Personalized Medicine News and Research

RSS

Gene mutations tied to immune comeback during therapy for HIV-1

A new study by U.S. scientists provides compelling evidence that two genes are linchpins in defining the course of immune restoration in HIV-positive individuals undergoing virus-suppressing therapy.

31 Mar 2008

University of Kentucky physician revolutionizes gene research

A dramatic new study published in the most recent issue of Nature questions some of the mechanisms underlying a new class of drugs based on Nobel Prize-winning work designed to fight diseases ranging from macular degeneration to diabetes.

28 Mar 2008

Wistar Institute shares cell lines

Cell lines developed by scientists at The Wistar Institute in Philadelphia have recently been made available to researchers around the globe through the catalog collection at the Coriell Institute for Medical Research of Camden, N.J.

26 Mar 2008

Deadly genetic disease prevented before birth in zebrafish with genetic patch

By injecting a customized "genetic patch" into early stage fish embryos, researchers at Washington University School of Medicine in St. Louis were able to correct a genetic mutation so the embryos developed normally.

24 Mar 2008

Cholesterol-associated gene variants can predict cardiovascular events

A study appearing in this week's New England Journal of Medicine confirms that a combination of gene variants previously associated with cholesterol levels does reflect patients' cholesterol levels and can signify increased risk of heart attack, stroke or sudden cardiac death.

20 Mar 2008

$New way to predict fracturing in statues and bones$

New way to predict fracturing in statues and bones

For statues, stress injuries come from standing in place for hundreds of years.

19 Mar 2008

Notch protein plays a critical role in bone formation

Notch, a protein known to govern the determination of cell differentiation into different kinds of tissues in embryos, plays a critical role in bone formation and strength later in life, said researchers from Baylor College of Medicine in Houston in a report that appears online today in the journal Nature Medicine.

26 Feb 2008

Researchers find protein targets for potential treatment of multiple sclerosis

Multiple sclerosis is not a single condition, but an ebbing and flowing of stages affecting the body ' s central nervous system.

18 Feb 2008

Personalized medicine can cut breast cancer risk

The time has come for breast cancer risk assessment, counseling and genetic testing to move from cancer specialists to the realm of primary care, according to a presentation at the AAAS annual meeting, held this year in Boston.

17 Feb 2008

Discovery opens door to 'personalized' asthma therapy

In the last few years, "personalized medicine" using genetic or other molecular biology-based diagnostic tests to customize treatment for a particular patient has emerged as a powerful new tool for health care.

18 Jan 2008

Proteomic profiling shown more accurate than traditional biomarkers in identifying liver cancer

As the incidence of liver cancer continues to grow - fueled in large part, by rising rates of hepatitis C infections - so too does the need for tests to help diagnose the disease at an earlier stage.

16 Jan 2008

Genetic differences may explain response to multiple sclerosis treatment

By comparing the DNA of patients with multiple sclerosis whose symptoms are reduced by interferon beta therapy to the DNA of those who continue to experience relapses, researchers may have identified important genetic differences between the two, according to an article posted online that will appear in the March 2008 print issue of Archives of Neurology.

16 Jan 2008

Genetic differences may help explain response to multiple sclerosis treatment

15 Jan 2008

6,000 genes help determine body weight

Reporting in the online journal BMC Genetics, researchers from the Monell Center have for the first time attempted to count the number of genes that contribute to obesity and body weight.

15 Jan 2008

Personalized medicine will alter treatment of genetic disorders

One of the nation's pre-eminent genetic researchers, Eric Hoffman, PhD, of Children's Research Institute at Children's National Medical Center, predicts that in relatively short order, medicine's next innovation--individualized molecular therapies--will have the unprecedented ability to treat muscular dystrophies, and other disorders.

28 Dec 2007

New biochip technology could eliminate animal testing in chemicals and cosmetics industries

A new biochip technology could eliminate animal testing in the chemicals and cosmetics industries, and drastically curtail its use in the development of new pharmaceuticals, according to new findings from a team of researchers at Rensselaer Polytechnic Institute, the University of California at Berkeley, and Solidus Biosciences Inc.

18 Dec 2007

New test for targeted therapy in acute myeloid leukemia

Oregon Health & Science University Cancer Institute researcher Jeff Tyner, Ph.D., has created a way to identify proteins that are candidates for targeted therapy in acute myeloid leukemia using an assay that yields results in just four days.

10 Dec 2007

Latest on research on cancer prevention

Perhaps the best way to fight cancer is to prevent it from developing in the first place.

29 Nov 2007

The science of cancer health disparities in racial/ethnic minorities and the medically underserved

The latest biological, clinical and social research behind how cancer affects different racial and ethnic groups will be the focus of the first American Association for Cancer Research conference on the topic, entitled "The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved."

21 Nov 2007

New technique enables the detection of biomolecules' dynamic reactions in a single living cell

By taking advantage of the signature frequency by which organic and inorganic molecules absorb light, the team of researchers, led by Luke Lee, professor of bioengineering and director of UC Berkeley's Biomolecular Nanotechnology Center, can determine in real time whether specific enzymes are activated or particular genes are expressed, all with unprecedented resolution within a single living cell.

19 Nov 2007