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Delayed healing linked to weaker electrical currents in diabetic wounds

People with diabetes often suffer from wounds that are slow to heal and can lead to ulcers, gangrene and amputation. New research from an international group led by Min Zhao, professor of ophthalmology and of dermatology at the University of California, Davis, shows that, in animal models of diabetes, slow healing is associated with weaker electrical currents in wounds.

17 Jun 2016

Worsening renal function linked to increased cardiovascular risk in AF

Patients with atrial fibrillation and declining renal function are at increased risk of subsequent stroke or systemic embolism, major bleeding and death, US researchers report.

17 Jun 2016

Mother's obesity can impair health of future generations

New research suggests that mothers who eat high-fat, high-sugar diets can predispose multiple generations to metabolic problems, even if their offspring consume healthy diets.

17 Jun 2016

Epilepsy in immediate family member may increase person’s chances of being diagnosed with autism

Having a first-degree relative with epilepsy may increase a person's risk of being diagnosed with autism, according to a study published in the June 15, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

17 Jun 2016

Cerebral microbleeds linked to increased risk of physical, cognitive disability in MS patients

Leaky blood vessels in the brain called cerebral microbleeds are associated with an increased risk of physical and cognitive disability in patients with multiple sclerosis (MS), according to a new study by researchers in the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo.

17 Jun 2016

S1P1R variation may cause differential patient responses to fingolimod treatment

Multiple sclerosis (MS) is an autoimmune disorder that results in demyelination of neurons. The FDA-approved drug fingolimod (Gilenya, FTY-720) modulates signaling by the bioactive lipid sphingosine-1-phosphate (S1P), which is linked to MS pathogenesis.

16 Jun 2016

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

"Loss is nothing else but change and change is nature's delight" says the quote by the philosopher and emperor Marcus Aurelius, which opens the scientific article that analyses the gene loss phenomenon and its impact on the evolution of living beings.

16 Jun 2016

Brain's reward system in obese people operates differently in response to food and dopamine

As young people reach adulthood, their preferences for sweet foods typically decline. But for people with obesity, new research suggests that the drop-off may not be as steep and that the brain's reward system operates differently in obese people than in thinner people, which may play a role in this phenomenon.

16 Jun 2016

Study finds high prevalence of suicide attempts among arthritis patients

One in every 26 men with arthritis have attempted suicide compared to one in 50 men without arthritis. Women with arthritis also had a higher prevalence of lifetime suicide attempts than women without arthritis (5.3% vs 3.2%), according to a recent study from the University of Toronto.

16 Jun 2016

CD38 enzyme linked to age-related metabolic decline

Researchers at Mayo Clinic have identified the enzyme, called CD38, that is responsible for the decrease in nicotinamide adenine dinucleotide (NAD) during aging, a process that is associated with age-related metabolic decline.

15 Jun 2016

New UCLA study reveals strategy to fight against pesticide-associated Parkinson’s disease

Exposure to a group of common pesticides, called dithiocarbamates, has long been associated with an increased risk of Parkinson's disease, although the mechanism by which the compounds exert their toxicity on the brain has not been completely understood.

15 Jun 2016

Prospective biobank studies with genetic data can help improve drug development, reduce costs

With drug development costs topping $1.2bn (£850 million) to get a single treatment to the point it can be sold and used in the clinic, could genetic analysis save hundreds of millions of dollars?

15 Jun 2016

Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

Researchers at Mayo Clinic have developed an accurate way to measure a circulating factor, called GDF11, to better understand its potential impact on the aging process.

15 Jun 2016

Female migraine patients have increased cardiovascular disease risk

Women who suffer from migraine headaches have a slightly increased risk of developing cardiovascular disease in later life. A team of researchers led by Prof. Tobias Kurth, Head of the Institute of Public Health at Charité - Universitätsmedizin Berlin, has now been able to establish the following: female migraine patients have a higher risk of stroke or heart attacks than women without migraine.

15 Jun 2016

Child adversities linked to high rates of adult insomnia

According to a new study, child adversities, which are known to play an important role in mental and physical health, are also associated with poor sleep.

15 Jun 2016

How can we defeat drug resistance? An interview with Dr Grania Brigden

The O’Neill report is a wide ranging report recognising anti-microbial resistance (AMR) as a global problem with major public health and economic significance.

15 Jun 2016

Researchers reveal how cancer cells use energy to move and divide so quickly

Cancer cells and normal cells both divide and move, but with cancer cells it's like they're on steroids: everything is bigger, faster, more.

15 Jun 2016

CHLA study provides novel insights into the brain mechanisms linked to Prader-Willi syndrome

A study published in the journal Human Molecular Genetics by researchers at Children's Hospital Los Angeles provides novel insights into the brain mechanisms underlying the insatiable hunger and subsequent obesity in patients with Prader-Willi syndrome.

15 Jun 2016

Poor physical fitness, passive hobbies may increase pain conditions in children

Poor physical fitness and sedentary behaviour are linked to increased pain conditions in children as young as 6-8 years old, according to the Physical Activity and Nutrition in Children Study ongoing at the University of Eastern Finland. The findings were published in the Journal of Pain.

14 Jun 2016

Physical activity can counteract genetic risk linked to bone fragility in childhood

Exercise, particularly high-impact activity, builds stronger bones in children, even for those who carry genetic variants that predispose them to bone weakness, according to new research.

14 Jun 2016

X linked News and Research

Delayed healing linked to weaker electrical currents in diabetic wounds

Worsening renal function linked to increased cardiovascular risk in AF

Mother's obesity can impair health of future generations

Epilepsy in immediate family member may increase person’s chances of being diagnosed with autism

Cerebral microbleeds linked to increased risk of physical, cognitive disability in MS patients

S1P1R variation may cause differential patient responses to fingolimod treatment

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

Brain's reward system in obese people operates differently in response to food and dopamine

Study finds high prevalence of suicide attempts among arthritis patients

CD38 enzyme linked to age-related metabolic decline

New UCLA study reveals strategy to fight against pesticide-associated Parkinson’s disease

Prospective biobank studies with genetic data can help improve drug development, reduce costs

Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

Female migraine patients have increased cardiovascular disease risk

Child adversities linked to high rates of adult insomnia

How can we defeat drug resistance? An interview with Dr Grania Brigden

Researchers reveal how cancer cells use energy to move and divide so quickly

CHLA study provides novel insights into the brain mechanisms linked to Prader-Willi syndrome

Poor physical fitness, passive hobbies may increase pain conditions in children

Physical activity can counteract genetic risk linked to bone fragility in childhood

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