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New research reveals a hidden source of cellular bioelectricity

Many biological processes are regulated by electricity-from nerve impulses to heartbeats to the movement of molecules in and out of cells.

19 Dec 2025

Hidden kinase state enables rapid and repeated protein phosphorylation

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its target, without needing to release and reattach to the target each time.

19 Dec 2025

Mitochondria shift toward the cell edge in response to glucose

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear.

19 Dec 2025

New grant supports research into drug-induced brain toxicity

Important FDA-approved drugs to treat HIV and cancer can save lives, but they come with their own risks. Some drugs used clinically are known to cause neurological side effects in up to half of patients, ranging from confusion and memory problems to permanent nerve damage.

19 Dec 2025

New insights into how a molecular gatekeeper controls early protein modification

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have now discovered that this complex also contributes a crucial function in ensuring that our DNA is properly processed and “packaged”.

19 Dec 2025

Long-approved drug shows promise in slowing neuron loss in Alzheimer’s disease

Scientists at the University of Colorado Anschutz have discovered that while brain neuron changes, including cell loss, may begin in early life, a drug long-approved for other conditions might be repurposed to slow this damage, offering new hope for those with Alzheimer's disease (AD) and other cognition issues.

19 Dec 2025

DNA twisting controls how cells respond to estrogen

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the body changes so much during menopause. This is because estrogens regulate hundreds of genes.

19 Dec 2025

Viral DNA elements help control early embryonic development

Transposable elements are stretches of DNA that can move around the genome. Many of these DNA sequences originate from long ago, when viruses inserted their genetic material into our ancestors' genomes during infection.

19 Dec 2025

Study identifies TAK1 gene as a key brake on cancer immunotherapy

Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.

19 Dec 2025

Cutting carbs, not fat, may better control appetite in women

Research indicates low-carb diets may enhance appetite regulation and reduce food cues in women with lipedema, offering a dietary intervention advantage.

19 Dec 2025

Autophagy steers T cell fate during immune division

Researchers at the Max Delbrück Center have found that a cellular housekeeping mechanism called autophagy plays a major role in ensuring that T stem cells undergo normal cell division.

19 Dec 2025

Genes and biological networks that drive long COVID risk

This study merges causal genetics and network theory, revealing 32 genes linked to long COVID, offering insights for diagnostics and personalized therapies.

19 Dec 2025

CHITOSE and FUJIFILM Biosciences form strategic alliance to drive global innovation and biopharmaceutical manufacturing

Chitose Laboratory Corp., (CHITOSE), a leading company of the bioeconomy and provider of advanced cell line development services, and FUJIFILM Biosciences Inc., a global leader in the innovation and manufacture of cell culture solutions for the life science market, today announced a new strategic alliance that leverages the strengths of both companies in advancing biopharmaceutical production.

18 Dec 2025

Researchers provide a global catalog of human pluripotent stem cell lines for clinical use

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental pipelines.

18 Dec 2025

New tear gland organoids shed light on the biology of dry eye disease

An estimated 5-15% of people have problems with dry eyes, with symptoms including eye redness, stinging, or burning sensation, and eye fatigue. Dry eye disease (DED) occurs when the eyes' tear glands produce insufficient or poor-quality tears which can be due to allergy or autoimmune disease, hormonal changes, aging, etc.

18 Dec 2025

How diabetes medications may influence cancer risk and progression

Diabetes, particularly Type 2 Diabetes (T2DM), has been linked to an increased risk of various cancers, including liver, colorectal, and breast cancer.

18 Dec 2025

Phages use small RNA to hijack bacterial cells and boost replication

As antibiotic-resistant infections rise and are projected to cause up to 10 million deaths per year by 2050, scientists are looking to bacteriophages, viruses that infect bacteria, as an alternative.

18 Dec 2025

Estrogen drives gut pain and explains higher rates of IBS in women

Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort.

18 Dec 2025

Researchers point to mitochondria as a missing link between mental health and brain function

A stressful year leads to anxiety. Lasting isolation gives way to depression. An old trauma nags until it becomes paralyzing.

18 Dec 2025

New nanoparticle vaccines show promise against multiple deadly filoviruses

Filoviruses get their name from the Latin word "filum," meaning thread-a reference to their long, filamentous shape. This virus family contains some of the most dangerous pathogens known to science, including Ebola, Sudan, Bundibugyo and Marburg viruses.

18 Dec 2025