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Scientists identify potent inhibitors to combat common obesity gene

Individuals who are genetically predisposed to obesity may soon have a therapeutic solution to combat their condition. A research team led by scientists from the National University of Singapore (NUS) has identified several potent inhibitors that selectively target FTO, the common fat mass and obesity-associated gene.

21 Oct 2014

Finding could help improve treatment of hearing loss caused by noise, normal aging

Scientists have restored the hearing of mice partly deafened by noise, using advanced tools to boost the production of a key protein in their ears.

21 Oct 2014

New study reveals how cancer becomes drug resistant over time

Like a colony of bacteria or species of animals, cancer cells within a tumor must evolve to survive. A dose of chemotherapy may kill hundreds of thousands of cancer cells, for example, but a single cell with a unique mutation can survive and quickly generate a new batch of drug-resistant cells, making cancer hard to combat.

21 Oct 2014

Identifying infections rapidly: an interview with Dr. David J. Ecker

Current methods for diagnosing infectious diseases are based on the 150-year-old culture method, where physicians collect a sample of a patient’s tissue, such as blood, mucus or urine, and transfer it onto media bottle to allow the pathogens to grow.

From Abbott Diagnostics 20 Oct 2014

Van Andel Research Institute commits $7.5M to support epigenetic therapy in cancer treatment

The work of one of the Stand Up To Cancer (SU2C) inaugural Dream Teams, launched in 2009 to focus on epigenetic therapy in cancer treatment, will continue with the commitment of $7.5 million from Van Andel Research Institute (VARI).

20 Oct 2014

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Janssen Research & Development, LLC today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA (ibrutinib) to the U.S. Food and Drug Administration by its strategic partner Pharmacyclics, Inc.

20 Oct 2014

Study on blind cave fish could reveal mechanisms behind eye disease, other human ailments

Blind cave fish may not be the first thing that comes to mind when it comes to understanding human sight, but recent research indicates they may have quite a bit to teach us about the causes of many human ailments, including those that result in loss of sight.

20 Oct 2014

Researchers propose new milestones to augment National Alzheimer's Plan

The U.S. Government has initiated a major effort to prevent and effectively treat Alzheimer's disease by 2025. However, a workgroup of nearly 40 Alzheimer's researchers and scientists says the research milestones in the U.S. Government's National Plan to Address Alzheimer's Disease must be broadened in scope, increased in scale, and adequately funded in order to successfully achieve this goal.

20 Oct 2014

Researchers identify genetic variant in Latina women that protects against breast cancer

An international research collaboration led by UC San Francisco researchers has identified a genetic variant common in Latina women that protects against breast cancer.

20 Oct 2014

Whole exome sequencing can assist in early diagnosis of various disorders

Approximately one-fourth of the 3,386 patients whose DNA was submitted for clinical whole exome testing received a diagnosis related to a known genetic disease, often ending a long search for answers for them and their parents, said researchers from the Baylor College of Medicine departments of molecular and human genetics and pediatrics and the Baylor Human Genome Sequencing Center and the University of Texas Health Science Center at Houston.

20 Oct 2014

Genetic changes in blood cells of older people linked to lymphoma, leukemia

At least 2 percent of people over age 40 and 5 percent of people over 70 have mutations linked to leukemia and lymphoma in their blood cells, according to new research at Washington University School of Medicine in St. Louis.

20 Oct 2014

Children infected with enterovirus more likely to have type 1 diabetes

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that children who have been infected with enterovirus are 48% more likely to have developed type 1 diabetes. The study is by Dr Tsai Chung-Li, China Medical University, Taiwan, and colleagues.

20 Oct 2014

New research shows link between birth season and mood disorders

New research shows that the season you are born has a significant impact on your risk of developing mood disorders. People born at certain times of year may have a greater chance of developing certain types of affective temperaments, which in turn can lead to mood disorders (affective disorders).

20 Oct 2014

State highlights: Calif.'s Prop. 45 fight; new benefits for same sex couples in N.C.; Aetna sheds jobs after Medicaid drop

A selection of health policy stories from California, North Carolina, Delaware, New York, Georgia, Pennsylvania, New Jersey, Florida and Kansas.

17 Oct 2014

Genome Canada awards $6M grant to CAMH and Assurex Health

Assurex Health and Canada's Centre for Addiction and Mental Health (CAMH) today announced they have received a $6 million grant from Genome Canada, an agency of the Canadian government, to study the benefits of genetic testing to guide medication decisions for patients with depression or schizophrenia.

17 Oct 2014

Genetic News and Research

Scientists identify potent inhibitors to combat common obesity gene

Finding could help improve treatment of hearing loss caused by noise, normal aging

New study reveals how cancer becomes drug resistant over time

Identifying infections rapidly: an interview with Dr. David J. Ecker

Van Andel Research Institute commits $7.5M to support epigenetic therapy in cancer treatment

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Study on blind cave fish could reveal mechanisms behind eye disease, other human ailments

Researchers propose new milestones to augment National Alzheimer's Plan

Researchers identify genetic variant in Latina women that protects against breast cancer

Whole exome sequencing can assist in early diagnosis of various disorders

Genetic changes in blood cells of older people linked to lymphoma, leukemia

Children infected with enterovirus more likely to have type 1 diabetes

New research shows link between birth season and mood disorders

State highlights: Calif.'s Prop. 45 fight; new benefits for same sex couples in N.C.; Aetna sheds jobs after Medicaid drop

Genome Canada awards $6M grant to CAMH and Assurex Health

Researchers receive NIH grant to study mechanisms of auditory hypersensitivity in fragile X syndrome

Genetic risk for ADHD contributes to language, attention deficits in general population

IU Bloomington biologists to receive funding from NSF’s Dimensions of Biodiversity Program

Inpatient palliative care can considerably reduce readmissions, hospital costs, shows study

Researchers identify novel method to develop personalized vaccines for ovarian cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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