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Detailed images reveal how regulatory proteins affect function of brain receptors

Scientists at Columbia University have obtained the first detailed images of interactions between the AMPA receptor and molecules that regulate chemical signaling in the brain.

3 May 2017

Lost function of genes impairs development of motor skills in maturing mice

Scientists report in Neuron the lost function of two genes prevents infant laboratory mice from developing motor skills as they mature into adults. Researchers also suggest in their study that people with certain motor development disabilities be tested to see if they have mutant forms of the same genes.

3 May 2017

Researchers uncover new potential target for treating spinal muscular atrophy

Though spinal muscular atrophy in its most severe form remains incurable and fatal in early childhood, researchers are sustaining a multipronged counterattack for patients and their families. The first treatment for the disease gained U.S. market approval in December.

2 May 2017

Researchers create new tool that reveals insights into cellular development

Researchers at Columbia University Medical Center have created a new tool to describe the many possible ways in which a cell may develop. Rooted in the mathematical field of topology, the tool provides a roadmap that offers detailed insight into how stem cells give rise to specialized cells.

2 May 2017

Powerful pain medicine may help reduce vision damage of glaucoma

The tip of our optic nerve is typically the first place injured by glaucoma. Now researchers want to know if the powerful pain medicine (+)-pentazocine can help avoid the damage.

2 May 2017

Newly discovered molecule plays central role in appetite control mechanisms

A newly discovered molecule increases appetite during fasting -- and decreases it during gorging. The neuron-exciting protein, named NPGL - apparently aims to maintain body mass at a constant, come feast or famine. An evolutionary masterstroke, but not great news for those looking to trim down -- or beef up for the summer.

28 Apr 2017

New software wrapper boosts ability of existing neuron tracing algorithms

Putting a turbo engine into an old car gives it an entirely new life--suddenly it can go further, faster. That same idea is now being applied to neuroscience, with a software wrapper that can be used on existing neuron tracing algorithms to boost their ability to handle not just big, but enormous sets of data

27 Apr 2017

Study provides new understanding of molecular mechanisms that impact intellectual disability

Scientists from the Florida campus of The Scripps Research Institute have shown that a protein helps balance nerve cell communication.

25 Apr 2017

Caltech researchers discover brain region that judges intensity, ambiguity of facial expressions

Have you ever thought someone was angry at you, but it turned out you were just misreading their facial expression? Caltech researchers have now discovered that one specific region of the brain, called the amygdala, is involved in making these (sometimes inaccurate) judgments about ambiguous or intense emotions.

25 Apr 2017

Neurobiologists use skin stem cells to generate new microglia

Using human skin cells, University of California, Irvine neurobiologists and their colleagues have created a method to generate one of the principle cell types of the brain called microglia, which play a key role in preserving the function of neural networks and responding to injury and disease.

25 Apr 2017

Synchronized voltage rhythms in SCN could play role in maintaining the body’s circadian clock

Cells in the brain's master circadian clock synchronize voltage rhythms despite asynchronous calcium rhythms, which might explain how a tissue-wide rhythm is maintained.

24 Apr 2017

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Biogen today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion recommending the granting of a marketing authorization for SPINRAZA to treat patients with spinal muscular atrophy (SMA).

21 Apr 2017

UCLA research overturns paradigm about how axons grow during embryonic development

New research by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA overturns a long-standing paradigm about how axons -- thread-like projections that connect cells in the nervous system -- grow during embryonic development.

21 Apr 2017

Johns Hopkins researchers discover group of nerve cells in the skin responsible for ‘active touch’

Working with genetically engineered mice -- and especially their whiskers -- Johns Hopkins researchers report they have identified a group of nerve cells in the skin responsible for what they call "active touch," a combination of motion and sensory feeling needed to navigate the external world.

21 Apr 2017

Researchers reveal promising performance of retinal prosthesis implanted in rats

Researchers at Okayama University report in the Journal of Artificial Organs the promising performance of a retinal prosthesis material when implanted in rats. The material is capable of converting external light stimuli into electric potentials that are picked up by neurons.

21 Apr 2017

CELENA™ S advanced imaging workflow solution released by Logos Biosystems

Logos Biosystems announced the launch of the new CELENA™ S Digital Imaging System with an onstage incubator. The multipurpose CELENA S is designed to simplify high-resolution fluorescence, brightfield, and phase contrast imaging for novices and experts alike.

From Logos Biosystems 20 Apr 2017

TSRI scientists reveal important role of genetics in brain circuits

Scientists at The Scripps Research Institute in La Jolla have revealed new clues to the wiring of the brain. A team led by Associate Professor Anton Maximov found that neurons in brain regions that store memory can form networks in the absence of synaptic activity.

19 Apr 2017

New nanowire technology may serve as platform to screen drugs for neurological diseases

A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail.

11 Apr 2017

Scientists discover new role for autophagosomes in neurodegenerative diseases

Autophagosomes are at the center of attention, at least since the Nobel Prize for Medicine was awarded for research on autophagy in 2016. The much talked about autophagosomes are small membrane vesicles in charge of waste disposal to promote recycling of its components.

11 Apr 2017

Study uncovers novel role for cortical interneurons in coding of spatial information

Researchers from King's College London have discovered a specific class of inhibitory neurons in the cerebral cortex which plays a key role in how the brain encodes spatial information. The findings are published in the journal Nature Neuroscience.

10 Apr 2017

Neuron News and Research

Detailed images reveal how regulatory proteins affect function of brain receptors

Lost function of genes impairs development of motor skills in maturing mice

Researchers uncover new potential target for treating spinal muscular atrophy

Researchers create new tool that reveals insights into cellular development

Powerful pain medicine may help reduce vision damage of glaucoma

Newly discovered molecule plays central role in appetite control mechanisms

New software wrapper boosts ability of existing neuron tracing algorithms

Study provides new understanding of molecular mechanisms that impact intellectual disability

Caltech researchers discover brain region that judges intensity, ambiguity of facial expressions

Neurobiologists use skin stem cells to generate new microglia

Synchronized voltage rhythms in SCN could play role in maintaining the body’s circadian clock

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

UCLA research overturns paradigm about how axons grow during embryonic development

Johns Hopkins researchers discover group of nerve cells in the skin responsible for ‘active touch’

Researchers reveal promising performance of retinal prosthesis implanted in rats

CELENA™ S advanced imaging workflow solution released by Logos Biosystems

TSRI scientists reveal important role of genetics in brain circuits

New nanowire technology may serve as platform to screen drugs for neurological diseases

Scientists discover new role for autophagosomes in neurodegenerative diseases

Study uncovers novel role for cortical interneurons in coding of spatial information

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

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