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Study finds racial disparities among children with Crohn's disease

A study published recently in the IBD Journal found significant differences in hospital readmissions, medication usage, and both medical and surgical complications of children with Crohn's disease related to race. In the study, black children had a 1.5 times higher frequency of hospital readmissions because of Crohn's disease compared to white children.

28 Feb 2015

New pharmacological compounds block nerve cell damage in mouse models of MS

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

28 Feb 2015

WHO: 1.1 billion young people at risk of hearing loss due to unsafe use of personal audio devices

Some 1.1 billion teenagers and young adults are at risk of hearing loss due to the unsafe use of personal audio devices, including smartphones, and exposure to damaging levels of sound at noisy entertainment venues such as nightclubs, bars and sporting events, according to WHO. Hearing loss has potentially devastating consequences for physical and mental health, education and employment.

27 Feb 2015

At-risk individuals show possible treatment targets for bipolar disorder

Depressive, anxiety and behavioural disorders may be important preceding clinical features in the onset of bipolar disorder, with the potential for targeted preventive care of at-risk individuals, study findings suggest.

27 Feb 2015

KU Leuven researchers devise simple, effective solution to untangle DNA

Researchers have long sought an efficient way to untangle DNA in order to study its structure - neatly unraveled and straightened out - under a microscope. Now, chemists and engineers at KU Leuven, in Belgium, have devised a strikingly simple and effective solution: they inject genetic material into a droplet of water and use a pipet tip to drag it over a glass plate covered with a sticky polymer.

27 Feb 2015

New test can predict survival chances of women with breast cancer

Scientists have developed a new test which can predict the survival chances of women with breast cancer by analysing images of 'hotspots' where there has been a fierce immune reaction to a tumour.

27 Feb 2015

Researchers reveal role of abdominal muscles in muscular dystrophy process

The muscular dystrophies are known to target various muscle groups differentially. In addition to making limb muscles weak, muscular dystrophy (MD) can also lead to decreased function of specific muscles involved in respiration causing breathing difficulties as well as leading to cardiac problems.

27 Feb 2015

New tool provides molecular details about how mutations affect cellular processes

Today in the journal Nature Methods, the laboratory headed by ICREA researcher Patrick Aloy, at the Institute for Research in Biomedicine, presents a computational tool that allows a greater understanding of the genetic causes of complex diseases such as cancer, Alzheimer's and diabetes.

27 Feb 2015

Vitamin D, omega-3 fatty acids may optimize brain serotonin concentrations and function

Although essential marine omega-3 fatty acids and vitamin D have been shown to improve cognitive function and behavior in the context of certain brain disorders, the underlying mechanism has been unclear. In a new paper published in FASEB Journal by Rhonda Patrick, PhD and Bruce Ames, PhD of Children's Hospital Oakland Research Institute, serotonin is explained as the possible missing link tying together why vitamin D and marine omega-3 fatty acids might ameliorate the symptoms associated with a broad array of brain disorders.

27 Feb 2015

Loyola physician reveals top five health concerns for men, offers tips to prevent them

Men lead women in the likelihood to die from nearly all the most common causes of death. Still, men are less likely to go to the doctor than women and often try to ignore symptoms of health problems.

27 Feb 2015

TSRI scientists show how to target weak spots of Marburg virus with future treatments

Marburg virus is Ebola's deadly cousin. The virus is up to 90 percent lethal—and doctors are desperate for tools to fight it.

27 Feb 2015

Researchers discover that cell's skeleton can trigger cell multiplication

A research team from Instituto Gulbenkian de Ciencia (IGC; Portugal), led by Florence Janody, in collaboration with Nicolas Tapon from London Research Institute (LRI; UK), discovered that the cell's skeleton can trigger the multiplication of cells through the action of proteins that control cellular rigidity.

27 Feb 2015

Targeting stroma could potentially extend survival of pancreatic cancer patients

Like a stealth jet cloaks itself from radar, cancer cells cloak themselves within tumors by hiding behind a dense layer of cellular material known as stroma.

27 Feb 2015

Study explores association between back pain and depression

Genetic factors help to explain the commonly found association between low back pain and depression, suggests a large study of twins in the March issue of PAIN, the official publication of the International Association for the Study of Pain. The journal is published by Wolters Kluwer.

26 Feb 2015

ABIVAX doses first patient in ABX203 Phase IIb/III trial for treatment of chronic hepatitis B

ABIVAX, a clinical stage biotech company developing and commercialising anti-viral compounds and human vaccines, today announced that it has dosed in New Zealand the first patient in a Phase IIb/III clinical trial of ABX203 which is taking place in several countries of the Asia-Pacific region.

26 Feb 2015

RowanSOM researcher awarded NINDS grant to develop stem cell-based therapy for Canavan disease

Paola Leone, PhD, the director of the Cell and Gene Therapy Center and a professor of Cell Biology at the Rowan University School of Osteopathic Medicine, has been awarded a three-year, $477,000 grant from the National Institute of Neurological Disorders and Stroke to develop a stem cell-based therapy for Canavan disease, a rare but devastating neurological disorder in children that typically takes a child's life by age 10.

26 Feb 2015

New four-way collaboration aims to improve clinical decision-making in the treatment of colon cancer

EKF Diagnostics subsidiary, Selah Genomics, has announced a major, four-way collaboration with Greenville Health System, DecisionQ Corporation, and BD.

From EKF Diagnostics 26 Feb 2015

Researchers reveal how malaria parasite deploys genetic trickery to escape immune system attack

Up to one million people -- mainly pregnant woman and young children -- are killed each year by the Plasmodium falciparum parasite, which causes the most devastating form of human malaria.

26 Feb 2015

New study identifies genetic link to peanut allergy

Researchers have pinpointed a region in the human genome associated with peanut allergy in U.S. children, offering strong evidence that genes can play a role in the development of food allergies.

25 Feb 2015

Monell Center to promote Anosmia Awareness Day with new educational outreach initiatives

The Monell Center announces three new educational outreach initiatives to promote Anosmia Awareness Day, which takes place on February 27. Each was designed to increase awareness and increase the limited information currently available about anosmia, the loss of our sense of smell, which affects over six million Americans and many millions more worldwide.

25 Feb 2015

Genetic News and Research

Study finds racial disparities among children with Crohn's disease

New pharmacological compounds block nerve cell damage in mouse models of MS

WHO: 1.1 billion young people at risk of hearing loss due to unsafe use of personal audio devices

At-risk individuals show possible treatment targets for bipolar disorder

KU Leuven researchers devise simple, effective solution to untangle DNA

New test can predict survival chances of women with breast cancer

Researchers reveal role of abdominal muscles in muscular dystrophy process

New tool provides molecular details about how mutations affect cellular processes

Vitamin D, omega-3 fatty acids may optimize brain serotonin concentrations and function

Loyola physician reveals top five health concerns for men, offers tips to prevent them

TSRI scientists show how to target weak spots of Marburg virus with future treatments

Researchers discover that cell's skeleton can trigger cell multiplication

Targeting stroma could potentially extend survival of pancreatic cancer patients

Study explores association between back pain and depression

ABIVAX doses first patient in ABX203 Phase IIb/III trial for treatment of chronic hepatitis B

RowanSOM researcher awarded NINDS grant to develop stem cell-based therapy for Canavan disease

New four-way collaboration aims to improve clinical decision-making in the treatment of colon cancer

Researchers reveal how malaria parasite deploys genetic trickery to escape immune system attack

New study identifies genetic link to peanut allergy

Monell Center to promote Anosmia Awareness Day with new educational outreach initiatives

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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