Intensive Care News and Research

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Researchers review all clinical and research findings related to COVID-19

Due to the devastating worldwide impact of COVID-19, the illness caused by the SARS-CoV-2 virus, there has been unprecedented efforts by clinicians and researchers from around the world to quickly develop safe and effective treatments and vaccines.

29 May 2020

Relaxation of physical distancing may increase the spread of COVID-19 in Ontario

If physical distancing measures in Ontario are relaxed too much or too quickly, the province could see hospitals overwhelmed with COVID-19 patients as well as exponential growth in deaths, concludes new research involving a University of Guelph infectious disease modeller.

29 May 2020

Rare deadly disease linked to coronavirus infection seen in children

Now, new evidence has shown that children with coronavirus disease (COVID-19) experience a Kawasaki-like illness, called multisystem inflammatory syndrome in children (MIS-C). The complication is akin to toxic shock syndrome, a condition that occurs due to sepsis. Though rare, the condition is life-threatening.

29 May 2020

Brazilian researchers design low-cost mechanical ventilators

A group of researchers at the University of São Paulo's Engineering School (POLI-USP) in Brazil have developed a mechanical ventilator that costs only approximately 7% as much as a conventional ventilator.

28 May 2020

Experts issue new guidance to improve stroke care amid COVID-19

Top stroke experts have issued new guidance to ensure stroke patients receive safe, timely care while preventing the transmission of COVID-19.

28 May 2020

Johns Hopkins team develops new method to maintain sufficient supplies of kidney dialysis fluid

The ongoing COVID-19 pandemic has severely impacted the manufacturing and supply chains for many products.

28 May 2020

Molecular signatures can predict outcome of sepsis patients based on their immune response

Scientists have identified molecular signatures in the immune component of the blood which indicate how patients in intensive care with sepsis, septic shock and systemic inflammatory response syndrome are likely to respond to the conditions.

28 May 2020

Canadian study of COVID-19 patients admitted to ICUs finds lower overall mortality

A Canadian case series of all patients with COVID-19 admitted to six intensive care units (ICUs) in Metro Vancouver found patient outcomes were substantially better than reported in other jurisdictions. The paper is published in CMAJ.

27 May 2020

SARS-CoV-2 RNA in blood tests not associated with infectious virus

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has challenged hospitals and laboratory services worldwide. Diagnostic testing for SARS-CoV-2 initially lagged but is now primarily based on the use of reverse transcriptase-polymerase chain reaction (RT-PCR) to detect viral nucleic RNA in the samples. However, viral RNA has also been reported in several small series of cases, though its significance and frequency remain unclear.

27 May 2020

COVID-19 Rapid Research Fund allows coronavirus research in Ontario and London

Sepsis is a life-threatening condition. It occurs when the body's response to an infection is out of balance, triggering hyperinflammation that can damage multiple organs.

27 May 2020

First independent test of proposed subphenotypes of COVID-19-related ARDS

In a new paper published online in the Annals of the American Thoracic Society, researchers have been unable to produce two theorized subphenotypes of COVID-19 related acute respiratory distress syndrome (ARDS).

27 May 2020

Study highlights the benefits of palliative care for heart failure patients

Palliative care is valuable for heart failure patients, and, for those who are hospitalized, it can significantly lower the risk of repeated hospital admissions and the need for invasive procedures such as mechanical ventilation and defibrillator implantation, according to new research published today in the Journal of the American Heart Association, an open-access journal of the American Heart Association.

27 May 2020

Blood clotting disorders may explain some of the worst symptoms of COVID-19

The hypothesis that blood clotting disorders may explain some of the worst symptoms of COVID-19, including respiratory failure and pulmonary fibrosis, was suggested in mid-April by researchers in Brazil affiliated with the University of São Paulo's Medical School (FM-USP) via an article accepted for publication by the Journal of Thrombosis.

27 May 2020

Meta-analysis of latest second-line treatments for status epilepticus

Status epilepticus (SE) is the most common neurologic emergency, with rates estimated between 1.3 and 81 cases per 100,000 people per year.

27 May 2020

What affects the case fatality rate of COVID-19? Analysis of top 50 affected countries

Ever since the beginning of the international spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease, researchers have been trying to identify the risk factors that increase the chances of infection. Now, a new study published on the preprint server medRxiv in May 2020 discusses various potential factors and reports the observed associations.

27 May 2020

Heparin resistance among COVID-19 patients admitted to ICU

A new study has shown that COVID-19 patients admitted to the Intensive care unit may be resistant to the naturally occurring anticoagulant Heparin. The study titled, “Heparin resistance in COVID‑19 patients in the intensive care unit,” was published in the latest issue of the Journal of Thrombosis and Thrombolysis.

26 May 2020

U.S. COVID-19 patients face long hospital stays and high rates of ICU admission

Hospitalized COVID-19 patients in the U.S. are enduring longer hospital stays and facing higher rates of intensive care unit admission than patients in China, finds a new study led by researchers at the University of California, Berkeley, and Kaiser Permanente.

26 May 2020

COVID-19 appears to attack the placenta in pregnant women

Pregnant women should take extra precautions amid the coronavirus pandemic. A new study shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), attacks the placenta.

26 May 2020

Preterm birth rates during COVID-19 in Denmark

The current COVID-19 outbreak was declared a pandemic in March 2020 by the World Health Organization (WHO). This led to the enforcement of a lockdown on an almost global scale with wide-ranging consequences. Now, a new Danish study published on the preprint server medRxiv* in May 2020 reveals the impact on preterm birth rates.

26 May 2020

Can Chlorpromazine help treat COVID-19?

A new research paper published in the journal L'Encéphale in May 2020 reports on the planned ReCoVery Study, which will examine the possibility of repurposing the antipsychotic drug chlorpromazine for the treatment of COVID-19.

25 May 2020