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New technique could help reduce chances of drug failure during later stages of clinical trials

An approach that could reduce the chances of drugs failing during the later stages of clinical trials has been demonstrated by a collaboration between the University of Cambridge and pharmaceutical company GlaxoSmithKline.

2 Jun 2016

Scientists reveal how ER+ breast cancer uses cholesterol-based molecule to evade anti-hormone treatments

New research funded by Breast Cancer Now has identified how the most common breast cancers could be using a cholesterol-based molecule to evade standard anti-hormone treatments, causing patients’ disease to return.

2 Jun 2016

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Scientists at the University of Liverpool have discovered that muscle cells affected by muscular dystrophy contain high levels of an enzyme that impairs muscle repair. This finding provides a new target for potential drug treatments for the disease, which currently has no cure.

2 Jun 2016

Study reveals gpihbp1 gene could be novel target for treatment of muscular dystrophy

The average healthy man is 54 percent muscle by mass, but people with muscular dystrophy, an incurable, genetic condition, have almost no muscle at terminal stages of the disease.

2 Jun 2016

New HET wearable system may help track user’s wellness to predict asthma attacks

Researchers have developed an integrated, wearable system that monitors a user's environment, heart rate and other physical attributes with the goal of predicting and preventing asthma attacks.

2 Jun 2016

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

The U.S. Food and Drug Administration today approved the cobas EGFR Mutation Test v2, a blood-based companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved, blood-based genetic test that can detect epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer patients.

2 Jun 2016

Alcoholic individuals may form stronger memory associations with alcohol-related environmental stimuli

Drug-cue associations can have a powerful influence over individuals with drug and alcohol use disorders, often leading to relapse in those attempting to stay abstinent. Few studies have investigated how drugs affect learning or memory for drug-associated stimuli in humans.

2 Jun 2016

New drugs show promise as first antidote for radiation exposure

University of Virginia School of Medicine researchers have identified promising drugs that could lead to the first antidote for radiation exposure that might result from a dirty bomb terror attack or a nuclear accident such as Chernobyl.

2 Jun 2016

New research reveals functioning of brain's cleaning up mechanisms in neurodegenerative diseases

A piece of research led by the Achucarro Basque Center for Neuroscience, the University of the Basque Country, and the Ikerbasque Foundation has revealed how the brain's cleaning up mechanisms function in neurodegenerative diseases.

1 Jun 2016

Duke scientists discover new small-molecule drugs to treat chronic pain

A research team at Duke University has discovered a potential new class of small-molecule drugs that simultaneously block two sought-after targets in the treatment of pain.

1 Jun 2016

Suppression of ventral pallidum neurons could be key to control binge behavior

Rats that responded to cues for sugar with the speed and excitement of binge-eaters were less motivated for the treat when certain neurons were suppressed, researchers discovered.

1 Jun 2016

Denosumab drug that inhibits RANKL gene can prevent genetic breast cancer

An international team led by researchers at the Austrian Institute of Molecular Biotechnology in Vienna and the University of Maryland School of Medicine in Baltimore discovered that genetically determined breast cancer can be largely prevented by blocking a bone gene. An already approved drug could be quickly available and would then be the first breast cancer prevention drug.

1 Jun 2016

Understanding how opiates affect brain pathways to drive addiction cycle

New research by Steven Laviolette's research team at Western University is contributing to a better understanding of the ways opiate-class drugs modify brain circuits to drive the addiction cycle.

1 Jun 2016

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

On Friday, May 27, the U.S. Food and Drug Administration granted accelerated approval for Ocaliva (obeticholic acid) for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as a single therapy in adults unable to tolerate UDCA.

1 Jun 2016

AbbVie, Sanofi and Novo Nordisk listed among top 10 companies in 2016 UK Pharma RepTrak rankings

AbbVie, Sanofi and Novo Nordisk top the RepTrak® ranking of the most reputable pharmaceutical companies in the UK, Reputation Institute announced today, based on more than 1,600 ratings collected in the first quarter of 2016 from members of the UK general public.

1 Jun 2016

Study identifies persistent opioid use in some patients after knee or hip replacement

Many patients undergoing hip or knee replacement are still taking prescription opioid pain medications up to six months after surgery, reports a study in PAIN, the official publication of the International Association for the Study of Pain.

1 Jun 2016

Researchers design ProAgio protein that may potentially treat cancer, other illnesses

A protein designed by researchers at Georgia State University can effectively target a cell surface receptor linked to a number of diseases, showing potential as a therapeutic treatment for an array of illnesses, including cancer, according to the research team.

1 Jun 2016

Drugs News and Research

New technique could help reduce chances of drug failure during later stages of clinical trials

Scientists reveal how ER+ breast cancer uses cholesterol-based molecule to evade anti-hormone treatments

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Study reveals gpihbp1 gene could be novel target for treatment of muscular dystrophy

New HET wearable system may help track user’s wellness to predict asthma attacks

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

Alcoholic individuals may form stronger memory associations with alcohol-related environmental stimuli

New drugs show promise as first antidote for radiation exposure

New research reveals functioning of brain's cleaning up mechanisms in neurodegenerative diseases

Duke scientists discover new small-molecule drugs to treat chronic pain

Suppression of ventral pallidum neurons could be key to control binge behavior

Denosumab drug that inhibits RANKL gene can prevent genetic breast cancer

Understanding how opiates affect brain pathways to drive addiction cycle

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

AbbVie, Sanofi and Novo Nordisk listed among top 10 companies in 2016 UK Pharma RepTrak rankings

Study identifies persistent opioid use in some patients after knee or hip replacement

Researchers design ProAgio protein that may potentially treat cancer, other illnesses

Additional drug treatment options to prevent migraine may offer hope to sufferers

Cryptococcus research: an interview with Associate Professor Kirsten Nielsen

Cost-effective community intervention may help reduce epilepsy treatment gap in rural areas

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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