Infectious Diseases News and Research

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Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

One injection of a candidate monoclonal antibody (mAb) known as L9LS was found to be safe and highly protective in U.S. adults exposed to the malaria parasite, according to results from a National Institutes of Health Phase 1 clinical trial published in The New England Journal of Medicine.

4 Aug 2022

New easy-to-use test could rapidly diagnose heart attacks and cancers

Imperial researchers have built a new easy-to-use test that could diagnose non-infectious diseases like heart attacks and cancers more quickly.

4 Aug 2022

Higher suPAR levels linked with increased risk of blood clot formation

Blood clots are thought to occur in as many as a third of patients hospitalized with COVID-19. In many cases these clots can be deadly, such as pulmonary embolisms - blood clots that travel to the lungs. In fact, in nearly one third of patients with COVID-19, these clots led to death.

4 Aug 2022

A California man’s ‘painful and terrifying’ road to a monkeypox diagnosis

Two days after Kevin Kwong flew home to California from New York, his hands itched so badly, the pain jolted him from sleep. He thought the problem was eczema.

4 Aug 2022

Case series of first 3 monkeypox patients in Massachusetts treated with tecoviromat

A team of US-based scientists has described the therapeutic efficacy of a pan-Orthopoxvirus inhibitor, tecovirimat, in patients with monkeypox infection

3 Aug 2022

Are cattle at risk of SARS-CoV-2 infection?

Researchers evaluated antibodies targeting SARS-CoV-2 in cattle from farms in Germany.

3 Aug 2022

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.

3 Aug 2022

Drugs with antiviral activity against monkeypox virus

In a recent study posted as an accepted manuscript in the journal Clinical Infectious Diseases, researchers from the University of Oklahoma described three drugs with antiviral activity against the monkeypox virus (MPXV).

2 Aug 2022

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Human breastmilk has long been considered "liquid gold" among clinicians treating premature infants in a newborn intensive care unit.

2 Aug 2022

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

Pediatric adjuvant formulation offers protection against RSV in newborns

Respiratory syncytial virus (RSV) is the leading global cause of death in children under age 5 and lacks an effective vaccine. In a study from the Precision Vaccines Program at Boston Children's Hospital, a new vaccine formulation protected newborn mice against infection and evoked strong responses in immune cells from human newborns in the laboratory. Results were reported August 2 in Nature Communications.

2 Aug 2022

Study aims to assess the accuracy of influenza rapid diagnostic tests

JMIR Publications recently published "Diagnostic Accuracy of an At-Home, Rapid Self-test for Influenza: Prospective Comparative Accuracy Study" in JMIR Public Health and Surveillance which reported that rapid diagnostic tests (RDTs) for influenza used by individuals at home could potentially expand access to testing and reduce the impact of influenza on health systems.

2 Aug 2022

Long-term symptoms 23 months after SARS-CoV-2 infection

Scientists analyzed COVID-19 symptoms lasting 23 months after the infection.

2 Aug 2022

What are the hidden sources of SARS-CoV-2 evolution?

A recent article published in Transplant Infectious Disease examined case reports on SARS-CoV-2 evolution in immunosuppressed cohorts.

2 Aug 2022

mRNA vaccines induce faster antibody response against infectious diseases

A new study describes that mRNA vaccines induce antigen-specific antibody response within a very short period of time after immunization.

2 Aug 2022

Symptoms of monkeypox differ from previous outbreaks

A new study describes the clinical characteristics of monkeypox infections during the current outbreak.

1 Aug 2022

Nasal epithelium of children inhibits infection and replication of ancestral SARS-CoV-2

SARS-CoV-2 causes a broad range of clinical symptoms, including potentially fatal acute respiratory distress syndrome (ARDS).

1 Aug 2022

Study: SARS-CoV-2 variants of concern and biological sex of patients affect molnupiravir efficacy

SARS-CoV-2 variants of concern and the biological sex of patients affect the efficacy of molnupiravir, the first orally available drug approved for outpatient use against COVID-19, according to a new study led by researchers in the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University.

1 Aug 2022

NIH updates its strategic plan for hepatitis B research

The National Institutes of Health has updated its Strategic Plan for NIH Research to Cure Hepatitis B, a roadmap for ending the hepatitis B epidemic, focused on developing a cure as well as improved strategies for vaccination, screening and follow-up care.

1 Aug 2022

Improving dialogue between healthcare professionals and patients in bladder cancer

In this interview, Dr. Ignacio Duran and Alex Filicevas focus on improving dialogue between healthcare professionals and patients, outlining ways in which we can encourage open discussion to improve the overall patient experience.

From Janssen Pharmaceuticals 1 Aug 2022