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Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Researchers investigated the susceptibility of naturally-occurring severe acute respiratory syndrome coronavirus 2 main protease variants to protease inhibitor drugs, including nirmatrelvir and ensitrelvir.

11 Aug 2022

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Researchers demonstrated multiple routes SARS-CoV-2 might take to develop high-level resistance to nirmatrelvir, an oral antiviral targeting the 3C-like protease (3CLpro) of SARS-CoV-2.

11 Aug 2022

Sniffing out cancer with insect olfactory neural circuits

A fascinating new preprint reports the results of examining the VOC composition from individual cell cultures derived from human oral cancers, using an experimental setup employing an insect brain with attached antenna.

11 Aug 2022

Smoking continues to be a leading cause of cancer-related death

A new study led by researchers at the American Cancer Society (ACS) reports nearly 123,000 cancer deaths, or close to 30 percent of all cancer deaths, were from cigarette smoking in the United States in 2019, leading to more than two million Person-Years of Lost Life (PYLL) and nearly $21 billion in annual lost earnings. These losses were disproportionately higher in states with weaker tobacco control policies in the South and Midwest. The results were published today in the International Journal of Cancer.

11 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

Study findings reveal bacterial signature in the saliva of soldiers experiencing post-traumatic stress disorder

A scientific breakthrough from the Tel Aviv and Haifa Universities may facilitate speedy, objective and accurate diagnosis of people suffering from PTSD using saliva samples. As part of the study, the researchers characterized the psychological, social and medical conditions of about 200 participants, while at the same time collecting saliva samples from them.

11 Aug 2022

Appropriate and acceptable health checks can help improve outcomes in people experiencing homelessness

Appropriate and acceptable health checks for people experiencing homelessness can help reduce long-term physical and mental stresses, a new study shows.

11 Aug 2022

New CDC Vital Signs report: Few people diagnosed with hepatitis C receive timely treatment

A new CDC Vital Signs report finds that too few people diagnosed with hepatitis C are being treated, despite availability of medications capable of curing this viral infection.

10 Aug 2022

Researchers describe case report of male monkeypox patient

In a new case study, researchers described the case of a male patient with monkeypox.

10 Aug 2022

Formulary restrictions may increase the risk of stroke in patients with atrial fibrillation

Atrial fibrillation (AF) is a major risk factor for stroke, and for decades the anticoagulant warfarin was the standard treatment for lowering that hazard. However, numerous drug and food interactions make warfarin burdensome for patients.

10 Aug 2022

Using microrobotic platforms for endodontic therapy and diagnostics

With its irregularities and anatomical complexities, the root canal system is one of the most clinically challenging spaces in the oral cavity.

9 Aug 2022

Pathogens in ancient DNA could explain how two civilizations collapsed

The current study has strongly indicated the presence of Y. pestis and S. enterica on the island of Crete that contributed to societal changes during 2,000 BCE.

9 Aug 2022

New simulator quantifies the effect of body posture and stomach motility on drug bioavailability

A common, economic, and easy method of administering drugs is orally, by swallowing a pill or capsule.

9 Aug 2022

CDC and Task Force for Global Health to co-host 11th International Conference on Emerging Infectious Diseases

The Centers for Disease Control and Prevention and the Task Force for Global Health will co-host in person the 11th International Conference on Emerging Infectious Diseases August 7-10, 2022, at the Hyatt Regency Atlanta hotel in Atlanta, GA.

9 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Wrist-wearable devices more cost-effective than electrocardiograms and pulse palpation for atrial fibrillation screening

Screening individuals for atrial fibrillation (AF) using wearable devices is more cost-effective than screening using conventional methods such as 12-lead electrocardiogram (ECG) and pulse palpation, or than no screening at all, researchers from Massachusetts General Hospital (MGH) have found.

8 Aug 2022

Oral News and Research

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Sniffing out cancer with insect olfactory neural circuits

Smoking continues to be a leading cause of cancer-related death

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Study findings reveal bacterial signature in the saliva of soldiers experiencing post-traumatic stress disorder

Appropriate and acceptable health checks can help improve outcomes in people experiencing homelessness

New CDC Vital Signs report: Few people diagnosed with hepatitis C receive timely treatment

Researchers describe case report of male monkeypox patient

Formulary restrictions may increase the risk of stroke in patients with atrial fibrillation

Using microrobotic platforms for endodontic therapy and diagnostics

Pathogens in ancient DNA could explain how two civilizations collapsed

New simulator quantifies the effect of body posture and stomach motility on drug bioavailability

CDC and Task Force for Global Health to co-host 11th International Conference on Emerging Infectious Diseases

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Wrist-wearable devices more cost-effective than electrocardiograms and pulse palpation for atrial fibrillation screening

Locusts can differentiate between cancer cells and healthy cells, research shows

What does the future look like for TB care?

Can high-dose coenzyme Q10 reduce the number and severity of post-COVID-19 condition-related symptoms?

Drugs with antiviral activity against monkeypox virus

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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