Creutzfeldt Jakob Disease News and Research

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Creutzfeldt–Jakob disease or CJD (sometimes incorrectly referred to as mad cow disease) is a degenerative neurological disorder (brain disease) that is incurable and invariably fatal. It is the most common among the types of transmissible spongiform encephalopathy found in humans.

New discovery boosts basic understanding of prion infections

Brittleness is often seen as a sign of fragility. But in the case of infectious proteins called prions, brittleness makes for a tougher, more menacing pathogen.

28 Jun 2006

New human genotype may be prone to vCJD

A small study in the British Medical Journal suggests a new human genotype may be prone to variant Creutzfeldt-Jakob disease (vCJD).

6 Jun 2006

vCJD may have infected far more people than previously thought

Scientists at the National CJD Surveillance Unit at the University of Edinburgh say that thousands may be infected with variant Creutzfeldt-Jakob Disease (vCJD) without showing signs or symptoms.

21 May 2006

Transplanted human tissue linked to seven cases of Creutzfeldt-Jakob disease in the UK

Seven cases of Creutzfeldt-Jakob disease (CJD) associated with transplanted human tissue have occurred in the UK over a period of 33 years, reveals a study published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry.

25 Apr 2006

Increase in variant Creutzfeldt Jakob Disease predicted

According to the latest research far more people may be at risk of contracting variant Creutzfeldt Jakob Disease (vCJD) than previously thought.

28 Mar 2006

Third U.S. case of mad cow disease

According to the U.S. Department of Agriculture routine tests have revealed a third U.S. case of mad cow disease.

13 Mar 2006

Research suggests that a common mechanism may underlie a variety of protein folding diseases

Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.

16 Feb 2006

Emerging infectious agents pose new risks for people with bleeding disorders

An international team of scientists, including a hematologist from Thomas Jefferson University in Philadelphia, has concluded that people with bleeding disorders such as hemophilia remain at risk from emerging infectious agents in plasma and blood transfusions. For this reason, recombinant therapies, that is, those produced in the laboratory, must always be an option

16 Feb 2006

Deer a possible source of "mad cow like" disease

A University of Kentucky researcher has warned that eating deer could put people at risk of a disease similar to bovine spongiform encephalopathy (BSE) commonly known as mad cow disease.

30 Jan 2006

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia

Most people with a rare type of dementia called primary progressive aphasia (PPA) have a specific combination of prion gene variants, a new study shows.

28 Nov 2005

MRC study to monitor Pentosan Polysulphate as a treatment for Creutzfeldt-Jakob disease receives approval

The plans for a monitoring study on patients being treated with Pentosan Polysulphate (PPS) for CJD and variant CJD have received a favourable opinion from the Eastern Multi-Centre Research Ethics Committee. This follows a provisional opinion from the committee in August.

19 Sep 2005

Scientists characterize the most infectious prion protein particles

A new study of prions - apparently malformed proteins that initiate deadly brain diseases such as Creutzfeldt-Jakob disease in humans - has yielded surprising information about how the size of prions relates to their infectivity.

10 Sep 2005

Adlyfe receives award from the development of blood test for animal prion diseases

Adlyfe, Inc., a privately held biotech company headquartered in Rockville, MD, focused on early diagnostics for animal and human brain diseases announced the award today of a $650,000 two year grant from the Department of Environment, Food and Rural Affairs (DEFRA) in the UK for continued development of a sensitive early blood test for animal prion diseases.

7 Sep 2005

India could be the source of Mad Cow disease

According to British scientists, Mad Cow disease may have originated from animal feed contaminated with human remains washed ashore after being floated down river in Indian funerals.

5 Sep 2005

New method can detect 'mad cow' proteins in blood

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have found a way to detect the malformed proteins in blood that cause "mad cow disease".

29 Aug 2005

Six possible cases of Creutzfeldt-Jakob disease in Idaho sets alarm bells ringing

According to Idaho officials one case of Creutzfeldt-Jakob disease has been confirmed, and they are investigating five other suspected cases in the state.

14 Aug 2005

New surgical cleaning process reduces risk of vCJD

Scientists say a new cleaning process will reduce the risk of hospital transmission of the human form of mad cow disease.

4 Aug 2005

Three cases of mad cow disease in UK from donated blood

Health officials in the UK are warning blood donors that three patients developed the human form of mad cow disease after receiving blood from a possible one hundred people, some of whom are suspected of carrying the deadly agent.

21 Jul 2005

1980's brain surgery may have exposed 50 patients to Creutzfeldt-Jakob Disease

It has now been revealed that as many as 50 patients may have been exposed to Creutzfeldt-Jakob Disease (CJD) following brain surgery during the 1980s.

31 May 2005

Faulty folding of protein in the environment may cause disease

Serious diseases like Alzheimer's and type-2 diabetes have been shown to be related to unhealthy protein chains that occur when proteins fold incorrectly. In an article in the scientific journal Proceedings of the National Academy of Science, PNAS, a research team directed from Uppsala University shows that similar protein chains in our environment may hasten the process.

4 May 2005