Knee News and Research

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Dozens arrested in national Medicare fraud bust

The Associated Press reports: "Federal authorities arrested more than 30 suspects, including doctors, and were seeking others in a major Medicare fraud bust Wednesday in New York, Louisiana, Boston and Houston, targeting scams such as 'arthritis kits' - expensive braces that many patients never used.

30 Jul 2009

Protein level may predict severe osteoarthritis

Osteoarthritis (OA), the most common joint disorder throughout the world and a leading cause of disability, is characterized by pain, impaired joint mobility, reduction of muscular strength and loss of joint function. Unlike most other common diseases, little is known about its origins, and factors predicting a severe disease course have not been identified.

30 Jul 2009

Identification of progressors in osteoarthritis by combining biochemical and MRI-based markers

A combination of biochemical and MRI markers will allow improved measurement of osteoarthritis (OA) progression. The biomarkers, described in BioMed Central's open access journal Arthritis Research and Therapy, will be useful for the design and interpretation of trials of new disease modifying drugs.

23 Jul 2009

Early inflammatory signs of osteoarthritis

Researchers at The University of Nottingham are hoping to find out if inflammation of the knee could be an early sign of osteoarthritis - a condition which leads to pain, stiffness, swelling and disability.

23 Jul 2009

Obesity associated with increased risk of rapid cartilage loss

Obesity, among other factors, is strongly associated with an increased risk of rapid cartilage loss, according to a study published in the August issue of Radiology.

14 Jul 2009

Severe obesity brings greater risks of health problems during medical procedures

Healthcare providers must carefully consider the unique risk factors related to severe obesity in patients undergoing all types of surgery, according to an American Heart Association scientific advisory published in Circulation: Journal of the American Heart Association.

15 Jun 2009

Experimental imaging technique reveals ‘tell tale’ brain plaques in Alzheimer's

Researchers at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have demonstrated a new, highly detailed x-ray imaging technique that could be developed into a method for early diagnosis of Alzheimer's disease.

15 Jun 2009

Researchers examine 'invading' bacteria in DNA - advanced warfare on the most elemental of levels

Researchers at Texas A&M University's Artie McFerrin Department of Chemical Engineering have discovered how certain types of bacteria integrate the DNA that they have captured from invading enemies into their own genetic makeup to increase their chances of survival.

2 Jun 2009

Genomic research lays groundwork for new approaches for treating, preventing skin diseases

The health of our skin - one of the body's first lines of defense against illness and injury - depends upon the delicate balance between our own cells and the millions of bacteria and other one-celled microbes that live on its surface.

28 May 2009

New U.S. patent issued for Limbrel in osteoarthritis

Primus Pharmaceuticals, Inc. has announced the issuance of a new composition of matter patent for Limbrel, the first prescription medical food product to safely meet the distinctive nutritional requirements of patients with osteoarthritis (OA). U.S. Patent #7,514,469 was recently issued by the U.S. Patent and Trademark Office.

27 May 2009

Treating pain with depression

Pain, the most common reason for adults to visit a primary care physician, and depression, the most frequent mental complaint requiring a doctor's appointment, occur together as often as half the time.

26 May 2009

Non-wovens as scaffolds for artificial tissue

When someone's knee hurts with every step it's a sign that the cartilage has been so badly damaged that the bones rub together when walking.

13 May 2009

MRI identifies five causes of complications from ACL reconstructive surgery

MRI has identified five possible causes of patient complications from anterior cruciate ligament (ACL) reconstructive surgery, according to a study performed at Emory University Hospital in Atlanta, GA, and Sahlgrenska-Molndal University Hospital in Gothenborg, Sweden.

23 Apr 2009

First human study of pioneering 'cell bandage' technology

A company co-founded by Professor Anthony Hollander has raised over £1.6 million to fund trials, including the first human study, of its pioneering 'cell bandage' technology, which aims to save thousands of patients from the type of knee surgery that currently leads to premature osteoarthritis.

22 Apr 2009

Menstrual cycle affects knee joints

New research from the Faculty of Kinesiology at the University of Calgary has found a connection between the laxity of a woman's knee joint and her monthly hormone cycle.

20 Apr 2009

New easy to understand guide on treatments for osteoarthritis of the knee

A new pair of plain-language guides from the Agency for Healthcare Research and Quality (AHRQ) examines the effectiveness, safety, and adverse effects of various treatments for osteoarthritis of the knee, including glucosamine and chondroitin, fluid injections, arthroscopic surgery, pain medications and other approaches.

13 Apr 2009

Many clinicians unaware of federally funded research on alternative therapies

Approximately one in four practicing clinicians appear to be aware of two major federally funded clinical trials of alternative therapies, and many do not express confidence in their ability to interpret research results, according to a report in the April 13 issue of Archives of Internal Medicine.

13 Apr 2009

RegeneRx reports phase II venous stasis trial results

Regenerx Biopharmaceuticals Inc. has announced the results of its Phase II clinical trial evaluating the safety and wound-healing efficacy of RGN-137 for the treatment of patients with venous stasis ulcers.

29 Mar 2009

Saving limbs with drug-eluting stents

Attempts to treat critical limb ischemia in peripheral arterial disease (PAD) patients with below-the-knee angioplasty are still thwarted by restenosis (the re-narrowing of the artery at the site of angioplasty or stenting), the need for repeat treatments and the continued progression of atherosclerotic disease, leading to tissue death (gangrene) and amputation.

11 Mar 2009

Metastatic bone disease patients can walk in Lazarus' footsteps

Osteoplasty - a highly effective minimally invasive procedure to treat the painful effects of metastatic bone disease by injecting bone cement to support weakened bones - provides immediate and substantial pain relief, often presenting individuals who are suffering terribly with the miraculous so-called "Lazarus effect," according to researchers at the Society of Interventional Radiology's 34th Annual Scientific Meeting.

10 Mar 2009