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Cinnamon compound could be useful supplement to dexamethasone in COVID-19 treatment

Researchers in Germany and the United States have conducted a study showing that supplementing dexamethasone treatment with Ceylon cinnamon in cases of coronavirus disease 2019 (COVID-19) may allow dexamethasone to be administered at lower doses, thereby avoiding the side effects that occur with high doses of the steroid.

17 Jun 2021

Research may lead to rapid, accurate, point-of-care testing for COVID

A team of scientists headed by SANKEN (The Institute of Scientific and Industrial Research) at Osaka University demonstrated that single virus particles passing through a nanopore could be accurately identified using machine learning.

17 Jun 2021

Scientists reveal the mechanism of liquid-liquid phase separation of SARS-CoV-2 nucleocapsid

A team of scientists from the United States has recently revealed how interactions between the SARS-CoV-2 nucleocapsid protein and the double-stranded RNA motifs impart distinct droplet properties that can support multiple viral functions. The study is currently available on the bioRxiv* preprint server.

16 Jun 2021

Reducing coronavirus-related mortality through senolytics

A study recently published in the journal Science explores the concept of senescent cells (SnC) having a hyperinflammatory response and the use of a class of small molecules called senolytics to combat this.

16 Jun 2021

Cissampelos pareira (velvetleaf) exhibits anti-SARS-CoV-2 potential

Cissampelos pareira (Cipa), also known as velvetleaf, is a widely used hormone modulator used to treat reproductive disorders and fever. Research has shown that it can inhibit three serotypes of Dengue virus (DENV) and affect various hormones.

16 Jun 2021

A study on SARS-CoV-2 proteins for the development of COVID-19 drugs

The authors of the review have grouped the virus proteins into three categories, (a) host-entry, (b) self-acting, and (c) host-interacting. Additionally, individual SARS-CoV-2 proteins are evaluated to be either directly targeted by drugs or block virus-host interactions.

16 Jun 2021

CDC study looks at SARS-CoV-2 testing among returning cruise ship travelers

In a recent study published on the preprint server medRxiv*, a group of researchers discusses the RT-PCR results and symptoms experienced by the travelers to illustrate the viral dynamics during asymptomatic or mild COVID-19 infection.

15 Jun 2021

Could urine tests predict kidney injury and mortality in COVID-19?

A team of scientists from the Columbia University, New York, has recently identified a potential biomarker to predict acute kidney injury in COVID-19 patients. By analyzing urine samples of 444 COVID-19 patients, they have revealed that the urinary level of neutrophil gelatinase-associated lipocalin (NGAL) can be used to determine the severity and duration of acute kidney and tubular injuries, as well as to predict the risk of mortality in acute COVID-19 patients.

15 Jun 2021

South African and Brazilian SARS-CoV-2 variants overtake UK variant in French regions

Researchers have found that the variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that were initially identified in South Africa (B.1.351) and Brazil (P.1) appear to be spreading more quickly in some areas of France than the previously dominant UK variant B.1.1.7.

14 Jun 2021

Study creates a new model of Alzheimer's disease progression

Alzheimer's disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease and cause eventual neuronal death, but little is known about how other cells in the brain react during disease progression.

14 Jun 2021

UIC discovery may lead to new treatments for alcohol use disorder and depression

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression.

14 Jun 2021

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Diverse messenger RNAs are produced in cells by “alternative splicing.” The Leducq Foundation is now supporting a transatlantic network dedicated to investigating this process in heart muscle cells and how changes in this process contribute to disease. Professor Michael Gotthardt of the MDC and Professor Leslie Leinwand of the University of Colorado Boulder are coordinating the project.

14 Jun 2021

Forkhead box O's potential therapeutic use in the treatment of COVID-19

In a recent study, Indian researchers from the Department of Biochemistry, University of Delhi, reviewed a possible vital coalition of FoxOs - the Forkhead Box O subfamily of protein transcription factors, with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the etiological agent of COVID-19 (coronavirus disease).

13 Jun 2021

What makes the elderly more susceptible to SARS-CoV-2 infection?

Why is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 (coronavirus disease 2019), biased towards infecting the aged population? A recently published study by Italian scientists linked aging, DNA damage, telomere shortening, and increased levels of angiotensin-converting enzyme 2 (ACE2) to this relationship.

13 Jun 2021

SARS-CoV-2 infection detected in a poodle living with a COVID-19 positive family

Researchers in Italy identified a case of reverse zoonosis wherein animals contract the virus from humans. The team detected SARS-CoV-2 in a healthy poodle living with four family members who had COVID-19.

11 Jun 2021

New gene expression network can help understand mechanism behind continuous stem cell activity in plants

An inter-university research group has succeeded in constructing the gene expression network behind the vascular development process in plants.

11 Jun 2021

LIM domain only 1 gene contributes to the tumorigenesis of multiple cancers

Humans have been plagued by a myriad of deadly cancers since ages. Parallelly, they have also been attempting different permutations and combinations of treatments to cure the disease. Part of these attempts involving biomolecular targets have come to the fore in recent years.

10 Jun 2021

Transcription News and Research

Cinnamon compound could be useful supplement to dexamethasone in COVID-19 treatment

Research may lead to rapid, accurate, point-of-care testing for COVID

Scientists reveal the mechanism of liquid-liquid phase separation of SARS-CoV-2 nucleocapsid

Reducing coronavirus-related mortality through senolytics

Cissampelos pareira (velvetleaf) exhibits anti-SARS-CoV-2 potential

A study on SARS-CoV-2 proteins for the development of COVID-19 drugs

CDC study looks at SARS-CoV-2 testing among returning cruise ship travelers

Could urine tests predict kidney injury and mortality in COVID-19?

South African and Brazilian SARS-CoV-2 variants overtake UK variant in French regions

Study creates a new model of Alzheimer's disease progression

UIC discovery may lead to new treatments for alcohol use disorder and depression

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Forkhead box O's potential therapeutic use in the treatment of COVID-19

What makes the elderly more susceptible to SARS-CoV-2 infection?

SARS-CoV-2 infection detected in a poodle living with a COVID-19 positive family

New gene expression network can help understand mechanism behind continuous stem cell activity in plants

LIM domain only 1 gene contributes to the tumorigenesis of multiple cancers

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

New cell-penetrating peptide may protect against life-threatening microbial inflammation

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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