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CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites.

19 Jan 2016

Insulet donates $10,000 each to ADA and JDRF to improve lives of people living with diabetes

Insulet Corporation, the leader in tubeless insulin pump technology with its OmniPod Insulin Management System, today announced that is has donated $10,000 each to the American Diabetes Association and the Juvenile Diabetes Research Foundation.

19 Jan 2016

Researchers suggest ways to make TB drugs more efficacious against mutations

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed three-dimensional structure of the drugs interacting with an essential enzyme in the TB germ, also reveal why some TB drugs are more potent than others and suggest how drug developers can make fluoroquinolones more efficacious against mutations that make the lung disease drug resistant.

19 Jan 2016

Researchers identify protein structure linked to pain and heat perception

Touch a hot stove, and your fingers will recoil in pain because your skin carries tiny temperature sensors that detect heat and send a message to your brain saying, "Ouch! That's hot! Let go!"

19 Jan 2016

Combination of PARP inhibitors and c-MET may benefit breast cancer patients

Findings from a new study reveal that PARP inhibitors, an emerging class of drugs being studied in cancer clinical trials, may be enhanced by combining them with inhibitors targeting an oncogene known as c-MET which is overexpressed in many cancers.

19 Jan 2016

Omnicell's revolutionary medication automation cabinet system saves cost, increases efficiency

An 18-month trial in the trust which opened England’s first hospital dedicated to emergency care, Northumbria Specialist Emergency Care Hospital, has found that significant cost-savings and efficiencies can be made by installing a revolutionary medication automation cabinet system provided by Omnicell Ltd, a leading provider of medication adherence packaging and automated healthcare solutions.

19 Jan 2016

BENEPALI granted marketing authorization in the EU for treatment of chronic inflammatory diseases

The joint venture between Biogen and Samsung BioLogics, Samsung Bioepis, has been granted European Commission (EC) approval for BENEPALI , an etanercept biosimilar referencing Enbrel.

19 Jan 2016

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

We've all seen the headlines. "Man found to be shedding virulent strain of polio"; "Virulent flu strain in Europe hits the economy"; "Most virulent strain of E. coli ever seen contains DNA sequences from plague bacteria."

19 Jan 2016

New method helps generate cardiac cells for heart disease studies, drug discovery

For a team of Vanderbilt investigators trying to generate heart muscle cells from stem cells, a piece of broken equipment turned out to be a good thing.

18 Jan 2016

NSCLC treatments market in Europe expected to cross US$ 3 billion by 2019

According to recently published Pharmaion report, "Europe Non-Small Cell Lung Cancer Treatments Market Opportunities, 2010 - 2020", the non-small cell lung cancer (NSCLC) treatments market in Europe is anticipated to cross US$ 3 billion by 2019.

18 Jan 2016

UM SOM selected to work with BARDA to develop radiologic and nuclear countermeasures

University of Maryland School of Medicine Department of Radiation Oncology Chair and Professor William F. Regine, MD, FACR, FACRO, and UM SOM Dean E. Albert Reece, MD, PhD, MBA, announced today that researchers at the UM SOM have been selected as key contractors by the Biomedical Advanced Research and Development Authority, for its Radiation Nuclear Animal Model Development program.

18 Jan 2016

TSRI researchers develop new technique for modifying complex drug molecules

Chemists at The Scripps Research Institute have developed a versatile new technique for making modifications—especially one type of extremely difficult, but much-sought-after modification—to complex drug molecules.

18 Jan 2016

FDA issues draft guidance to address cybersecurity vulnerabilities in medical devices

The U.S. Food and Drug Administration today issued a draft guidance outlining important steps medical device manufacturers should take to continually address cybersecurity risks to keep patients safe and better protect the public health.

18 Jan 2016

The Mobile App That's Making Prescribing Drugs Easier and Safer

News-Medical speaks to Dr. Volpe about the development of an app that allows physicians to access up-to-date medical information at the touch of a button!

From Physicians' Desk Reference (PDR) 18 Jan 2016

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Pediatric researchers at UT Southwestern Medical Center have identified a key component of the pathogenesis of bronchopulmonary dysplasia (BPD), a devastating and sometimes fatal lung disease that affects premature infants. Their findings clarify what prompts the inflammatory response that results in BPD, which previously had been unclear.

18 Jan 2016

Scientists find new way to re-engineer body’s immune system to target cancer

Scientists have demonstrated a new way of re-engineering the body’s immune system to target cancer, paving the way for a new generation of drugs, unprecedented in safety and effectiveness.

18 Jan 2016

New BSR guidelines on prescribing anti-rheumatic medication during pregnancy, breastfeeding

The new BSR guidelines make a number of specific recommendations for the use of standard and/or biologic disease modifying anti-rheumatic drugs (DMARDs), providing crucial advice for clinicians, obstetricians and midwives.

18 Jan 2016

Researchers identify origins of aggressive childhood lymphoma

The origins of a type of aggressive childhood lymphoma have been found, giving hope that new drugs could be designed to prevent the disease coming back after treatment.

18 Jan 2016

Oral drug rivastigmine could help prevent falls in people with Parkinson’s

Scientists have discovered that a commonly prescribed dementia drug could hold the key to helping prevent debilitating falls for people with Parkinson’s.

18 Jan 2016

Anti-cancer drug uses 50 times less chemo to effectively destroy drug-resistant lung cancer

The cancer drug paclitaxel just got more effective. For the first time, researchers from the University of North Carolina at Chapel Hill have packaged it in containers derived from a patient's own immune system, protecting the drug from being destroyed by the body's own defenses and bringing the entire payload to the tumor.

18 Jan 2016

Drugs News and Research

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

Insulet donates $10,000 each to ADA and JDRF to improve lives of people living with diabetes

Researchers suggest ways to make TB drugs more efficacious against mutations

Researchers identify protein structure linked to pain and heat perception

Combination of PARP inhibitors and c-MET may benefit breast cancer patients

Omnicell's revolutionary medication automation cabinet system saves cost, increases efficiency

BENEPALI granted marketing authorization in the EU for treatment of chronic inflammatory diseases

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

New method helps generate cardiac cells for heart disease studies, drug discovery

NSCLC treatments market in Europe expected to cross US$ 3 billion by 2019

UM SOM selected to work with BARDA to develop radiologic and nuclear countermeasures

TSRI researchers develop new technique for modifying complex drug molecules

FDA issues draft guidance to address cybersecurity vulnerabilities in medical devices

The Mobile App That's Making Prescribing Drugs Easier and Safer

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Scientists find new way to re-engineer body’s immune system to target cancer

New BSR guidelines on prescribing anti-rheumatic medication during pregnancy, breastfeeding

Researchers identify origins of aggressive childhood lymphoma

Oral drug rivastigmine could help prevent falls in people with Parkinson’s

Anti-cancer drug uses 50 times less chemo to effectively destroy drug-resistant lung cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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