Antigen News and Research

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Novel strategy to produce SARS-CoV-2 nucleocapsid protein for serological testing

New research discusses an alternative method of purifying the SARS-CoV-2 N protein using only metal exchange chromatography and denaturing conditions.

18 Nov 2021

Toll-like receptor 2 - novel target for improved COVID-19 vaccines

In a new study, researchers from French and American institutes analyzed at a molecular level the interaction between SARS-CoV-2 E protein and human TLR2.

17 Nov 2021

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

Canadian public health researchers recently published a study in the journal Antiviral Research wherein they described generating a panel of murine hybridomas recognizing SARS-CoV-2 spike protein or nucleoprotein, capable of neutralizing the SARS-CoV-2 variants of concern, proving their therapeutic potential.

17 Nov 2021

Study reveals complex interplay between diet, gut microbiota, and immune function

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

17 Nov 2021

Long-term Pfizer vaccine-elicited SARS-CoV-2 antibody profile in breast milk

A new study indicates that the Pfizer vaccine induces antibodies in the breast milk against SARS-CoV-2.

17 Nov 2021

Effect of contact networks on SARS-CoV-2 transmission and control

A study demonstrated that the social contacts created in different activity settings affect interventions needed to control outbreaks.

17 Nov 2021

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

A new study published in the journal Diagnostics was based on the hypothesis that detecting urinary SARS-CoV-2 nucleic acid––which may result in renal and cardiovascular endothelial destruction to facilitate viral access to the kidney parenchyma—may be used as a specific biomarker to indicate the severity of COVID-19.

16 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

Study: Covid-19 vaccine-elicited immune cells persist six months after vaccination

A recent study by Johns Hopkins Medicine researchers provides evidence that CD4+ T lymphocytes — immune system cells also known as helper T cells — produced by people who received either of the two available messenger RNA (mRNA) vaccines for COVID-19 persist six months after vaccination at only slightly reduced levels from two weeks after vaccination and are at significantly higher levels than for those who are unvaccinated.

16 Nov 2021

SARS-CoV-2 replicates in human placenta with release of infectious viral particles

The current study analyzed the interaction of SARS-CoV-2 at the human maternal-fetal interface by using an advanced ex vivo model.

16 Nov 2021

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

A new study has described the molecular basis of the neutralization potency and breadth of nanobodies.

16 Nov 2021

Myocarditis among Moderna COVID-19 vaccine recipients

A new preprint reports on the incidence of myocarditis in a large population of over 150 million who received two doses of the first vaccine to receive emergency use authorization against the virus.

16 Nov 2021

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers conducted a comprehensive, longitudinal, long-term immune study, including functional assays to assess immune fitness against antigenically different VoC. The study is currently available on the preprint server medRxiv* while awaiting peer review.

15 Nov 2021

Researchers develop a highly efficient method to generate immune cells for cancer therapies

A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens - small fragments of randomly mutated proteins that are typically unique to a patient's cancer - and destroy the tumors that express them.

15 Nov 2021

Antigen News and Research

Novel strategy to produce SARS-CoV-2 nucleocapsid protein for serological testing

Toll-like receptor 2 - novel target for improved COVID-19 vaccines

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

Study reveals complex interplay between diet, gut microbiota, and immune function

Long-term Pfizer vaccine-elicited SARS-CoV-2 antibody profile in breast milk

Effect of contact networks on SARS-CoV-2 transmission and control

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

What genes affect the COVID-19 gender imbalance?

Study: Covid-19 vaccine-elicited immune cells persist six months after vaccination

SARS-CoV-2 replicates in human placenta with release of infectious viral particles

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

Myocarditis among Moderna COVID-19 vaccine recipients

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers develop a highly efficient method to generate immune cells for cancer therapies

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

SARS-CoV-2 infection inhibited by CCR2 signaling

Mycobacterium tuberculosis may induce resistance to secondary SARS-CoV-2 infection

NanoTCE technology shows promise for treatment of acute myeloid leukemia

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Regular blood tests can identify prostate cancer patients who are resistant to treatment

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