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Project aims at establishing central biobank for development of new drugs

Human stem cells allow scientists to assess how patients are likely to respond to new drugs and to examine how illnesses come about.

4 Sep 2014

Researchers uncover intriguing link between heart attacks and protein

A team of researchers at the University of Ottawa Heart Institute, led by Dr. Alexandre Stewart, have uncovered an intriguing link between heart attacks and a protein that is of great interest to drug companies for its impact on cholesterol.

4 Sep 2014

Scientists identify genetic mutations in endometrioid endometrial carcinoma

Parents of twins often tell them apart through subtle differences such as facial expression, moles, voice tone and gait. Similarly, physicians treating women with endometrial cancer must be able to distinguish between different versions of this disease form that, on the surface, appear the same.

4 Sep 2014

Artificial cells to devour undesirables: an interview with Dr. Takanari Inoue

If junk is not removed, pathological conditions can develop. For example, in one condition, the neutrophil count significantly decreases. Neutrophils remove pathogens and people with a reduced neutrophil count are more prone to infection, especially to rare bacteria that wouldn’t cause infection under normal conditions.

3 Sep 2014

Distinct features of COPD–asthma overlap syndrome identified

US researchers have shown that patients with both chronic obstructive pulmonary disease and asthma have more exacerbations, less emphysema and more airway disease than patients with COPD alone.

3 Sep 2014

Measuring levels of sex hormones in patients' blood may identify risk of sudden cardiac arrest

Measuring the levels of sex hormones in patients' blood may identify patients likely to suffer a sudden cardiac arrest, a heart rhythm disorder that is fatal in 95 percent of patients.

3 Sep 2014

Researchers identify different types of tuberculosis using new genetic barcode

Doctors and researchers will be able to easily identify different types of tuberculosis (TB) thanks to a new genetic barcode devised by scientists from the London School of Hygiene & Tropical Medicine.

3 Sep 2014

Around 9.6% of women diagnosed with dry eye disease, treated with artificial tear eye drops

The symptoms of dry eye disease include the sensation of grit in the eye, frequently accompanied by itching, burning and visual disturbance. The causes are poorly understood.

3 Sep 2014

New approach to turn diseased cells into unique manufacturing sites for treating muscular dystrophy

In a new study that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have adapted a chemical approach to turn diseased cells into unique manufacturing sites for molecules that can treat a form of muscular dystrophy.

3 Sep 2014

White pill may help scientists learn why patients with cystic fibrosis have less exercise capacity

A little white pill may help scientists learn why patients with cystic fibrosis have less exercise capacity than their peers, even if their lungs are relatively healthy.

3 Sep 2014

Coffee increases risk of prediabetes in young adults with hypertension

Coffee increases the risk of prediabetes in young adults with hypertension who are slow caffeine metabolisers, according to results from the HARVEST study presented at ESC Congress today by Dr Lucio Mos from Italy. People who drank more than three cups of coffee per day doubled their risk of prediabetes.

2 Sep 2014

Concordia's subsidiary signs collaboration deal with Orphan Canada for PHOTOFRIN

Concordia Healthcare Corp., a diverse healthcare company focused on legacy pharmaceutical products, orphan drugs, and medical devices for the diabetic population, today announced that its subsidiary, Pinnacle Biologics, Inc., a biopharmaceutical research and development company specializing in rare diseases, has signed a collaboration agreement for PHOTOFRIN® with Orphan Canada, a Toronto-based specialty pharmaceutical company that in‐licenses therapies for rare disorders and specialty medicines within Canada.

2 Sep 2014

Cepheid releases Xpert Flu/RSV XC for accurate determination of Flu A, Flu B and RSV infection

Cepheid announced today the release of Xpert® Flu/RSV XC, an on-demand molecular test for rapid, accurate and reliable determination of Flu A, Flu B, and differentiation of RSV infection.

2 Sep 2014

Finding could lead researchers to better understand development of psychiatric disorders

Some people take stress in stride; others are done in by it. New research at Rockefeller University has identified the molecular mechanisms of this so-called stress gap in mice with very similar genetic backgrounds - a finding that could lead researchers to better understand the development of psychiatric disorders such as anxiety and depression.

2 Sep 2014

Flow through pain-sensing molecule helps worms adapt to pain

When you accidentally touch a hot oven, you rapidly pull your hand away. Although scientists know the basic neural circuits involved in sensing and responding to such painful stimuli, they are still sorting out the molecular players.

2 Sep 2014

New genetic barcode helps identify different types of tuberculosis

2 Sep 2014

Internal production of hydrogen peroxide can lead cells to exit cell cycle and become senescent

What happens inside cells when they detect the activation of a cancer-inducing gene? Sometimes, cells are able to signal internally to stop the cell cycle. Such cells are able to enter, at least for a time, a protective non-growth state.

30 Aug 2014

Special issue looks at how researchers use bioinformatics to understand plant form

As technology advances, science has become increasingly about data-how to gather it, organize it, and analyze it.

30 Aug 2014

Dartmouth researchers evaluate role of assortativity signature on robustness

Dartmouth researchers explored the type and number of connections in transcription factor networks (TFNs) to evaluate the role assortativity plays on robustness in a study published in PLOS Computational Biology in August.

30 Aug 2014

Preventing tentacle-like structures from forming can stop spread of cancer entirely

A new study from the research group of Dr. John Lewis at the University of Alberta (Edmonton, AB) and the Lawson Health Research Institute (London, ON) has confirmed that "invadopodia" play a key role in the spread of cancer. The study, published in Cell Reports, shows preventing these tentacle-like structures from forming can stop the spread of cancer entirely.

30 Aug 2014

Genetic News and Research

Project aims at establishing central biobank for development of new drugs

Researchers uncover intriguing link between heart attacks and protein

Scientists identify genetic mutations in endometrioid endometrial carcinoma

Artificial cells to devour undesirables: an interview with Dr. Takanari Inoue

Distinct features of COPD–asthma overlap syndrome identified

Measuring levels of sex hormones in patients' blood may identify risk of sudden cardiac arrest

Researchers identify different types of tuberculosis using new genetic barcode

Around 9.6% of women diagnosed with dry eye disease, treated with artificial tear eye drops

New approach to turn diseased cells into unique manufacturing sites for treating muscular dystrophy

White pill may help scientists learn why patients with cystic fibrosis have less exercise capacity

Coffee increases risk of prediabetes in young adults with hypertension

Concordia's subsidiary signs collaboration deal with Orphan Canada for PHOTOFRIN

Cepheid releases Xpert Flu/RSV XC for accurate determination of Flu A, Flu B and RSV infection

Finding could lead researchers to better understand development of psychiatric disorders

Flow through pain-sensing molecule helps worms adapt to pain

New genetic barcode helps identify different types of tuberculosis

Internal production of hydrogen peroxide can lead cells to exit cell cycle and become senescent

Special issue looks at how researchers use bioinformatics to understand plant form

Dartmouth researchers evaluate role of assortativity signature on robustness

Preventing tentacle-like structures from forming can stop spread of cancer entirely

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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