Membrane News and Research

RSS

SARS-CoV-2 fusion peptides play distinct roles according to neutron scattering

A new study determines the physical and thermodynamic events associated with the interactions that lead to the fusion between SARS-CoV-2 and the host.

5 Sep 2021

Temperature variations could have driven the division of protocells

A simple mechanism could underlie the growth and self-replication of protocells - putative ancestors of modern living cells - suggests a study publishing September 3 in Biophysical Journal.

4 Sep 2021

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier.

3 Sep 2021

Lysis Buffer for High Yield Enzymatic Shearing

Porvair Sciences reports how its Chromatrap® Lysis buffer for enzymatic shearing provides users with a complete lysis buffer for the disruption of nuclear cell membranes with a milder detergent than that required for mechanical fragmentation.

From Chromatrap® - Porvair Sciences Ltd 3 Sep 2021

Study suggests a biological basis behind instantaneous compatibility reaction

Have you ever met someone you instantly liked, or at other times, someone who you knew immediately that you did not want to be friends with, although you did not know why?

2 Sep 2021

Rheumatoid arthritis drug plus standard of care may reduce COVID-19 mortality for hospitalized patients

Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week in The Lancet Respiratory Medicine.

1 Sep 2021

Growing use of mechanical circulatory support causes moral distress among clinicians

The growing use of mechanical circulatory support (MCS) may contribute to high levels of moral distress for clinicians who regularly care for critically ill patients receiving the aggressive but life-sustaining therapy, according to a study in American Journal of Critical Care.

1 Sep 2021

First pharmacological treatment option for patients with a severe form of epilepsy

Epilepsy comes in a variety of forms. Those affected by a genetically de- termined variety have severe epileptic seizures as early as the first year of life.

1 Sep 2021

Defined & Controllable Extracellular Matrix for Cell Culture

Biochemically defined and animal-free - Mussel Adhesive Protein based matrix (MAPtrix™) from AMSBIO provides a highly defined and controllable recombinant extracellular matrix (ECM) for cell culture, which can be tailored to the specific needs of particular cell types.

From AMS Biotechnology 1 Sep 2021

Structure-based model of SARS-CoV-2 spike protein reveals opportunity to halt virus transmission

Scientists have simulated the transition of the SARS-CoV-2 spike protein structure from when it recognizes the host cell to when it gains entry, according to a study published today in eLife.

1 Sep 2021

Researchers show how a protein molecular motor can 'constrict' cell membranes

Cells in the human body constantly receive substances from the outside via a process called endocytosis. One important endocytosis pathway involves the formation of a protrusion within the cell membrane, pointing to the inside of the cell, triggered when a molecule needing to get in reaches the membrane.

31 Aug 2021

Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

A new study published in mBio investigates the impact of the furin cleavage site on viral growth and pathogenesis.

31 Aug 2021

Finding the genetic cause of childhood epilepsy helps improve treatment and care

Epilepsy is one of the most common chronic neurological diseases, affecting more than 50 million people worldwide. Although it is believed that a large proportion of childhood-onset epilepsies are caused by genetic changes, it remains unknown precisely how many of these patients suffer from a genetic disorder and how often the treatment can be targeted to their specific genetic alteration.

31 Aug 2021

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

A team of investigators, led by Dr. Benjamin F. Mann, from Merck, USA have published a new study on the preprint server bioRxiv*. They have used a biochemical approach to control the glycosylation profile of the S protein receptor-binding domain (RBD) and to analyze the effect of different glycosylation patterns on receptor binding.

30 Aug 2021

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

A new study published in Scientific Reports identifies the human proteins that share structural similarities with the SARS-CoV-2 proteins.

30 Aug 2021

Development of extra protective broad-spectrum antimicrobial face shield

In a new study available on the preprint server Preprints*, researchers have innovated a transparent face shield with intrinsic antimicrobial activity.

30 Aug 2021

SARS-CoV-2 destabilizes host RNA to improve fitness

In a study recently published in the journal Nature Communications, scientists have mapped the interactions between SARS-CoV-2 RNA and host RNA. They have observed that the virus heavily methylates its genome using the methylation machinery of the host RNA, leading to an improvement in viral fitness.

27 Aug 2021

Unconventional T cell and inflammation levels in COVID-19 during pregnancy

A new study published on the medRxiv* preprint server has focused on investigating SARS-CoV-2 immune responses in pregnant women

25 Aug 2021

UC San Diego Health performed region’s first double lung transplant for a COVID-19 patient

On a July afternoon, Federico Gomez Gil, 56, is dressed in a short-sleeved, collared shirt, sweatpants and a baseball cap. He sits in a chair in a hospital room, surrounded by his wife and two daughters. Given the past five months, this is the moment of a lifetime — a new lifetime.

24 Aug 2021

Study suggests a balanced approach to developing safer opioid analgesics

Opioids are powerful painkillers but their use is hindered because patients become tolerant to them, requiring higher and higher doses, and overdoses can cause respiratory depression and death.

24 Aug 2021

Membrane News and Research

SARS-CoV-2 fusion peptides play distinct roles according to neutron scattering

Temperature variations could have driven the division of protocells

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

Lysis Buffer for High Yield Enzymatic Shearing

Study suggests a biological basis behind instantaneous compatibility reaction

Rheumatoid arthritis drug plus standard of care may reduce COVID-19 mortality for hospitalized patients

Growing use of mechanical circulatory support causes moral distress among clinicians

First pharmacological treatment option for patients with a severe form of epilepsy

Defined & Controllable Extracellular Matrix for Cell Culture

Structure-based model of SARS-CoV-2 spike protein reveals opportunity to halt virus transmission

Researchers show how a protein molecular motor can 'constrict' cell membranes

Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

Finding the genetic cause of childhood epilepsy helps improve treatment and care

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

Development of extra protective broad-spectrum antimicrobial face shield

SARS-CoV-2 destabilizes host RNA to improve fitness

Unconventional T cell and inflammation levels in COVID-19 during pregnancy

UC San Diego Health performed region’s first double lung transplant for a COVID-19 patient

Study suggests a balanced approach to developing safer opioid analgesics

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo