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FDA requests $5.1 billion budget for FY 2017 to protect and promote public health

The U.S. Food and Drug Administration is requesting a total budget of $5.1 billion to protect and promote the public health as part of the President's fiscal year (FY) 2017 budget – an eight percent increase over the enacted budget for FY 2016.

10 Feb 2016

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research.

9 Feb 2016

Study provides insights into molecular basis of Frank-Starling regulatory mechanism

In a finding that could lead to new drugs to treat heart failure, researchers have uncovered the molecular mechanism that regulates how the heart pumps blood.

9 Feb 2016

New study pinpoints two tiny clusters of neurons responsible for changing normal breaths into sighs

"You must remember this: a kiss is just a kiss, a sigh is just a sigh." Contrary to the words immortalized by the piano singer in "Casablanca," a sigh is far more than a sigh. Heaving an unconscious sigh is a life-sustaining reflex that helps preserve lung function.

9 Feb 2016

Insulin remains expensive and beyond the reach of many diabetics worldwide

More than 90 years after it was first discovered, and despite being listed as an essential medicine by the World Health Organization (WHO) since 2007, the lifesaving diabetes drug, insulin, remains very expensive and beyond the reach of many people with type 1 and 2 diabetes who need it globally, say leading experts writing in The Lancet Diabetes & Endocrinology journal.

9 Feb 2016

Vienna researchers investigate new light therapy treatment for people with migraines

Migraines often involve heightened sensitivity to light. In a project funded by the Austrian Science Fund FWF, a team of researchers from the Medical University of Vienna is investigating new therapies to treat light sensitivity, which greatly disturbs those affected.

9 Feb 2016

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

A research team led by St. Jude Children's Research Hospital scientists has discovered details of how the abnormal breakage and rearrangement of chromosomes in white blood cells triggers a particularly aggressive form of acute lymphoblastic leukemia (ALL). Such leukemias are cancers of white blood cells, in which genetic mutations trigger overproduction of immature cells, called lymphoblasts.

9 Feb 2016

Wayne State inks exclusive license agreement with TRImaran Pharma for novel class of drugs

Wayne State University recently entered into an exclusive license agreement with TRImaran Pharma Inc. for a class of novel drugs developed at Wayne State University that aims to offer hope in the treatment of post-traumatic stress disorders (PTSD), depression, ADHD and other neurological disorders.

9 Feb 2016

Implantable device could help deliver toxic cocktail of drugs directly to pancreatic tumors

A highly lethal cancer sometimes requires large doses of highly toxic drugs. However, a blitzkrieg approach can be unfeasible for some patients due to severe side effects. Now a powerhouse team of researchers at the University of North Carolina at Chapel Hill has revealed that an implantable device can deliver a particularly toxic cocktail of drugs directly to pancreatic tumors to stunt their growth or in some cases, shrink them - all while showing signs that the rest of the body would be spared toxic side effects.

9 Feb 2016

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

An experimental nanoparticle therapy that combines low-density lipoproteins (LDL) and fish oil preferentially kills primary liver cancer cells without harming healthy cells, UT Southwestern Medical Center researchers report.

9 Feb 2016

Benzodiazepine dementia risk refuted

Benzodiazepines, commonly used by older adults to manage sleep, anxiety and depressive disorders, do not increase the risk of dementia or hasten cognitive decline, study findings show.

8 Feb 2016

BetterYou's revolutionary daily oral vitamin spray could boost vitamin D levels in children with epilepsy

A revolutionary daily oral vitamin spray by health pioneers BetterYou can boost vitamin D levels in deficient children, particularly common in those with epilepsy.

From BetterYou Ltd 8 Feb 2016

UIC researchers discover molecular switch that allows salmonella bacteria to fight immune system

Researchers at the University of Illinois at Chicago have discovered a molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm.

7 Feb 2016

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity.

5 Feb 2016

Discovery takes researchers one step closer to preventing C. diff

Exposure to specific antibiotics is linked to the development of certain strains of antibiotic-resistant C. difficile, one of the fastest growing bacteria superbugs, according to a new study published by Stuart Johnson, MD, of Loyola University Health System, Loyola University Chicago Stritch School of Medicine and the Hines VA Medical Hospital.

5 Feb 2016

FDA's PDAC supports use of Brintellix for treating cognitive dysfunction in adults with MDD

Takeda Pharmaceutical Company Limited and H. Lundbeck A/S today announced that the U.S. Food and Drug Administration’s Psychopharmacologic Drugs Advisory Committee voted 8 to 2 that the companies presented substantial evidence to support the effectiveness of Brintellix (vortioxetine) for treating certain aspects of cognitive dysfunction in adults with Major Depressive Disorder (MDD).

5 Feb 2016

World Hepatitis Alliance calls for comprehensive hepatitis strategies to help prevent liver cancer deaths

Rock-icon David Bowie died recently at the age of 69 after a battle with what is being reported as liver cancer. Each year, more than 800,000 people die from liver cancer globally, the second biggest cancer killer. Yet, a high majority of these deaths are completely preventable.

5 Feb 2016

Early use of influenza drug in pregnant women with flu may reduce length of stay in hospital

Pregnant women are at higher risk for serious illness and complications, including death, from influenza. For expectant mothers hospitalized with flu, early treatment with the influenza antiviral drug oseltamivir may shorten their time in the hospital, especially in severe cases, suggests a new study published in The Journal of Infectious Diseases and available online.

5 Feb 2016

Meditation reduces anxiety, pain and fatigue in women undergoing breast cancer biopsies

Meditation eases anxiety, fatigue and pain for women undergoing breast cancer biopsies, according to researchers at the Duke Cancer Institute. They also found that music is effective, but to a lesser extent.

5 Feb 2016

Study: Prior surgical abortion appears to increase risk of later preterm birth

Surgical methods used in a common form of abortion or to clear the womb after a spontaneous miscarriage appears to significantly increase the risk of a later preterm birth, say researchers at Thomas Jefferson University who analyzed 36 studies that enrolled more than 1 million women.

4 Feb 2016

Drugs News and Research

FDA requests $5.1 billion budget for FY 2017 to protect and promote public health

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

Study provides insights into molecular basis of Frank-Starling regulatory mechanism

New study pinpoints two tiny clusters of neurons responsible for changing normal breaths into sighs

Insulin remains expensive and beyond the reach of many diabetics worldwide

Vienna researchers investigate new light therapy treatment for people with migraines

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

Wayne State inks exclusive license agreement with TRImaran Pharma for novel class of drugs

Implantable device could help deliver toxic cocktail of drugs directly to pancreatic tumors

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

Benzodiazepine dementia risk refuted

BetterYou's revolutionary daily oral vitamin spray could boost vitamin D levels in children with epilepsy

UIC researchers discover molecular switch that allows salmonella bacteria to fight immune system

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Discovery takes researchers one step closer to preventing C. diff

FDA's PDAC supports use of Brintellix for treating cognitive dysfunction in adults with MDD

World Hepatitis Alliance calls for comprehensive hepatitis strategies to help prevent liver cancer deaths

Early use of influenza drug in pregnant women with flu may reduce length of stay in hospital

Meditation reduces anxiety, pain and fatigue in women undergoing breast cancer biopsies

Study: Prior surgical abortion appears to increase risk of later preterm birth

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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