Nausea News and Research

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Nausea is the sensation of unease and discomfort in the upper stomach and head with an urge to vomit. An attack of nausea is known as a qualm.

Researchers develop new opioid drug for chronic pain

A team of researchers led by Andrew Coop, PhD, professor and chair of the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy, has developed a new opioid drug that shows great potential to advance treatment and improve quality of life for individuals living with chronic pain.

29 Aug 2013

HCV treatment with sofosbuvir and ribavirin results in sustained virologic response

Treatment of chronic hepatitis C virus genotype 1 infection with the interferon-free regimen of sofosbuvir and ribavirin resulted in a high sustained virologic response rate in a patient population with unfavorable treatment characteristics, according to a study in the August 28 issue of JAMA.

28 Aug 2013

FDA grants Priority Review designation to sNDA for Nexavar tablets

Bayer HealthCare and Onyx Pharmaceuticals today announced that the U.S. Food and Drug Administration has granted Priority Review designation to the supplemental New Drug Application for the oral multi-kinase inhibitor Nexavar (sorafenib) tablets under evaluation for the treatment of locally advanced or metastatic radioactive iodine-refractory differentiated thyroid cancer.

27 Aug 2013

FDA approves Galderma's Mirvaso topical gel for facial erythema of rosacea

Galderma Laboratories, L.P. announced that the U.S. Food and Drug Administration has approved Mirvaso (brimonidine) topical gel, 0.33% for the topical treatment of the facial erythema (redness) of rosacea in adults 18 years of age or older. Applied once daily, Mirvaso works quickly to reduce the redness of rosacea and lasts up to 12 hours. Galderma expects Mirvaso to be available in pharmacies September 2013.

27 Aug 2013

Aromatherapy, IV dextrose may relieve nausea and vomiting after surgery

Two simple, non-drug treatments-aromatherapy and intravenous administration of a simple sugar solution-may offer effective new approaches to relieving nausea and vomiting after surgery, report a pair of studies in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

22 Aug 2013

Nuvo: FDA accepts to review New Drug Application for PENNSAID 2%

Nuvo Research Inc., a specialty pharmaceutical company dedicated to building a portfolio of products for the topical treatment of pain and the development of its immune modulating drug candidate WF10 today announced that its U.S. licensee for PENNSAID (diclofenac sodium topical solution) 1.5% w/w and PENNSAID 2% (diclofenac sodium topical solution) 2% w/w, Mallinckrodt has advised that the U.S. Food and Drug Administration has accepted for filing and review the New Drug Application for PENNSAID 2% submitted by Mallinckrodt on August 7, 2013.

22 Aug 2013

Takeda announces publication of data from two vedolizumab Phase 3 studies for ulcerative colitis and Crohn’s disease

Takeda Pharmaceutical Company Limited today announced that results from two Phase 3 studies evaluating vedolizumab, an investigational humanized monoclonal antibody, for the treatment of adults with moderately to severely active ulcerative colitis and Crohn’s disease, were published in the August 22, 2013 issue of the New England Journal of Medicine.

22 Aug 2013

Pazopanib drug shows improved quality of life and safety in metastatic kidney cancer patients

Two oral targeted drugs approved for metastatic kidney cancer worked equally well, but one proved superior in tolerability, according to results of a large international clinical trial led by researchers at Dana-Farber Cancer Institute.

22 Aug 2013

New antibody drug shows positive results for treating Crohn's disease, ulcerative colitis

Vedolizumab, a new intravenous antibody medication, has shown positive results for treating both Crohn's disease and ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine. The findings, published in two papers, will appear in the August 22 issue of the New England Journal of Medicine (NEJM).

22 Aug 2013

Combined liposuction and tummy tuck reduce surgical trauma, provide excellent patient outcomes

A combined technique of liposuction and tummy tuck-designed to reduce surgical trauma-provides excellent patient outcomes with a low complication rate, reports a study in Plastic and Reconstructive Surgery-Global Open-, the official open-access medical journal of the American Society of Plastic Surgeons (ASPS).

21 Aug 2013

Combination of anti-nausea drug and turmeric spice target cancer cells

In a laboratory, preclinical study recently published by the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers combined structural features from anti-nausea drug thalidomide with common kitchen spice turmeric to create hybrid molecules that effectively kill multiple myeloma cells.

20 Aug 2013

Boehringer Ingelheim completes patient enrolment of two pivotal Phase III interferon-free hepatitis C clinical trials

Boehringer Ingelheim today announced that enrolment of over 950 treatment naïve genotype-1b patients in the pivotal Phase III interferon-free HCVerso™ 1 and 2 trials is complete.

15 Aug 2013

Multiple sclerosis patients see "rapid expansion" of effective new treatment options

After decades of research, multiple sclerosis patients are seeing a "rapid expansion" of effective new treatment options, according to a review article in the journal Neurologic Clinics.

14 Aug 2013

Cultural mythologies strongly influence women’s expectations during pregnancy

Morning sickness, shiny hair and bizarre and intense cravings for pickles and ice cream -- what expectations do pregnant women impose on their bodies, and how are those expectations influenced by cultural perspectives on pregnancy? University of Cincinnati researcher Danielle Bessett, an assistant professor of sociology, presented her research at the 108th annual meeting of the American Sociological Association in New York, N.Y.

14 Aug 2013

Harvard University receives grant to use organs-on-chips device to test human response to radiation

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has received a $5.6 million grant award from the United States Food and Drug Administration (FDA) to use its Organs-on-Chips technology for a novel application of keen interest to national security and health officials: to test human physiological responses to radiation, and to evaluate drugs designed to counter those effects.

13 Aug 2013

Researchers evaluate accuracy of neurocognitive testing in cheerleaders with concussion

Concussions have become a major public health issue, with both short- and long-term side effects. In sports, cheerleading has the highest rate of catastrophic injury, with some studies reporting approximately 6% of total injuries as concussions. Return-to-play guidelines have relied on athletes' self-reports; however, this has led to concerns about the ability of athletes to truly recognize their own symptoms and recovery.

9 Aug 2013

Lupin acquires exclusive license to promote, distribute Romark's Alinia for Oral Suspension in US

Romark Laboratories announced that it has entered into a strategic agreement with Lupin Limited and its subsidiaries (collectively Lupin) designed to expand promotion and distribution efforts related to its Alinia (nitazoxanide) for Oral Suspension, 100 mg/5 mL. Under the agreement, Lupin acquired an exclusive license to promote and distribute Alinia for Oral Suspension in the United States.

7 Aug 2013

Meridian Health earns Chest Pain Center Accreditation

Meridian Health, a leading New Jersey health care system, has recently earned the highest designated Chest Pain Center Accreditation by the Society of Cardiovascular Patient Care, a global not-for-profit organization committed to leading the fight to eliminate heart disease as the number one cause of death worldwide.

6 Aug 2013

European authorisation of Aegerion Pharmaceuticals' Lojuxta brings hope for HoFH patients

Aegerion Pharmaceuticals, Inc., a biopharmaceutical company dedicated to the development and commercialisation of novel, life-altering therapies for patients with debilitating, often fatal, rare diseases, announced today that the European Commission has authorised Lojuxta (lomitapide) hard capsules as an adjunct to a low-fat diet and other lipid-lowering medicinal products with or without low density lipoprotein apheresis in adult patients with homozygous familial hypercholesterolaemia.

3 Aug 2013

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

An experimental treatment for alcohol dependence works better in individuals who possess specific combinations of genes that regulate the function and binding of serotonin, a brain chemical affected by the treatment, according to a study supported by the National Institutes of Health. A report of the finding appears online in the American Journal of Psychiatry.

3 Aug 2013

Nausea News and Research

Further Reading

Researchers develop new opioid drug for chronic pain

HCV treatment with sofosbuvir and ribavirin results in sustained virologic response

FDA grants Priority Review designation to sNDA for Nexavar tablets

FDA approves Galderma's Mirvaso topical gel for facial erythema of rosacea

Aromatherapy, IV dextrose may relieve nausea and vomiting after surgery

Nuvo: FDA accepts to review New Drug Application for PENNSAID 2%

Takeda announces publication of data from two vedolizumab Phase 3 studies for ulcerative colitis and Crohn’s disease

Pazopanib drug shows improved quality of life and safety in metastatic kidney cancer patients

New antibody drug shows positive results for treating Crohn's disease, ulcerative colitis

Combined liposuction and tummy tuck reduce surgical trauma, provide excellent patient outcomes

Combination of anti-nausea drug and turmeric spice target cancer cells

Boehringer Ingelheim completes patient enrolment of two pivotal Phase III interferon-free hepatitis C clinical trials

Multiple sclerosis patients see "rapid expansion" of effective new treatment options

Cultural mythologies strongly influence women’s expectations during pregnancy

Harvard University receives grant to use organs-on-chips device to test human response to radiation

Researchers evaluate accuracy of neurocognitive testing in cheerleaders with concussion

Lupin acquires exclusive license to promote, distribute Romark's Alinia for Oral Suspension in US

Meridian Health earns Chest Pain Center Accreditation

European authorisation of Aegerion Pharmaceuticals' Lojuxta brings hope for HoFH patients

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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