Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Kamada announces top-line results from Phase II/III trial for treatment of inherited emphysema

Kamada Ltd., a plasma-derived protein therapeutics company focused on orphan indications, announces preliminary top-line results from the Phase II/III pivotal clinical trial in Europe and Canada of the Company's proprietary inhaled Alpha-1 Antitrypsin (AAT) therapy for the treatment of Alpha-1 Antitrypsin Deficiency (AATD or inherited emphysema).

16 May 2014

Research: Single episode of binge drinking can have negative health effects

It only takes one time. That's the message of a new study by scientists at the University of Massachusetts Medical School on binge drinking. Their research found that a single episode of binge drinking can have significant negative health effects resulting in bacteria leaking from the gut, leading to increased levels of toxins in the blood.

16 May 2014

Albert Einstein College of Medicine hosts second Stem Cell Symposium focusing on cancer stem cells

Healthy stem cells work to restore or repair the body's tissues, but cancer stem cells have a more nefarious mission: to spawn malignant tumors. Cancer stem cells were discovered a decade ago, but their origins and identity remain largely unknown.

14 May 2014

Scientists decrypt interaction network of hepatitis C virus proteins in living human cells

Scientists at the Helmholtz Zentrum München have for the first time decrypted the interaction network of hepatitis C virus proteins in living human cells. Their findings will contribute to a better understanding of the mechanisms behind inflammatory liver disease caused by hepatitis C viruses and open up new avenues for therapy development.

9 May 2014

uEtG accurately detects alcohol consumption in liver transplant candidates and recipients

Researchers from Italy confirm that urinary ethyl glucuronide (uEtG) accurately detects alcohol consumption in liver transplant candidates and recipients.

9 May 2014

Hepatocellular carcinoma on the rise among Mexican Americans

Hepatocellular carcinoma (HCC), the primary cancer of the liver, is on the verge of becoming an epidemic among Mexican Americans, especially in Texas.

8 May 2014

Janssen submits sNDA to FDA for simeprevir in combination with sofosbuvir for treatment of HCV genotype 1 infection

Janssen Research & Development, LLC (Janssen) today announced it has submitted a Supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for simeprevir, an NS3/4A protease inhibitor marketed as OLYSIO™ in the United States, in combination with the nucleotide analog NS5B polymerase inhibitor sofosbuvir developed by Gilead Sciences, Inc.

8 May 2014

Snacking linked with abdominal fat and fatty liver

Researchers from The Netherlands found that snacking on high-fat and high-sugar foods was independently associated with abdominal fat and fatty liver (hepatic steatosis).

7 May 2014

Liver cancer screening in cirrhosis patients improves survival rates

Liver cancer survival rates could be improved if more people with cirrhosis are screened for tumors using inexpensive ultrasound scans and blood tests, according to a review by doctors at UT Southwestern Medical Center.

6 May 2014

Researchers find links between hospital readmission rates and social factors

Factors like the level of poverty in a neighborhood, living alone, and age affect a patient's chances of being readmitted to a hospital after discharge, even after possible variations in quality of care in the hospital have been taken into account.

6 May 2014

Alcohol consumption linked with increased risk of advanced liver fibrosis in HIV patients

Consumption of alcohol has long been associated with an increased risk of advanced liver fibrosis, but a new study published online in Clinical Infectious Diseases from researchers at Penn Medicine and other institutions shows that association is drastically heightened in people co-infected with both HIV and chronic hepatitis C virus (HCV) infection.

5 May 2014

High-dose steroid therapy following surgery do not improve bile drainage among infants

Among infants who underwent surgery to repair bile ducts that do not drain properly (biliary atresia), the administration of high-dose steroid therapy following surgery did not significantly improve bile drainage after 6 months, although a small clinical benefit could not be excluded, according to a study in the May 7 issue of JAMA, a theme issue on child health.

5 May 2014

High doses of steroids fail to improve outcomes in pediatric liver disease

A multi-center study concludes that treating infants with high doses of steroids fails to improve medical outcomes in the end-stage pediatric liver disease biliary atresia and leads to earlier onset of serious adverse events.

5 May 2014

Study shows reversal of early-stage liver fibrosis after bariatric surgery

Bariatric surgery, which is best known for its ability to help patients lose substantial weight, can also result in significant improvement in nonalcoholic fatty liver disease (NAFLD), according to new research presented today at Digestive Disease Week- (DDW).

5 May 2014

Cedars-Sinai director honored for lifetime of achievement in field of liver transplantation

Andrew S. Klein MD, MBA, director of the Cedars-Sinai Comprehensive Transplant Center is being honored for a lifetime of achievement in the field of liver transplantation by the Los Angeles chapter of the American Liver Foundation.

2 May 2014

New data from EMD Serono's multiple sclerosis portfolio to be presented at the 66th AAN Annual Meeting

EMD Serono, Inc., a subsidiary of Merck KGaA, Darmstadt, Germany, announced today that new data from the company's multiple sclerosis (MS) portfolio will be presented at the American Academy of Neurology's 66th Annual Meeting, taking place from April 26 – May 3, in Philadelphia, PA.

26 Apr 2014

Discovery offers potential target for reversing progression of end-stage liver disease

A team of researchers in the University of Arizona's College of Pharmacy has discovered a molecular pathway that could be key to creating new therapeutics that would slow or even reverse the progression of end-stage liver disease.

26 Apr 2014

Lodging fund eases financial burden for Loyola liver disease patients

The hefty cost of a Chicago hotel room is an expected expense for many who are traveling for business or pleasure. But for many Downstate families of Loyola liver patients, the added expense of a hotel room to be near a loved one battling a serious and chronic disease takes a huge financial toll.

23 Apr 2014

New tool can help doctors identify patients at highest risk for respiratory failure after surgery

A new prediction tool can help doctors better identify patients who are at highest risk for respiratory failure after surgery and therefore prevent the often deadly condition, suggest data from a large multi-center study published in the May issue of Anesthesiology.

23 Apr 2014

Cost of Hep C medicines vexing insurers

As health insurance companies reveal much anticipated first-quarter earnings, it's the unpredictable impact from the five-figure cost of new Hepatitis C treatments that are the subject of as much Wall Street worry as the Affordable Care Act.

22 Apr 2014

Liver Disease News and Research

Further Reading

Kamada announces top-line results from Phase II/III trial for treatment of inherited emphysema

Research: Single episode of binge drinking can have negative health effects

Albert Einstein College of Medicine hosts second Stem Cell Symposium focusing on cancer stem cells

Scientists decrypt interaction network of hepatitis C virus proteins in living human cells

uEtG accurately detects alcohol consumption in liver transplant candidates and recipients

Hepatocellular carcinoma on the rise among Mexican Americans

Janssen submits sNDA to FDA for simeprevir in combination with sofosbuvir for treatment of HCV genotype 1 infection

Snacking linked with abdominal fat and fatty liver

Liver cancer screening in cirrhosis patients improves survival rates

Researchers find links between hospital readmission rates and social factors

Alcohol consumption linked with increased risk of advanced liver fibrosis in HIV patients

High-dose steroid therapy following surgery do not improve bile drainage among infants

High doses of steroids fail to improve outcomes in pediatric liver disease

Study shows reversal of early-stage liver fibrosis after bariatric surgery

Cedars-Sinai director honored for lifetime of achievement in field of liver transplantation

New data from EMD Serono's multiple sclerosis portfolio to be presented at the 66th AAN Annual Meeting

Discovery offers potential target for reversing progression of end-stage liver disease

Lodging fund eases financial burden for Loyola liver disease patients

New tool can help doctors identify patients at highest risk for respiratory failure after surgery

Cost of Hep C medicines vexing insurers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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