Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Researchers develop new technique to map interactions between proteins at heart of many diseases

Researchers at the UNC School of Medicine have devised a new biochemical technique that will allow them and other scientists to delve much deeper than ever before into the specific cellular circuitry that keeps us healthy or causes disease.

10 Mar 2014

Exposure to UV light may exacerbate melanoma cells to creep outside blood vessels

Based on the pioneering work of Dr. Claire Lugassy and Dr. Raymond Barnhill at UCLA's Jonsson Comprehensive Cancer Center, a new study provides additional support for a process by which melanoma cells, a deadly form of skin cancer, can spread throughout the body by creeping like tiny spiders along the outside of blood vessels without ever entering the blood stream, and that this process is exacerbated by exposure to ultraviolet (UV) light.

10 Mar 2014

Agendia co-founder to be honored with 2014 European Union Prize for Women Innovators

Agendia co-founder Laura van 't Veer, Ph.D., will receive a 2014 European Union Prize for Women Innovators in ceremonies next Monday. Dr. van 't Veer, of the Netherlands, is the inventor of Agendia's MammaPrint® breast cancer test.

7 Mar 2014

Verastem presents preliminary data from VS-6063 Phase 1 trial in Japanese patients with solid tumors

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, today presented preliminary data from an ongoing First-in-Asia Phase 1 trial of VS-6063 in Japanese patients with advanced solid tumors, including one patient with mesothelioma. The Phase 1 study assessed the safety and pharmacokinetics of single agent VS-6063.

5 Mar 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

A combination of iron-oxide nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth-Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.

5 Mar 2014

Blocking myoferlin gene can reduce breast cancer cell migration

New research suggests that a protein only recently linked to cancer has a significant effect on the risk that breast cancer will spread, and that lowering the protein's level in cell cultures and mice reduces chances for the disease to extend beyond the initial tumor.

4 Mar 2014

Research provides insight into biologic mechanisms that individual cancer cells use to metastasize to brain

New research from Memorial Sloan Kettering provides fresh insight into the biologic mechanisms that individual cancer cells use to metastasize to the brain.

4 Mar 2014

Researchers discover that carbohydrates serve as identifiers for cancer cells

Researchers at New York University and the University of Texas at Austin have discovered that carbohydrates serve as identifiers for cancer cells. Their findings, which appear in the journal Proceedings of the National Academy of Sciences, show how these molecules may serve as signals for cancer and explain what's going on inside these cells, pointing to new ways in which sugars function as a looking glass into the workings of their underlying structures.

4 Mar 2014

Sunburn causes melanoma through direct and indirect processes

Melanoma is particularly dangerous because it can form metastases in vital organs such as the lungs, liver or brain. UV radiation is considered to be the most significant triggering factor.

3 Mar 2014

NCI recommends renewal for Wistar's Support Grant with award of $14.9M

After an extensive review by a panel of top cancer experts, the National Cancer Institute (NCI) rated The Wistar Institute Cancer Center as "exceptional" and recommended renewal for Wistar's Support Grant with an award of $14.9 million over the next five years.

24 Feb 2014

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Patients with HPV-positive squamous cell carcinoma of the oropharynx (SCCOP) had a longer time to development of distant metastasis (DM) after initial treatment, and had more metastatic sites in more atypical locations compared to HPV-negative patients, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

Predictors of bone metastasis, skeletal events in lung cancer identified

Researchers have identified a range of factors that are associated with the likelihood that a patient with advanced lung cancer will develop bone metastases or skeletal-related events.

20 Feb 2014

Certain fragments of DNA shed by tumors can be used to non-invasively screen for early-stage cancers

Certain fragments of DNA shed by tumors into the bloodstream can potentially be used to non-invasively screen for early-stage cancers, monitor responses to treatment and help explain why some cancers are resistant to therapies, according to results of an international study led by Johns Hopkins Kimmel Cancer Center investigators.

20 Feb 2014

UPV/EHU researchers develop method for diagnosis, prognosis of cutaneous melanoma

UPV/EHU researchers have developed a method for the diagnosis and prognosis of cutaneous melanoma, the type of skin cancer with the highest mortality rate.This method will help not only in the more effective early detection of this cancer, but also in the development of more personalised treatments.

20 Feb 2014

Researchers develop method for diagnosis and prognosis of cutaneous melanoma

19 Feb 2014

New approach for delivering vaccines and for stimulating body's immune system to attack tumors

Many vaccines, including those for influenza, polio, and measles, consist of a killed or disabled version of a virus. However, for certain diseases, this type of vaccine is ineffective, or just too risky.

18 Feb 2014

New research points to potential target for treating triple negative breast cancer

New research from the University of Michigan Comprehensive Cancer Center and Georgia Regents University finds that a protein that fuels an inflammatory pathway does not turn off in breast cancer, resulting in an increase in cancer stem cells. This provides a potential target for treating triple negative breast cancer, the most aggressive form of the disease.

17 Feb 2014

Study affirms new standard for detecting melanoma metastasis to the lymph nodes

Long-term research that was initiated at UCLA's Jonsson Comprehensive Cancer Center on lymphatic mapping and sentinel-node biopsy, techniques for detecting the earliest spread (metastasis) of melanoma, the deadliest form of skin cancer, has confirmed that these techniques significantly prolong patients' disease-free and melanoma-specific survival over the traditional observational "watch and wait" techniques.

14 Feb 2014

New research reveals potential link between alcohol consumption and breast cancer

New research looking at the biological process involved in breast cancer development has strengthened the argument for a potential link between alcohol consumption and the disease.

From The University of Manchester 12 Feb 2014

Metastasis News and Research

Further Reading

Researchers develop new technique to map interactions between proteins at heart of many diseases

Exposure to UV light may exacerbate melanoma cells to creep outside blood vessels

Agendia co-founder to be honored with 2014 European Union Prize for Women Innovators

Verastem presents preliminary data from VS-6063 Phase 1 trial in Japanese patients with solid tumors

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

Blocking myoferlin gene can reduce breast cancer cell migration

Research provides insight into biologic mechanisms that individual cancer cells use to metastasize to brain

Researchers discover that carbohydrates serve as identifiers for cancer cells

Sunburn causes melanoma through direct and indirect processes

NCI recommends renewal for Wistar's Support Grant with award of $14.9M

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Predictors of bone metastasis, skeletal events in lung cancer identified

Certain fragments of DNA shed by tumors can be used to non-invasively screen for early-stage cancers

UPV/EHU researchers develop method for diagnosis, prognosis of cutaneous melanoma

Researchers develop method for diagnosis and prognosis of cutaneous melanoma

New approach for delivering vaccines and for stimulating body's immune system to attack tumors

New research points to potential target for treating triple negative breast cancer

Study affirms new standard for detecting melanoma metastasis to the lymph nodes

New research reveals potential link between alcohol consumption and breast cancer

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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