Brain Cancer News and Research

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There are two main types of brain cancer. Primary brain cancer starts in the brain. Metastatic brain cancer starts somewhere else in the body and moves to the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Also called glioma, meningioma.

Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA - loops of DNA found outside of regular chromosomes - are twice as likely to relapse and three times as likely to die within five years of diagnosis.

14 Nov 2023

Cancer neuroscience: A new frontier in cancer treatment

Cancer cells hijack normal biological processes, allowing them to multiply. For example, tumors spur construction of new blood vessels, building themselves "highways" to supply nutrients.

1 Nov 2023

UniSA seeks public support for vital research on deadly brain cancers

The University of South Australia is seeking public support for vital brain cancer research that could potentially save hundreds of lives.

31 Oct 2023

Researchers receive €10.6 million to develop new therapeutic approaches to target glioblastoma

Researchers at the Universities of Amsterdam and Leiden together with the Netherlands Cancer Institute (Amsterdam) and Oncode Institute (Utrecht) have received a €10.6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma, a deadly primary brain tumor for which no curing therapy is yet available.

26 Oct 2023

Anti-anxiety drug can improve the effectiveness of chemo-radiotherapy towards glioblastoma

A new research study shows that cerebrospinal fluid reduces current treatment efficacy in brain cancer and identifies new therapeutic opportunities.

25 Oct 2023

Does inflammatory bowel disease have a causal relationship with extracolonic tumors?

Whether inflammatory bowel disease (IBD) is causally related to extracolonic cancers.

17 Oct 2023

Study suggests a potential strategy to combat aggressive brain tumors

A new study has unraveled a crucial link between how cancer cells cope with replication stress and the role of Taurine Upregulated Gene 1 (TUG1). By targeting TUG1 with a drug, the researchers were able to control brain tumor growth in mice, suggesting a potential strategy to combat aggressive brain tumors such as glioblastomas.

12 Oct 2023

New zebrafish xenograft platform could help screen for glioblastoma treatments

Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study by the Gerhardt and De Smet labs published in EMBO Molecular Medicine.

4 Oct 2023

MR-linac systems could help clinicians distinguish true progression from pseudoprogression in glioblastoma

Is it true progression or pseudoprogression in tumor growth?

3 Oct 2023

Study details the key role played by neutrophils in ensuring survival of brain cancers

A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.

27 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

Adaptive platform trial shows promise for finding new glioblastoma therapies

An innovative phase 2 clinical trial led by Dana-Farber Cancer Institute in collaboration with 10 major brain tumor centers around the country and designed to find new potential treatments for glioblastoma has reported initial results in the Journal of Clinical Oncology. While none of the three therapeutics tested so far improved overall survival of patients, this adaptive platform trial, the first of its kind in neuro-oncology, has the potential to rapidly and efficiently identify therapies that benefit patients.

19 Sep 2023

Harnessing the extraordinary capabilities of bio-nanoantennae to target and kill brain tumors

Researchers have discovered a new way to target and kill cancer cells in hard-to-treat brain tumors using electrically charged molecules to trigger self-destruction, that could be developed into a spray treatment used during surgery.

14 Sep 2023

NIH awards $3.2 million to study how unique DNA circles drive deadly pediatric brain tumors

Lukas Chavez, Ph.D., has received $3.2 million from the National Institutes of Health to study how unique DNA circles found in cancer cells drive deadly pediatric brain tumors.

14 Sep 2023

People who require specialized neurologic care most often travel long distances, study finds

Nearly one in five people on Medicare travel 50 or more miles one way to see a neurologist, a doctor who diagnoses and treats diseases of the brain and nervous system, according to research published in the September 13, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

13 Sep 2023

Study reveals a new potential treatment approach for glioblastoma

The discovery of a previously unknown molecular target has inspired what may become a therapeutic breakthrough for people with glioblastoma, the most common and aggressive brain cancer.

11 Sep 2023

‘Like a Russian roulette’: US military firefighters grapple with unknowns of PFAS exposure

A U.S. military firefighter for 32 years, Kurt Rhodes trained and performed his duties with aqueous film forming foam, or AFFF — a highly effective fire suppressant that he never knew contained PFAS chemicals, now known to be harmful to human health.

7 Sep 2023

Researchers receive $2.5 million award to develop a tailored treatment for glioblastoma

A multidisciplinary team of investigators from the UCLA Jonsson Comprehensive Cancer Center was awarded a $2.5 million Translational Team Science Award from the Department of Defense to develop a tailored treatment for glioblastoma, a deadly brain tumor with limited treatment options.

5 Sep 2023

New research could help improve the effectiveness of immunotherapy for people with brain tumors

A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does not.

1 Sep 2023

Salk scientists find new immunotherapy treatment for glioblastoma

Glioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous tendrils into the brain that make surgical tumor removal extremely difficult or impossible.

11 Aug 2023