Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

NUS researchers find novel pathway to regulate blood pressure

New and better ways to fight hypertension and low blood pressure may be in the offing, thanks to the National University of Singapore scientists' discovery of how our blood pressure is controlled.

30 May 2018

Researchers discover key receptor molecule for flu infection

After decades of research, a research team has discovered the key receptor molecule that enhances the infection of the influenza A virus, providing a novel target for anti-flu drug development.

30 May 2018

New RNA deletion tool could help create drugs that correct genetic diseases

As scientists gain insights into which genes drive diseases, they are pursuing the next logical question: Can gene editing technologies be developed to treat or even cure those diseases? Much of that effort has focused on developing technologies such as CRISPR-Cas9, a protein-based system.

30 May 2018

Scientists develop a new approach for efficient cancer therapy

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor.

30 May 2018

Small defect in tissues can lead normal cells to take on characteristics of diseased cells

Homeowners know that one little termite can lead to big problems: while termites are efficient at gnawing away at wood, they can do even more damage if the wood is already broken or has another defect.

29 May 2018

Single spinal injection reverses chemotherapy-induced pain for months in mice

Researchers at University of California San Diego School of Medicine have found a new way to block a root cause of pain. The key is a naturally occurring protein called apolipoprotein A-I binding protein (AIBP). AIBP binds to toll-like receptor 4 (TLR4), a protein that sits on the surface of cells like an antenna, searching for signs of infection or tissue damage.

29 May 2018

Study proposes a new way to reverse the aging process

A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases - and possibly even turn back the clock on aging itself.

29 May 2018

Researchers develop innovative tool for female reproductive genetics

The fruit fly Drosophila melanogaster is a powerful model organism for studying animal and human development and disease. It is low cost, generates rapidly, and there are many tools to genetically modify its cells.

29 May 2018

Study finds link between dietary protein and heart failure risk in middle-aged men

For middle-aged men, eating higher amounts of protein was associated with a slightly elevated risk for heart failure than those who ate less protein, according to new research in Circulation: Heart Failure, an American Heart Association journal.

29 May 2018

Researchers seek new approaches to better protect the eye from glaucoma

Under the increased pressure of glaucoma, scientists want to help the neurons in our eyes better protect themselves and get better help from their friends.

29 May 2018

Higher protein intake helps heart failure patients to live longer, shows study

Heart failure patients who consume more protein live longer, according to research presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress.

28 May 2018

Young cancer survivors have higher risk of pregnancy associated heart failure, shows study

Girls who survive cancer have a higher risk of developing a deadly heart disease when pregnant later in life, according to a study presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress.

28 May 2018

Study reveals novel statistical algorithm to identify potential disease genes

A new study, affiliated with UNIST has recently presented a novel statistical algorithm, capable of identifying potential disease genes in a more accurate and cost-effective way.

26 May 2018

UVA researchers establish new guidelines for explorers of the submicroscopic world inside us

Researchers from the University of Virginia have established new guidelines for scientists mapping out the body molecule by molecule to help us better understand how our cells use metals such as iron and magnesium to maintain good health.

26 May 2018

Researchers work together to solve mystery of motor neuron death in ALS patients

As the old adage goes, 'two heads are better than one'. With the development of new technologies and increasingly specialist expertise, ground-breaking science needs to be a team effort.

25 May 2018

Lung-on-a-chip technology could streamline drug-testing for pulmonary fibrosis

Developing new medicines to treat pulmonary fibrosis, one of the most common and serious forms of lung disease, is not easy.

25 May 2018

Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

New findings could help fine-tune treatment for cancer patients

Cancer therapies that cut off blood supply to a tumor could be more effective in combination with existing chemotherapeutic drugs - according to new research from the University of East Anglia.

25 May 2018

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

Anyone who's taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure to potentially harmful chemicals are triggered by TRPA1, a calcium channel protein sometimes referred to as the "wasabi receptor."

25 May 2018

SLU researcher aims to find solutions for diabetes patients at risk of hypoglycemia

A $150,000 grant from The Leona M. and Harry B. Helmsley Charitable Trust will support research at Saint Louis University led by scientist Gina Yosten, Ph.D. Yosten's team is pursuing solutions for people with diabetes who are at risk of life-threatening drops in blood sugar known as hypoglycemia.

25 May 2018