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Mutations in the insulin gene can cause permanent neonatal diabetes

Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections, report researchers from the University of Chicago and Peninsula University (Exeter, UK) in Sept. 18, 2007, issue of the Proceedings of the National Academy of Sciences, published early online.

11 Sep 2007

Coding and noncoding genes are involved in and cooperate in human tumorigenesis

A new study provides evidence that noncoding RNAs and interactions between noncoding genes play a much greater role in human cancer than was previously understood.

11 Sep 2007

Novel enzyme may offer huge range of potential therapeutic agents

By guiding an enzyme down a new evolutionary pathway, a team of University of Wisconsin-Madison researchers has created a new form of an enzyme capable of producing a range of potential new therapeutic agents with anticancer and antibiotic properties.

10 Sep 2007

Genetic causes of rheumatoid arthritis

The human genome has now been thoroughly screened in the hunt for the genetic causes of rheumatoid arthritis. The results, which both confirms previous hypotheses and turn the spotlight on entirely new genes, are presented in two articles in the prestigious New England Journal of Medicine.

10 Sep 2007

New genetic risk factor for rheumatoid arthritis and lupus

A genetic variation has been identified that increases the risk of two chronic, autoimmune inflammatory diseases: rheumatoid arthritis (RA) and systemic lupus erythematosus (lupus).

10 Sep 2007

Researchers make new discovery on pigment melanin and skin - hair color

The pigment melanin, which is responsible for skin and hair color in mammals, is produced in specialized cells called melanocytes and then distributed to other cells. But not every cell in the complex layers of skin becomes pigmented.

10 Sep 2007

Research looks at prions and retroviruses

National Research Center for Environment and Health in Neuherberg/Munich (Helmholtz Association of German Research Centres) the group is continuing to search for cellular components whose make-up is changed as a result of a prion infection.

10 Sep 2007

Clearer picture of how a dividing cell rebuilds the nuclear envelope

Just how a dividing cell rebuilds the nuclear envelope, the protective, functional wrapping that encases both the original and newly copied genetic material, has been a source of controversy for the last 20 years.

10 Sep 2007

Safer gene therapy - biodegradable polymers to deliver genes

In work that could lead to safe and effective techniques for gene therapy, MIT researchers have found a way to fine-tune the ability of biodegradable polymers to deliver genes.

10 Sep 2007

A chink in bacteria's armor

Biomedical researchers at Boston University's College of Engineering may have discovered the path toward developing better drugs capable of defeating so-called “superbugs,” bacteria that have developed resistance to common antibiotics. The researchers have discovered a previously unknown chain of events occurring in bacteria that opens to door to new avenues of research.

10 Sep 2007

Racial disparities in prostate cancer, why?

African-American men face a higher risk of developing prostate cancer in their lifetime, but researchers do not fully understand why.

5 Sep 2007

Ultraconserved elements in the genome: Are they indispensable?

Three years ago, "ultraconserved elements" were discovered in the genomes of mice, rats, and humans.

5 Sep 2007

Antiobesity gene

Researchers have revealed an antiobesity gene that has apparently been keeping critters lean during times of plenty since ancient times.

5 Sep 2007

Adipose gene may be the key to tackle weight

Researchers at UT Southwestern Medical Center have found that a single gene might control whether or not individuals tend to pile on fat, a discovery that may point to new ways to fight obesity and diabetes.

5 Sep 2007

Selection on genes underlying schizophrenia during human evolution

Several genes with strong associations to schizophrenia have evolved rapidly due to selection during human evolution, according to new research in the Proceedings of the Royal Society B (Wednesday 5 September 2007).

5 Sep 2007

Quick microchip test for dangerous and drug resistant bacteria in clinical samples

Researchers at the Veterinary Laboratories Agency in Surrey have developed microchips capable of quickly and cheaply identifying dangerous and drug resistant bacteria in clinical samples, scientists announced (Wednesday 5 September 2007) at the Society for General Microbiology's 161st Meeting at the University of Edinburgh, UK, which runs from 3-6 September 2007.

5 Sep 2007