Genes News and Research

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Researchers identify novel genetic mutations linked to hereditary diffuse gastric cancer

Researchers have identified novel genetic mutations that are linked to hereditary diffuse gastric cancer, with these mutations being due to both independent mutational events and common ancestry, according to a study in the June 6 issue of JAMA.

5 Jun 2007

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in mice

Rats with erectile dysfunction, or ED, that were injected with a gene therapy vector containing either of two nerve growth factors were able to regain normal function after four weeks, according to a study conducted by University of Pittsburgh School of Medicine researchers.

5 Jun 2007

Physiological differences between men and women impact colorectal cancer progression

Physiological differences between men and women may contribute to differential tumor development and progression in colon cancer patients, a study led by researchers at the University of Southern California (USC) suggests.

5 Jun 2007

Men who smoke risk genetic damage to their sperm which is passed on to their children

According to Canadian researchers children could inherit genetic damage from a father who smokes.

3 Jun 2007

Real-time, direct MRI monitoring of vector distribution within the brain

A team of scientists, led by Dr. Krystof Bankiewicz, University of California-San Francisco, presented this significant advance, which allows, for the first time, to adjust parameters of vector infusion while delivering gene therapy, giving surgeon full control over gene transfer technology.

3 Jun 2007

Study tests oral insulin to prevent type 1 diabetes

University of Florida researchers have begun a clinical study of oral insulin to prevent or delay type 1 diabetes in people at risk for the disease.

3 Jun 2007

Novel technologies show promise for future of gene transfer

Several new technologies that could significantly impact the future of gene transfer applications were presented at a conference at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

New platform for regulating the expression of therapeutic genes

A new platform for regulating the expression of therapeutic genes, which will have major implications for gene and cell therapy, was presented at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

New discoveries on genes implicated in Fanconi anaemia

An international research consortium, which included the participation of the Mutagnesi Group from the UAB, has made outstanding progress in the study of Fanconi anaemia.

3 Jun 2007

New protocols to understand embryos, clones, stem cells

Cloning, X-chromosome inactivation, stem cells, and embryogenesis are hot areas of research at the moment, and protocols featured in this month's release of Cold Spring Harbor Protocols will aid these studies.

3 Jun 2007

Smoking can cause changes in the DNA sequence of sperm cells

The science has long been clear that smoking causes cancer, but new research shows that children could inherit genetic damage from a father who smokes.

3 Jun 2007

Insights into a key strategy cancer cells use to survive and thrive

The discovery of how some abnormal cells can avoid a biochemical program of self-destruction by increasing their energy level and repairing the damage, is giving investigators at St. Jude Children's Research Hospital insights into a key strategy cancer cells use to survive and thrive.

3 Jun 2007

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease typically characterized by the slow but progressive onset of shortness of breath or cough.

1 Jun 2007

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

A new study conducted by researchers from the University of Verona and the Institute G. Gaslini in Genova, Italy, confirms the pivotal role played by Cytomegalovirus infection in the pathogenesis of atherosclerosis.

1 Jun 2007

Virus widely used in gene therapy research yields important clues to genomic instability

Genomic instability, the rearrangement of chromosomes or an abnormal number of chromosomes, is a hallmark of many human cancers.

1 Jun 2007

More complete understanding of lactic acid production in muscle

In a paper published in The Journal of Physiology, Frank de Paoli and colleagues, working at the University of Aarhus in Denmark, add to the growing literature leading to a more complete understanding of the physiological role of lactic acid production in muscle.

1 Jun 2007

Discovery of inherited gene mutation for leukemia

Researchers have discovered the first inherited gene mutation that increases a person's risk for chronic lymphocytic leukemia (CLL), one of the most common forms of the disease.

1 Jun 2007

Common cancer gene p53 sends death order to tiny killer

Scientists at Johns Hopkins have discovered one way the p53 gene does what it's known for stopping the colon cancer cells.

1 Jun 2007

Complete sequencing of DNA pioneer James D. Watson

454 Life Sciences Corporation, in collaboration with scientists at the Human Genome Sequencing Center, Baylor College of Medicine, announced in Houston, Texas, the completion of a project to sequence the genome of James D. Watson, Ph.D., co-discoverer of the double-helix structure of DNA.

1 Jun 2007

Herds of cows producing skimmed milk could soon be roaming our pastures

Scientists in New Zealand have discovered that some cows have genes that give them a natural ability to produce skimmed milk and plan to use this information to breed herds of milkers producing only skimmed milk.

30 May 2007