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Cinqair (reslizumab) approved for treatment of severe asthma

The U.S. Food and Drug Administration today approved Cinqair (reslizumab) for use with other asthma medicines for the maintenance treatment of severe asthma in patients aged 18 years and older. Cinqair is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

23 Mar 2016

Research findings offer new way to differentiate, treat patients with lung cancer

Research in Manchester has identified mutations in lung cancer that is key to tumour growth, offering a new way to differentiate and treat some patients with the disease.

23 Mar 2016

Scientists provide overview of most promising compounds to combat prostate cancer

Scientists from MIPT (Moscow Institute of Physics and Technology), MSU (Moscow State University), and National University of Science and Technology “MISIS” provided an overview of the most promising compounds which can be used as medications for prostate cancer.

23 Mar 2016

Changes in substance use policies can significantly impact life expectancy

While average life expectancy has been rising steadily in most countries over the past century, new research led by the Centre for Addiction and Mental Health shows that life expectancy declined significantly and rapidly in three countries where policy changes increased access to prescription opioids, alcohol or illicit drugs.

23 Mar 2016

Addition of just two DNA bases to LdAQP1 gene helps Black Fever parasite to overcome antimonial drugs

Wellcome Trust Sanger Institute scientists show how the parasite responsible for the neglected tropical disease Black Fever (visceral leishmaniasis) can become resistant to drug treatment. Studying the whole genomes of more than 200 samples of Leishmania donovani revealed that the addition of just two bases of DNA to a gene known as LdAQP1 stops the parasite from absorbing antimonial drugs.

23 Mar 2016

Study provides better picture of molecular basis for antibiotic resistance

Scientists from the University of Leeds have solved a 25-year-old question about how a family of proteins allow bacteria to resist the effects of certain antibiotics.

23 Mar 2016

Female childhood cancer survivors have a good chance of conceiving

A new study examines fertility issues in male and female childhood cancer survivors who had received chemotherapy. The study found that while most female survivors still have a good chance of conceiving, male survivors are significantly less likely to father children.

23 Mar 2016

Targeted therapies suppress T cell activity that could actually help fight tumors

In many cases, targeted therapies for cancer are preferred as treatments over chemotherapy and surgery because they attack and kill cancer cells with specific tumor-promoting mutations while sparing healthy, normal cells that do not express these mutations.

23 Mar 2016

DAA medication could lead to revolution in hepatitis C treatment

The cost of treating hepatitis C virus (HCV) could be cut up to 50 percent if mathematical models are used to predict when patients can safely stop taking direct-acting antiviral (DAA) medication, according to a new study by researchers at Loyola University Health System and Loyola University Chicago

23 Mar 2016

MU researchers use MRI to study effects of Phenylketonuria

All children are screened for a host of conditions at birth, such as Phenylketonuria (PKU), a genetic disorder that is passed by mutated genes from both parents to their offspring. PKU is rare, only affecting one in every 10,000 children in the U.S.; therefore, it is seldom studied.

23 Mar 2016

Researchers explore new pathways to treat Alzheimer’s

Unless new treatments are found, it is predicted that more than 100 million people worldwide will be affected by Alzheimer's disease by 2050. With very few new drugs in the pipeline, researchers are exploring every possible avenue to treat the disease.

23 Mar 2016

Competition between mixed malaria parasite strains could influence drug resistance

Scientists have documented for the first time how competition among different malaria parasite strains in human hosts could influence the spread of drug resistance.

23 Mar 2016

Warning of increased mortality risk for PD patients taking antipsychotics

Researchers have found a more than twofold increase in the risk of death among patients with Parkinson's disease who take antipsychotics, particularly typical antipsychotics.

23 Mar 2016

Immunoproteasome inhibits repair function of alveolar macrophages

Scientists of Helmholtz Zentrum München, a partner in the German Center for Lung Research, have observed that the immunoproteasome inhibits the repair function of alveolar macrophages.

22 Mar 2016

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

Understanding the origins of emerging diseases - as well as more established disease agents -- is critical to gauge future human infection risks and find new treatment and prevention approaches. This holds true for malaria, which kills more than 500,000 people a year. Symptoms, including severe anemia, pregnancy-associated malaria, and cerebral malaria, have been linked to the parasite's ability to cause infected red blood cells to bind to the inner lining of blood vessels.

22 Mar 2016

Moderate drinking not linked to longer life, study shows

Many people believe a glass of wine with dinner will help them live longer and healthier--but the scientific evidence is shaky at best, according to a new research analysis.

22 Mar 2016

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Vaginal transmission accounts for the majority of new HIV infections worldwide. Forms of pre-exposure prophylaxis (PrEP) such as vaginal gels and vaginal rings designed to prevent HIV transmission have encountered poor efficacy in human trials due to problems with adherence.

22 Mar 2016

Drugs News and Research

Cinqair (reslizumab) approved for treatment of severe asthma

Research findings offer new way to differentiate, treat patients with lung cancer

Scientists provide overview of most promising compounds to combat prostate cancer

Changes in substance use policies can significantly impact life expectancy

Addition of just two DNA bases to LdAQP1 gene helps Black Fever parasite to overcome antimonial drugs

Study provides better picture of molecular basis for antibiotic resistance

Female childhood cancer survivors have a good chance of conceiving

Targeted therapies suppress T cell activity that could actually help fight tumors

DAA medication could lead to revolution in hepatitis C treatment

MU researchers use MRI to study effects of Phenylketonuria

Researchers explore new pathways to treat Alzheimer’s

Competition between mixed malaria parasite strains could influence drug resistance

Warning of increased mortality risk for PD patients taking antipsychotics

Immunoproteasome inhibits repair function of alveolar macrophages

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

Moderate drinking not linked to longer life, study shows

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Tiny gel slivers open way to personalised cancer treatment targeting particular tumour

World TB Day 2016: WHO calls to Unite to End TB

Scientists look for new antibiotic drugs in unexpected places

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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