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C-type lectin receptors play a role in SARS-CoV-2 infection

A new study published on the preprint server bioRxiv in August 2020 confirms and extends earlier findings showing that a type of sugar-based receptor on innate immune cells promotes the entry of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into other cells that carry the viral receptor, angiotensin-converting enzyme 2 (ACE2).

12 Aug 2020

Scientists design new catalyst to widen the range of target chemical substances for radical reactions

Organocatalysts consisting of organic compounds without metal elements are receiving much attention as next generation catalysts in the hope of reducing environmental burden and coping with exhaustion/rising prices of rare metals.

12 Aug 2020

SARS-CoV-2 a "swarm" of mutant viruses

In this new study, the virus was serially passaged in independent cell types in a controlled environment. The researchers found that the virus rapidly adapts to the changing conditions in culture by selecting for pre-existing species.

12 Aug 2020

Natural compund in cedar and grapefruit skin could help repel mosquitoes and ticks says CDC

Over the last few years, there has been a rise in the number of cases of diseases caused by mosquito and tick bites. The U.S. Centers for Disease Control and Prevention (CDC) has said that a natural chemical compound could help combat this problem. This compound Nootkatone is found commonly in cedar trees, and grapefruit skin says the organization.

11 Aug 2020

Bioluminescent molecule in fireflies shines light on mitochondrial activity

The mitochondria provide energy for our cells, yet their role in many diseases is still poorly understood. Thanks to a bioluminescent molecule, scientists at EPFL can observe them at work in living mammals.

10 Aug 2020

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

As COVID-19 continues to take a heavy toll on human health and life in many parts of the world, there is still no effective antiviral drug or vaccine. This has fueled an intensive search for small molecules and proteins that can inhibit viral entry and replication.

10 Aug 2020

Study shows link between high blood lead levels and aberrant methylation of DNA

Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.

7 Aug 2020

High concentrations of toxic pollutants were detected in stranded whales, dolphins

A study led by researchers at Florida Atlantic University's Harbor Branch Oceanographic Institute examined toxins in tissue concentrations and pathology data from 83 stranded dolphins and whales along the southeastern coast of the United States from 2012 to 2018.

7 Aug 2020

Chemists discover a way to create synthetic version of natural anti-cancer compound

Scripps Research chemists Hans Renata, PhD, and Alexander Adibekian, PhD, have discovered a way to efficiently create a synthetic version of a valuable natural compound called cepafungin I, which has shown promise as an anti-cancer agent.

6 Aug 2020

Unique molecular mechanics can pave way for potential treatments for infections

Unique molecular mechanics allowing parasites to thrive in the guts of one billion people open the door to new treatments that are safe for the host.

6 Aug 2020

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps for severe cases of COVID-19.

5 Aug 2020

Drug candidate successfully reversed memory loss in mouse model of Alzheimer's disease

A drug candidate developed by Salk researchers, and previously shown to slow aging in brain cells, successfully reversed memory loss in a mouse model of inherited Alzheimer's disease.

5 Aug 2020

Can Vitamin D help combat the coronavirus?

In a new report published in The Lancet, a team of researchers discussed the possibility that vitamin D could offer protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The meta-analyses of randomized controlled trials performed from 2007 to 2020.

4 Aug 2020

New system monitors, forecasts outbreak risk of dengue, Zika and other Aedes-borne diseases

Researchers led by Columbia University's International Research Institute for Climate and Society and the Pan-American Health Organization have developed a system to monitor and forecast the environmental suitability of transmission of Zika, dengue fever, chikungunya and other diseases carried by species of Aedes mosquitos in the U.S. and neighboring regions.

4 Aug 2020

Specifically designed cyclic peptide inhibitor shown to be active against SARS-CoV-2

A new bioRxiv study by a research group from the University of California Irvine shows in vitro activity and non-toxicity of the first-in-class cyclic peptide that inhibits the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – laying the groundwork for its use in the treatment of coronavirus disease (COVID-19).

4 Aug 2020

Sterile deep well plates

Porvair Sciences offers an extensive range of sterile deep well microplates for sensitive biological and drug discovery applications.

From Porvair Sciences Limited 4 Aug 2020

New research center at University of Warwick to explore the building blocks of childhood

The first building blocks of our lives are to be explored by a new research centre at the University of Warwick, starting from before we are even conceived right up to the age of five years old.

30 Jul 2020

New technique can predict potential preterm birth with 73% accuracy in high-risk women

A new technique that can spot a potential preterm birth in asymptomatic high-risk women, with up to 73% accuracy months before delivery, has been developed by scientists at the University of Warwick.

30 Jul 2020

Scientists develop human lung organoids to study SARS-CoV-2 infection

Now, a new study published on the preprint server bioRxiv in July 2020 reports the development of a human distal lung culture system that can be functionally tested. This will help not only to understand how this infection produces disease but also to test the proliferative capacity of the stem cells in this part of the body.

30 Jul 2020

Study reports highly potent anti-SARS-CoV-2 compounds

A new study published on the preprint server bioRxiv in July 2020 reports that a series of potent enzyme inhibitors have been designed to suppress severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication by interfering with one of the primary viral proteases.

30 Jul 2020

Compound News and Research

C-type lectin receptors play a role in SARS-CoV-2 infection

Scientists design new catalyst to widen the range of target chemical substances for radical reactions

SARS-CoV-2 a "swarm" of mutant viruses

Natural compund in cedar and grapefruit skin could help repel mosquitoes and ticks says CDC

Bioluminescent molecule in fireflies shines light on mitochondrial activity

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

Study shows link between high blood lead levels and aberrant methylation of DNA

High concentrations of toxic pollutants were detected in stranded whales, dolphins

Chemists discover a way to create synthetic version of natural anti-cancer compound

Unique molecular mechanics can pave way for potential treatments for infections

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Drug candidate successfully reversed memory loss in mouse model of Alzheimer's disease

Can Vitamin D help combat the coronavirus?

New system monitors, forecasts outbreak risk of dengue, Zika and other Aedes-borne diseases

Specifically designed cyclic peptide inhibitor shown to be active against SARS-CoV-2

Sterile deep well plates

New research center at University of Warwick to explore the building blocks of childhood

New technique can predict potential preterm birth with 73% accuracy in high-risk women

Scientists develop human lung organoids to study SARS-CoV-2 infection

Study reports highly potent anti-SARS-CoV-2 compounds

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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