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SOX2 gene potential therapeutic target for SCLC

Expression of the Sry-related HMG box 2 gene is higher in small-celllung cancer tissue samples than in non-cancerous lung tissue samples, according to findings from a genetic study.

13 Sep 2012

People with family history of certain diseases often underestimate their risk

People with a family history of certain diseases, including heart disease and diabetes, often underestimate their risk for developing them, even after completing a risk assessment and receiving personalized prevention messages, finds a new study in the American Journal of Preventive Medicine.

13 Sep 2012

Sanford-Burnham professor to develop personalized models of inherited heart conditions

The California Institute for Regenerative Medicine (CIRM) has awarded a $1.58 million grant to Huei-Sheng Vincent Chen, Ph.D., associate professor at Sanford-Burnham Medical Research Institute (Sanford-Burnham). Chen's proposal was one of 28 new projects funded as part of CIRM's Basic Biology IV awards program, which supports basic research aimed at increasing our understanding of stem cells and how to work with them.

13 Sep 2012

ICREA researcher updates latest findings in applied epigenetics

The research team led by Manel Esteller, director of the Cancer Epigenetics and Biology Program at the Bellvitge Biomedical Research Institute (IDIBELL), professor of genetics at the University of Barcelona and ICREA researcher, has updated the latest findings in applied epigenetics in a review paper published in Nature Reviews Genetics.

13 Sep 2012

NDC to advance study and treatment of Alzheimer's and other neurodegenerative diseases

The Neurodegeneration Consortium (NDC), a transformative multi-institutional initiative, will advance the study and treatment of Alzheimer's and other neurodegenerative diseases, thanks to an inaugural $25 million gift from the Robert A. and Renee E. Belfer Family Foundation to The University of Texas MD Anderson Cancer Center, Baylor College of Medicine and the Massachusetts Institute of Technology (MIT).

13 Sep 2012

Melbourne researchers develop genetic test to predict risk of autism spectrum disorder

A team of Australian researchers, led by University of Melbourne has developed a genetic test that is able to predict the risk of developing Autism Spectrum Disorder, ASD.

13 Sep 2012

Synthetic biology pioneer wins 2012 Heinz Award

Jay Keasling, a leading authority and pioneer on synthetic biology who has engineered microbial "factories" to manufacture an affordable version of a frontline antimalarial drug and biofuel substitutes for gasoline, diesel and jet fuel, has won a 2012 Heinz Award, which is presented by the Heinz Family Foundation and carries with it a cash prize of $250,000.

13 Sep 2012

ATA, AACE develop new guidelines for diagnosis and treatment of hypothyroidism

New evidence-based guidelines have been released for the diagnosis and treatment of hypothyroidism, a complex disease caused by an underactive thyroid gland that cannot produce enough thyroid hormone.

13 Sep 2012

Parents of infants with cystic fibrosis carriers more likely to receive genetic counseling

Parents of newborns with the sickle cell anemia trait were less likely to receive genetic counseling than parents whose babies are cystic fibrosis carriers, a new study from the University of Michigan shows.

12 Sep 2012

Ethnicity, race affect likelihood of finding suitable unrelated stem cell donors for cancer patients

Researchers at Moffitt Cancer Center and colleagues have published a study describing the greater difficulty in finding matched, unrelated donors for non-Caucasian patients who are candidates for hematopoietic cell transplantation (HCT).

12 Sep 2012

Researchers identify novel genes that make some children cope with malaria

Researchers from Sainte-Justine University Hospital Center and University of Montreal have identified several novel genes that make some children more efficient than others in the way their immune system responds to malaria infection.

12 Sep 2012

Pregnancy exposures may increase risk of breast cancer in multiple generations of offspring

Chemicals or foods that raise estrogen levels during pregnancy may increase cancer risk in daughters, granddaughters, and even great-granddaughters, according to scientists from Virginia Tech and Georgetown University.

12 Sep 2012

APS conference to explore potential mechanisms behind health benefits of exercise

The effects of physical inactivity are, literally, hazardous to your health. Although the detrimental effects of being inactive are generally thought to be associated with childhood obesity and Type 2 diabetes, they have a significant impact on other illnesses. Physical inactivity contributed at least 25 percent to the prevalence of hip fractures, osteoporosis, coronary heart disease, and colon cancer according to recent data released by the U.S. Department of Health and Human Services.

12 Sep 2012

Genetic test predicts risk for Autism

A team of Australian researchers, led by University of Melbourne has developed a genetic test that is able to predict the risk of developing Autism Spectrum Disorder, ASD.

11 Sep 2012

KRAS gene mutation recruits second player to trigger pancreatic cancer

More than a cancer-causing gene is needed to trigger pancreatic cancer, a study led by Mayo Clinic has found. A second factor creates a "perfect storm" that allows tumors to form, the researchers say. The study, published in the Sept. 10 issue of Cancer Cell, overturns the current belief that a mutation in the KRAS oncogene is enough to initiate pancreatic cancer and unrestrained cell growth.

11 Sep 2012

Study discovers pathways that govern instability of GAA/TTC repeats

A study of more than 6,000 genes in a common species of yeast has identified the pathways that govern the instability of GAA/TTC repeats. In humans, the expansions of these repeats is known to inactivate a gene - FXN - which leads to Friedreich's ataxia, a neurodegenerative disease that is currently incurable. In yeast, long repeats also destabilize the genome, manifested by the breakage of chromosomes.

11 Sep 2012

Two different genetic mutations cooperate to induce adrenal cancer

Two different genetic mutations cooperate to induce adrenal cancer, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center and University of Sao Paulo in Brazil.

11 Sep 2012

HIF-1 activity directly responsible for spread of breast cancer to lymph vessels

The invasion of cancer cells into the lymph vessels that connect the breast to surrounding lymph nodes is the first step leading to the metastasis, or spread, of cancer throughout the body. Metastasis is the primary cause of breast cancer deaths. Surprisingly little is known about the control of this process and how it might be interrupted to prolong the lives of women with breast cancer.

11 Sep 2012

New computer system interprets human emotions based on lip pattern

A computer is being taught to interpret human emotions based on lip pattern, according to research published in the International Journal of Artificial Intelligence and Soft Computing. The system could improve the way we interact with computers and perhaps allow disabled people to use computer-based communications devices, such as voice synthesizers, more effectively and more efficiently.

11 Sep 2012

HIV viruses with two genetic 'footprints' associated with greater vaccine efficacy

Scientists used genetic sequencing to discover new evidence that the first vaccine shown to prevent HIV infection in people also affected the viruses in those who did become infected. Viruses with two genetic "footprints" were associated with greater vaccine efficacy. The results were published today in the online edition of the journal Nature.

10 Sep 2012

Genetic News and Research

SOX2 gene potential therapeutic target for SCLC

People with family history of certain diseases often underestimate their risk

Sanford-Burnham professor to develop personalized models of inherited heart conditions

ICREA researcher updates latest findings in applied epigenetics

NDC to advance study and treatment of Alzheimer's and other neurodegenerative diseases

Melbourne researchers develop genetic test to predict risk of autism spectrum disorder

Synthetic biology pioneer wins 2012 Heinz Award

ATA, AACE develop new guidelines for diagnosis and treatment of hypothyroidism

Parents of infants with cystic fibrosis carriers more likely to receive genetic counseling

Ethnicity, race affect likelihood of finding suitable unrelated stem cell donors for cancer patients

Researchers identify novel genes that make some children cope with malaria

Pregnancy exposures may increase risk of breast cancer in multiple generations of offspring

APS conference to explore potential mechanisms behind health benefits of exercise

Genetic test predicts risk for Autism

KRAS gene mutation recruits second player to trigger pancreatic cancer

Study discovers pathways that govern instability of GAA/TTC repeats

Two different genetic mutations cooperate to induce adrenal cancer

HIF-1 activity directly responsible for spread of breast cancer to lymph vessels

New computer system interprets human emotions based on lip pattern

HIV viruses with two genetic 'footprints' associated with greater vaccine efficacy

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