Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Cellular self-digestion process plays role in development of autoimmune diseases

Autophagy allows cells to degrade and recycle their cellular components. Researchers at UZH have now demonstrated that the autophagy machinery in certain immune cells leads to the immune system attacking the central nervous system.

13 Dec 2017

Time-lapse imaging reveals how antimicrobial treated surfaces kill superbugs in two hours

Experts at the University of Warwick have produced microscopic footage of the potentially deadly E. coli bacteria being wiped out in just two hours on an antimicrobial treated ‘intelligent’ surface.

13 Dec 2017

Caris Life Sciences reveals identification of new mechanism of action to treat NHL

Caris Life Sciences, a leading innovator in molecular science focused on fulfilling the promise of precision medicine, today announced a data presentation, at the 59th American Society of Hematology Annual Meeting & Exposition in Atlanta, demonstrating the identification of a new mechanism of action to treat non-Hodgkin lymphoma (NHL).

13 Dec 2017

Tapeworm drug could provide new hope for patients with Parkinson's disease

Researchers at Cardiff University, in collaboration with the University of Dundee, have identified a drug molecule within a medicine used to treat tapeworm infections which could lead to new treatments for patients with Parkinson's disease.

12 Dec 2017

Retinal diseases could be treated by ophthalmic drops instead of intraocular injections

The Spanish firm Sylentis has developed a compound to treat diseases of the retina, such as age-related macular degeneration and diabetic retinopathy, which will be administered by ophthalmic drops instead of intraocular injections.

12 Dec 2017

New scientific yardstick released to help early detection of Alzheimer's disease

The European Commission's Joint Research Centre released a new scientific yardstick, in the form of a certified reference material, to help early detection of Alzheimer's disease.

12 Dec 2017

Researchers identify promising solution for improving cystic fibrosis treatments

Researchers at the University of Montreal Hospital Research Centre have identified a promising solution to improving treatments offered to patients with cystic fibrosis.

12 Dec 2017

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To this day, no therapy will put a stop to the insidious disintegration of brain cells.

12 Dec 2017

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

Huntington's disease drug clears initial hurdles - raising hopes

Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the cause behind this dreaded disease has been found to be effective, safe and well tolerated in a human clinical trial that was conducted by UCL scientists.

11 Dec 2017

Having older brothers may increase the likelihood of being gay

Scientists have found a distinct pattern that having older brothers raise the chances of the younger sibling being gay. This effect has been termed the “fraternal birth order effect”. They explain the biological reason behind this propensity in their new study that was published this week in the journal PNAS.

11 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Researchers uncover novel strategy to program immune system for fighting cancer

Looking to bolster the body's immune system in the fight against infection and cancer, researchers at the University of California San Diego and their colleagues have identified a promising new strategy to program the immune system to meet the pathogen or malignancy in the tissues where they first pose a threat.

11 Dec 2017

Study provides new insights into mechanism of tumor survival in glioblastoma

A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy.

11 Dec 2017

Researchers discover potential regulator essential for killer T cells to reside in tumors

Researchers report the discovery that a protein called "Runx3" programs killer T cells to establish residence in tumors and infection sites.

11 Dec 2017

Scientists discover specific mechanism of Zika virus-associated microcephaly

Epidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development of the cerebral cortex.

11 Dec 2017

Russian researchers create new approaches to prevention and treatment of diabetes

A team of scientists from the Ural Federal University and the Institute of Immunology and Physiology modeled type 1 diabetes in an experiment to study recovery processes in the pancreas.

11 Dec 2017

New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

Kidney dysfunction raises diabetes risk, study suggests

Diabetes is known to increase a person's risk of kidney disease. Now, a new study from Washington University School of Medicine in St. Louis suggests that the converse also is true: Kidney dysfunction increases the risk of diabetes.

11 Dec 2017

Protein News and Research

Further Reading

Cellular self-digestion process plays role in development of autoimmune diseases

Time-lapse imaging reveals how antimicrobial treated surfaces kill superbugs in two hours

Caris Life Sciences reveals identification of new mechanism of action to treat NHL

Tapeworm drug could provide new hope for patients with Parkinson's disease

Retinal diseases could be treated by ophthalmic drops instead of intraocular injections

New scientific yardstick released to help early detection of Alzheimer's disease

Researchers identify promising solution for improving cystic fibrosis treatments

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Researchers find new role for SHARPIN protein in melanoma growth

Huntington's disease drug clears initial hurdles - raising hopes

Having older brothers may increase the likelihood of being gay

Study: Combination targeted therapy has high response rates in AML patients

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Researchers uncover novel strategy to program immune system for fighting cancer

Study provides new insights into mechanism of tumor survival in glioblastoma

Researchers discover potential regulator essential for killer T cells to reside in tumors

Scientists discover specific mechanism of Zika virus-associated microcephaly

Russian researchers create new approaches to prevention and treatment of diabetes

New, more easily administered therapies offer benefits for bleeding and clotting disorders

Kidney dysfunction raises diabetes risk, study suggests

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