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Healthy aging brings unexpected benefits to pancreatic beta cell function, insulin production

New research shows that a cellular program that causes aging can also bring unexpected benefits in the function of pancreatic beta cells and the production of insulin in mice and humans.

8 Mar 2016

Merck introduces new products for separation and analysis at Pittcon 2016

Merck, a leading science and technology company is launching a range of new products for separation and analysis at the Pittcon Conference and Expo 2016 in Atlanta, Georgia, March 6 - 10, the world's largest conference for laboratory science.

8 Mar 2016

Rutgers' new drug candidate may help fight malaria

Malaria killed about 440,000 people - mostly young children - last year, but a new drug candidate discovered at Rutgers may help fight the long-dreaded disease.

8 Mar 2016

Bonn scientists identify immune factor partially responsible for chronic viral infection

Many viral diseases tend to become chronic - including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently.

8 Mar 2016

Cause of amyloid beta pathology may be more versatile than previously known

Accumulation of the substance amyloid beta in the brain impairs the memory and cognitive ability in people with Alzheimer's. New findings from Lund University in Sweden show that the cause of amyloid beta pathology might be more versatile than previously known. Researchers believe that these new findings may be of significance to the development of new medications.

8 Mar 2016

Researchers discover how E. coli bacteria adhere to urinary tract

Almost every second woman suffers from a bladder infection at some point in her life. Also men are affected by cystitis, though less frequently. In eighty percent of the cases, it is caused by the intestinal bacterium E. coli.

8 Mar 2016

Research findings offer new way to look at cancer cell metabolism

Cancer cells are notorious for their ability to divide uncontrollably and generate hordes of new tumor cells. Most of the fuel consumed by these rapidly proliferating cells is glucose, a type of sugar.

8 Mar 2016

VTE patients tend to die earlier from bladder cancer

In a study of 3879 patients who underwent radical cystectomy to treat bladder cancer, 3.6% were diagnosed with a venous thromboembolism (VTE)—which occurs when a blood clot forms in a vein, potentially breaking loose and traveling to the lung—within 1 month of their surgical admission date.

8 Mar 2016

Xencor begins XmAb5871 Phase 2 trials in patients with IgG4-RD and Systemic Lupus Erythematosus

Xencor, Inc., a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune diseases, asthma and allergic diseases and cancer, today announced dosing the first patient in a Phase 2 trial of XmAb5871 in patients with IgG4-Related Disease (IgG4-RD).

8 Mar 2016

Blood test may spot first signs of skin cancer relapse

A BLOOD test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing, according to a study published in the journal Cancer Discovery today (Monday).

7 Mar 2016

Systemic sclerosis: an interview with Dr Kristin Highland

Systemic sclerosis, also known as scleroderma, is a rare disease characterized by the thickening and scarring of connective tissue of multiple organs in the body

7 Mar 2016

Sheffield Hallam scientists developing technology to identify risk of caesarean wound infections

Women who have a high body mass index (BMI) are most at risk of developing an infection after a caesarean section, which presents problems for new mothers. But, scientists at Sheffield Hallam's Centre for Health and Social Care Research believe thermal images taken around the area of the wound could detect signs of potential infection just 48 hours after surgery.

7 Mar 2016

Woman's Condom prequalified by WHO/UNFPA

The Woman's Condom, a new female condom designed to be easy to use and more acceptable to women and their partners, has been prequalified by the World Health Organization/United Nations Population Fund. The approval marks a critical step forward in expanding options for female-initiated dual protection from pregnancy and sexually transmitted infections (STIs), including HIV.

7 Mar 2016

FDA allows marketing of one-time use contact lens to help measure patient's intraocular pressure

The U.S. Food and Drug Administration today allowed marketing of a one-time use contact lens that may help practitioners identify the best time of day to measure a patient's intraocular pressure (IOP). Elevated IOP is often associated with the optic nerve damage that is characteristic of glaucoma.

7 Mar 2016

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Scientists from the Cancer Therapy & Research Center in San Antonio today (March 4) published work that provides deeper insight into how the Angelina Jolie gene, BRCA1, functions in normal breast tissue and how its loss results in breast cancer.

7 Mar 2016

First atomic-scale view of interaction between HIV capsid and host protein cyclophilin A

A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is key to HIV infection, researchers say.

7 Mar 2016

Leukemia researchers uncover protein that allows blood cancers to develop

Walter and Eliza Hall Institute researchers have uncovered a protein that is key to the development of blood cancers caused by a common genetic error.

7 Mar 2016

Researchers identify how Zika virus may cause microcephaly in fetuses

Working with lab-grown human stem cells, a team of researchers suspect they have discovered how the Zika virus probably causes microcephaly in fetuses. The virus selectively infects cells that form the brain's cortex, or outer layer, making them more likely to die and less likely to divide normally and make new brain cells.

7 Mar 2016

FSU researchers make major breakthrough in Zika virus research

Florida State University researchers have made a major breakthrough in the quest to learn whether the Zika virus is linked to birth defects with the discovery that the virus is directly targeting brain development cells and stunting their growth.

7 Mar 2016

Idelvion approved for use in children and adults with Hemophilia B

The U.S. Food and Drug Administration today approved Idelvion, Coagulation Factor IX (Recombinant), Albumin Fusion Protein, for use in children and adults with Hemophilia B. Idelvion is the first coagulation factor-albumin fusion protein product to be approved, and the second Factor IX fusion protein product approved in the U.S. that is modified to last longer in the blood.

7 Mar 2016