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UC Davis uses microneedles to deliver gene therapy for retinal diseases

A novel approach to delivering gene therapy for retinal diseases eliminates the need for complex eye surgery and treats more damaged cells than existing methods, a team of UC Davis physicians and veterinary eye specialists has found.

16 Sep 2020

Researchers develop protein-based biosensor for multiplex imaging of neurotransmitter

In 2018, Lin Tian and her team at UC Davis Health developed dLight1, a single fluorescent protein-based biosensor. This family of highly specific sensors detects dopamine, a hormone released by neurons to send signals to other nerve cells.

16 Sep 2020

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

In a recently published study, researchers from the Turku Bioscience Centre at the University of Turku and Åbo Akademi University in Finland monitored the production of new proteins as they were produced by the cells' protein building machinery, the ribosome.

15 Sep 2020

Scientists unlock crucial molecular details regarding tau's activity

Frontotemporal lobar degeneration (FTLD) is a type of dementia that appears earlier in life than Alzheimer's disease (AD).

15 Sep 2020

Facing COVID-19 patients on ventilators down may cause nerve damage

Some people are more likely to experience severe coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These include the elderly, people who are obese and have underlying medical conditions, such as diabetes, obesity, heart disease, lung illness, and kidney disease, among others.

14 Sep 2020

UMSOM researchers determine role of protein in development of hearing hair cells

Researchers at the University of Maryland School of Medicine have conducted a study that has determined the role that a critical protein plays in the development of hair cells.

12 Sep 2020

Severely ill COVID-19 patients on ventilators can experience permanent nerve damage

Severely ill COVID-19 patients on ventilators are placed in a prone (face down) position because it's easier for them to breathe and reduces mortality.

12 Sep 2020

Scientists elucidate cause for Parkinson's disease and identify potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

12 Sep 2020

Brief massage can significantly boost mental and physical relaxation

Allowing yourself a few minutes of downtime significantly boosts mental and physical relaxation. Research by psychologists at the University of Konstanz observed higher levels of psychological and physiological relaxation in people after only ten minutes of receiving a massage.

11 Sep 2020

Alcohol-induced vitamin B1 deficiency can be a key factor in cognitive decline

A common consequence of chronically high alcohol consumption is a decline in cognitive function, which can even progress to full-blown dementia. However, we do not yet fully understand how alcohol damages the brain.

9 Sep 2020

Exploring the possibility that mindfulness with paced breathing reduces blood pressure

According to the American Stroke Association and the American Heart Association, more than 100 million Americans have high blood pressure.

9 Sep 2020

Study shows how inhibitory learning enables memories to be stable over time

In years to come, our personal memories of the COVID-19 pandemic are likely to be etched in our minds with precision and clarity, distinct from other memories of 2020.

9 Sep 2020

Research finds different patterns of blood use in the brains of older women with Type 2 diabetes

A University of Houston researcher is reporting that the brains of older women with Type 2 diabetes do not use as much oxygenated blood as those who don't have the disease.

8 Sep 2020

New medical instruments with smart sensors can improve surgery, therapy for cardiac diseases

Researchers developed a new class of medical instruments equipped with an advanced soft electronics system that could dramatically improve the diagnoses and treatments of a number of cardiac diseases and conditions.

7 Sep 2020

New insights into how the brain can induce diabetes remission in rodents

In rodents with type 2 diabetes, a single surgical injection of a protein called fibroblast growth factor 1 can restore blood sugar levels to normal for weeks or months. Yet how this growth factor acts in the brain to generate this lasting benefit has been poorly understood.

7 Sep 2020

Common class of drugs may be associated with increased risk of cognitive decline

A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer's disease.

5 Sep 2020

IU researcher receives NCI grant to study side effects of cancer treatment

A researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center has been awarded a five-year, $5.7 million National Cancer Institute grant to evaluate long-term health outcomes for cancer patients who receive platinum-based chemotherapies.

5 Sep 2020

Fly brain structure governed by lineage-dependent repulsion mechanism between neurons

The brain's structure has columnar features, which are hypothesized to arise from nerve cells (neurons) stemming from the same parent cell, initially forming radial units. How exactly this process unfolds at the molecular level remains unexplained, however.

5 Sep 2020

AAV gene therapy often leads to dorsal root ganglion pathology, show studies

A meta-analysis of non-human primate (NHP) studies showed that adeno-associated virus (AAV) gene therapy often caused dorsal root ganglion (DRG) pathology.

3 Sep 2020

Experimental drug for ALS shows promising results in clinical trial

An experimental medication slows the progression of the neurodegenerative disease called Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to recently released results from a clinical trial run by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital and Amylyx Pharmaceuticals, Inc., the company that manufactures the medication.

2 Sep 2020

Nerve News and Research

UC Davis uses microneedles to deliver gene therapy for retinal diseases

Researchers develop protein-based biosensor for multiplex imaging of neurotransmitter

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

Scientists unlock crucial molecular details regarding tau's activity

Facing COVID-19 patients on ventilators down may cause nerve damage

UMSOM researchers determine role of protein in development of hearing hair cells

Severely ill COVID-19 patients on ventilators can experience permanent nerve damage

Scientists elucidate cause for Parkinson's disease and identify potential treatments

Brief massage can significantly boost mental and physical relaxation

Alcohol-induced vitamin B1 deficiency can be a key factor in cognitive decline

Exploring the possibility that mindfulness with paced breathing reduces blood pressure

Study shows how inhibitory learning enables memories to be stable over time

Research finds different patterns of blood use in the brains of older women with Type 2 diabetes

New medical instruments with smart sensors can improve surgery, therapy for cardiac diseases

New insights into how the brain can induce diabetes remission in rodents

Common class of drugs may be associated with increased risk of cognitive decline

IU researcher receives NCI grant to study side effects of cancer treatment

Fly brain structure governed by lineage-dependent repulsion mechanism between neurons

AAV gene therapy often leads to dorsal root ganglion pathology, show studies

Experimental drug for ALS shows promising results in clinical trial

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