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Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Oregon Health & Science University researchers and partners are developing what could become the first-ever treatment against the debilitating joint pain that can last months or years after becoming infected with the emerging Chikungunya virus.

9 Dec 2022

Addition of capivasertib to fulvestrant doubles progression-free survival in HR-positive breast cancer patients

In patients with hormone receptor (HR)-positive, HER2-negative tumors resistant to aromatase inhibitors, addition of the investigational AKT inhibitor capivasertib to fulvestrant (Faslodex) doubled the median progression-free survival compared with placebo plus fulvestrant in the phase III CAPItello-291 clinical trial, according to results presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

Study shows only 75.8% of children under 15 have antibodies against measles

A study conducted in Brazil and reported in an article in Vaccines shows that in the São José do Rio Preto region in the northwest of São Paulo state, only 75.8% of children aged 0-15 have antibodies against measles.

1 Dec 2022

New evidence of mpox virus transmission before onset of symptoms

Researchers extensively followed-up high-risk contacts of clade IIb mpox (MPX) virus (MPXV)-infected patients to evaluate the risk of MPX after MPXV exposure and to characterize early MPXV infections.

30 Nov 2022

Monkeypox renamed "mpox" in an effort to combat stigma

WHO announces that the monkeypox virus will now be referred to as “mpox” in an effort to reduce the stigmatization of this condition.

29 Nov 2022

Small UK study investigates the effectiveness of a single MVA-BN dose against mpox disease

Researchers estimated the single-dose MVA-BN vaccine effectiveness against symptomatic mpox among high-risk gay, bisexual and other men who have sex with men in England.

29 Nov 2022

Study shows no undetected monkeypox virus transmission before May 2022 in Rotterdam and Amsterdam

Researchers investigated whether undetected human monkeypox virus transmission occurred before Rotterdam and Amsterdam's first documented monkeypox cases.

23 Nov 2022

Shingles linked with higher long-term risk of major cardiovascular event

A new study by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, demonstrated that shingles, also known as herpes zoster, is associated with an almost 30% higher long-term risk of a major cardiovascular event such a stroke or heart attack.

22 Nov 2022

Remdesivir appears to make a big difference in Japanese patients with COVID-19

The COVID-19 pandemic has led to an explosion of clinical research resulting in the development of a variety of vaccines and treatments, although the efficacy of some remains controversial.

22 Nov 2022

World Antimicrobial Awareness Week 2022: The problem of antimicrobial resistance in combating sepsis

As part of World Antimicrobial Resistance Week 2022, News-Medical speaks to Dr. Catharina Hartman, a trustee of the charity Sepsis Research FEAT, about the problems associated with combating sepsis brought on by antimicrobial resistance.

20 Nov 2022

Study concludes monkeypox virus is readily detected by qPCR using three clinically validated assays

Researchers validated monkeypox virus (MPXV) quantitative polymerase chain reaction (qPCR) assays.

17 Nov 2022

Black, Hispanic MSM disproportionately affected by monkeypox

A recent study published in the Morbidity and Mortality Weekly Report described the epidemiologic characteristics of the monkeypox (MPX) outbreak in the United States (US).

15 Nov 2022

Oral deucravacitinib shows promise in patients with active lupus

Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus.

14 Nov 2022

Monkeypox: Painful, itchy skin lesions localized in the genital region

In the setting of the current monkeypox outbreak it is important to consider different clinical courses. This includes skin changes/lesions that are primarily localized at the presumed inoculation sites, a low exanthematous component, and onset of general symptoms only over the course if the illness.

4 Nov 2022

What is the correlation between specific COVID-19 clinical characteristics and anti-SARS-CoV-2 antibody titers?

Researchers investigated the associations between clinical characteristics of coronavirus disease 2019 (COVID-19) and immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

3 Nov 2022

Extensive European study finds very high rates of long-COVID

In a recent study published by the European Center for Disease Prevention and Control, researchers assessed the prevalence of post-coronavirus disease 2019 (COVID-19) condition symptoms.

1 Nov 2022

The serial interval and incubation period for symptom and rash onset for monkeypox virus infection during the current US outbreak

Researchers estimated the serial interval and incubation period of monkeypox virus (MPXV) infections for the 2022 disease outbreak in the United States (US).

1 Nov 2022

New report on the impact of monkeypox on people with HIV

Researchers describe the presentation of patients severely infected with the monkeypox virus.

30 Oct 2022

'What pediatricians need to know' about monkeypox in children

Children aged 8 years or younger should be considered a group at high risk for more severe monkeypox disease, reports The Pediatric Infectious Disease Journal, the official journal of The European Society for Paediatric Infectious Diseases.

28 Oct 2022

CU Anschutz study details the mechanisms behind the link between shingles and strokes

Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according to new research from the University of Colorado Anschutz Medical Campus.