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Study unravels new clues to cause and treatment of spinal muscular atrophy

Spinal muscular atrophy, a neurodegenerative disease that causes progressive muscle wasting and paralysis, may be partly due to abnormalities in the synapses that connect sensory neurons and motor neurons, according to researchers at Columbia University Medical Center.

16 May 2017

Research could lead to development of new therapies that reduce pathological fear in PTSD

Research published by scientists at the University of California, Riverside on "fear memory" could lead to the development of therapies that reduce the effects of post-traumatic stress disorder (PTSD).

16 May 2017

CUMC researchers create new organoids that mimic features of full-sized lung

New lung "organoids"-tiny 3-D structures that mimic features of a full-sized lung- have been created from human pluripotent stem cells by researchers at Columbia University Medical Center. The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.

11 May 2017

Suppression of thyroid hormone receptor protects cone cells in mouse models of retinal diseases

New research published online in The FASEB Journal suggests that the suppression of thyroid hormone receptor activity locally in the retina protects cone photoreceptor cells in mouse models of human retinal degenerative diseases

11 May 2017

New organoid ‘fusion’ technique helps observe complex interactions between diverse brain regions

In 2013 researchers led by IMBA scientist Jürgen Knoblich flabbergasted the scientific community. Starting from human stem cells, researchers in his lab managed to grow living three dimensional models of basic units of human brain in a dish.

11 May 2017

Light-sheet fluorescence microscopy manufacturer Luxendo acquired by Bruker

Bruker announces that it has acquired Luxendo, a privately held spin-off of the European Molecular Biology Laboratory (EMBL) that develops and manufactures proprietary light-sheet fluorescence microscopy instruments.

From Bruker Nano Surfaces and Metrology 9 May 2017

Drug used to treat bipolar disorder may help prevent brain cell damage in TBI patients

A drug used to treat bipolar disorder and other forms of depression may help to preserve brain function and prevent nerve cells from dying in people with a traumatic brain injury, according to a new Rutgers University study.

8 May 2017

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Columbia University Medical Center researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy.

4 May 2017

Phagocytosis educates the immune system

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation.

4 May 2017

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

10x Genomics, a company focused on enabling the mastery of biology by accelerating genomic discovery, today announced publication of an article in the journal Nature of a collaborative research study with researchers at the Stanford University School of Medicine.

From 10x Genomics, Inc. 4 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

New research begins at University of Warwick to understand cause of brain tumors

A team based at the University's Warwick Medical School will study brain tumor cells in the lab to understand more about the cell division process, and how it can cause cancer when it goes wrong.

2 May 2017

Researchers succeed in generating 3D bioprinted cartilage tissue

A team of researchers at Sahlgrenska Academy has managed to generate cartilage tissue by printing stem cells using a 3D-bioprinter.

28 Apr 2017

Growing mouse tooth provides new understanding of tissue renewal processes

Researchers hope to one day use stem cells to heal burns, patch damaged heart tissue, even grow kidneys and other transplantable organs from scratch.

28 Apr 2017

NETRF announces $4 million in collaborative grants to study neuroendocrine tumors

The Neuroendocrine Tumor Research Foundation today announced its largest research commitment ever -- $4 million in collaborative grants -- most from its new Accelerator Grants program to study neuroendocrine tumors, a widely misunderstood, commonly misdiagnosed cancer type, without adequately identified genomic drivers.

27 Apr 2017

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Regenerative medicine using human pluripotent stem cells to grow transplantable tissue outside the body carries the promise to treat a range of intractable disorders, such as diabetes and Parkinson's disease.

26 Apr 2017

Abnormal levels of specific gut bacteria linked to chronic fatigue syndrome

Scientists at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health have discovered abnormal levels of specific gut bacteria related to chronic fatigue syndrome/myalgic encephalomyelitis, or ME/CFS, in patients with and without concurrent irritable bowel syndrome, or IBS.

26 Apr 2017

Novel mechanism of antidepressant action may benefit patients unresponsive to SSRI treatment

Antidepressants treat symptoms of depression by increasing levels of brain signaling molecules such as serotonin, as with the most widely used type of antidepressant, selective serotonin reuptake inhibitors.

25 Apr 2017

Researchers discover how protein aggregation triggers aging

Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the Universities of Cologne and Bonn has now discovered how protein aggregation affects this genetic program and thus triggers aging.

21 Apr 2017

FAU researchers discover key factor for early metastases in pancreatic cancer

Pancreatic cancer is one of the most aggressive tumour types because it starts forming metastases early. The cancer itself, however, is usually only discovered late. This leads to a high patient mortality rate. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have now discovered why pancreatic cancer and other malignant types of tumours can disseminate so rapidly.

18 Apr 2017

Cell Biology News and Research

Study unravels new clues to cause and treatment of spinal muscular atrophy

Research could lead to development of new therapies that reduce pathological fear in PTSD

CUMC researchers create new organoids that mimic features of full-sized lung

Suppression of thyroid hormone receptor protects cone cells in mouse models of retinal diseases

New organoid ‘fusion’ technique helps observe complex interactions between diverse brain regions

Light-sheet fluorescence microscopy manufacturer Luxendo acquired by Bruker

Drug used to treat bipolar disorder may help prevent brain cell damage in TBI patients

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Phagocytosis educates the immune system

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

Scientists map genetic changes that help drive aggressive brain tumor

New research begins at University of Warwick to understand cause of brain tumors

Researchers succeed in generating 3D bioprinted cartilage tissue

Growing mouse tooth provides new understanding of tissue renewal processes

NETRF announces $4 million in collaborative grants to study neuroendocrine tumors

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Abnormal levels of specific gut bacteria linked to chronic fatigue syndrome

Novel mechanism of antidepressant action may benefit patients unresponsive to SSRI treatment

Researchers discover how protein aggregation triggers aging

FAU researchers discover key factor for early metastases in pancreatic cancer

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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