufferers

A small ion pump in organic electronics is giving new hope to people suffering from severe nerve pain. Researchers at Swedish Linköping University and the Karolinska Institute are the first in the world with technology that can stop pain impulses in living, freely moving rats using the body's own pain relief signals.

11 May 2015

New data driven approach to healthcare

Isansys Lifecare Ltd, the provider of complete real-time physiological patient data services and systems, is this week celebrating its fifth anniversary...

From Isansys Lifecare Ltd. 8 May 2015

Gene expression is key to understanding differences between individuals and predisposition to disease

The Genotype-Tissue Expression (GTEx) project consortia, which includes scientists from the Centre for Genomic Regulation (CRG) in Barcelona, have now published their results from their first pilot study in three Science papers...

8 May 2015

Study: Walking and cycling to work could help reduce BMI

Leaving your car at home could help shed pounds - according to new research from the University of East Anglia and the Centre for Diet and Activity Research. New research shows that making a change from driving to work to using public transport, cycling or walking could help reduce BMI over two years.

8 May 2015

SLU professor reveals why women have higher rates of strokes than men, suggests steps to reduce risk

Each year, around 55,000 more women than men will have a stroke. Longer lifespans, pregnancies and hormones all contribute to the disparity, as do illnesses that tend to strike women more frequently. Crunch the numbers and the math adds up to more strokes for women, making it important for women monitor their risk.

8 May 2015

Study confirms link between statin drugs and diabetes risk

In a database study of nearly 26,000 beneficiaries of Tricare, the military health system, those taking statin drugs to control their cholesterol were 87 percent more likely to develop diabetes.

8 May 2015

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease.

8 May 2015

Noninvasive nuclear medicine test can help determine effectiveness of aromatase inhibitor treatment

A new, noninvasive nuclear medicine test can be used to determine whether aromatase inhibitor treatment will be effective for specific cancer patients, according to a recent study reported in The Journal of Nuclear Medicine.

8 May 2015

CHOP's patient safety team recognized for work alarm fatigue in hospital units

A patient safety team at The Children's Hospital of Philadelphia who analyzed the problem of alarm fatigue in hospital units has been recognized for the best research paper of 2014 in a journal dedicated to biomedical technology.

8 May 2015

New compound offers longer lasting painkilling effects

Medications have long been used to treat pain caused by injury or chronic conditions. Unfortunately, most are short-term fixes or cause side effects that limit their use. Researchers at the University of Missouri have discovered a new compound that offers longer lasting painkilling effects, and shows promise as an alternative to current anesthetics.

7 May 2015

Kaiser Permanente, Intermountain Healthcare to participate in U.S. News Hospital Outcome Data Disclosure Program

U.S. News & World Report, publisher of Best Hospitals and Best Children's Hospitals, today announced that Kaiser Permanente and Intermountain Healthcare will participate in the U.S. News Hospital Outcome Data Disclosure Program, a new data-collection initiative designed to evaluate hospitals more completely and give patients better information about the hospitals in their communities.

7 May 2015

UT Southwestern testing Vivistim System device in stroke patients

UT Southwestern Medical Center will be one of three national sites to pioneer U.S. testing for an implant device that stimulates the vagus nerve in stroke patients to see whether it can help restore lost arm function.

7 May 2015

Comprehensive stroke centers reduce mortality risk in patients treated for hemorrhagic stroke

New research published today in the Journal of the American Heart Association indicates that patients who are treated for hemorrhagic stroke at a comprehensive stroke center are more likely to receive specialized treatment, reducing the risk of mortality.

7 May 2015

Heart News and Research

Experimental gene therapy holds promise against metastatic prostate cancer

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Immune system plays surprising role in the progression of Rett syndrome

Preventice Solutions announces commercial availability of BodyGuardian Heart and PatientCare Platform

Overview of Blueprint Medicines' kinase drug discovery strategy published in JCI

Raising lupus awareness: an interview with Professor Ramsey-Goldman, MD

Workplace mindfulness-based intervention reduces stress levels and risk of burnout

Small ion pump gives new hope for severe nerve pain sufferers

New data driven approach to healthcare

Gene expression is key to understanding differences between individuals and predisposition to disease

Study: Walking and cycling to work could help reduce BMI

SLU professor reveals why women have higher rates of strokes than men, suggests steps to reduce risk

Study confirms link between statin drugs and diabetes risk

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Noninvasive nuclear medicine test can help determine effectiveness of aromatase inhibitor treatment

CHOP's patient safety team recognized for work alarm fatigue in hospital units

New compound offers longer lasting painkilling effects

Kaiser Permanente, Intermountain Healthcare to participate in U.S. News Hospital Outcome Data Disclosure Program

UT Southwestern testing Vivistim System device in stroke patients

Comprehensive stroke centers reduce mortality risk in patients treated for hemorrhagic stroke

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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