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Gene therapy may offer significant advantages in prevention of botulism exposure

The current method to treat acute toxin poisoning is to inject antibodies, commonly produced in animals, to neutralize the toxin. But this method has challenges ranging from safety to difficulties in developing, producing and maintaining the anti-serums in large quantities.

30 Aug 2014

Researchers find method to expand blood stem cells used to treat cancer patients

A team of scientists from the University of Colorado School of Medicine has reported the breakthrough discovery of a process to expand production of stem cells used to treat cancer patients.

30 Aug 2014

Researchers explore connections in TFNs to evaluate role assortativity plays on robustness

Dartmouth researchers explored the type and number of connections in transcription factor networks (TFNs) to evaluate the role assortativity plays on robustness in a study published in PLOS Computational Biology in August.

30 Aug 2014

UT Southwestern faculty awarded CPRIT grants to combat cancer

UT Southwestern Medical Center faculty have received 19 grants totaling more than $26 million from the Cancer Prevention and Research Institute of Texas to expand cancer screenings, investigate the effectiveness and viability for cancer therapies and radiation treatments, conduct research into cancer biology, and recruitment.

29 Aug 2014

Climate change threatens survival of Devils Hole pupfish

Climate change is hurting reproduction of the endangered Devils Hole pupfish, threatening the survival of this rare species that has numbered as few as 35 individuals, new research by the University of Nevada, Reno and Desert Research Institute shows.

29 Aug 2014

International consortium to accelerate collaborative multi-site trials of potential Ebola vaccine

A candidate Ebola vaccine could be given to healthy volunteers in the UK, The Gambia and Mali as early as September, as part of an series of safety trials of potential vaccines aimed at preventing the disease that has killed more than 1,400 people in the current outbreak in West Africa.

29 Aug 2014

NIH to start initial human testing of investigational Ebola vaccine next week

Initial human testing of an investigational vaccine to prevent Ebola virus disease will begin next week by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

29 Aug 2014

Changes in ADNP gene may provide further insight into causes of autism

A new study from Bradley Hospital has identified a genetic change in a recently identified autism-associated gene, which may provide further insight into the causes of autism. The study, now published online in the Journal of Medical Genetics, presents findings that likely represent a definitive clinical marker for some patients' developmental disabilities.

29 Aug 2014

Minnesota researchers develop animal research model for FSHD

Researchers at the University of Minnesota have developed an animal research model for facioscapulohumeral muscular dystrophy (FSHD) to be used for muscle regeneration research as well as studies of the effectiveness of potential therapies for FSHD.

29 Aug 2014

TGen to lead first-in-patient clinical trial studies to test novel drugs for glioblastoma

SIn 2012, The Ben & Catherine Ivy Foundation awarded $10 million in grants for two groundbreaking brain cancer research projects at the Translational Genomics Research Institute. One of those projects has officially received the final regulatory approval from University of California, San Francisco, which means patient enrollment for the trial can begin.

29 Aug 2014

Pharmatech begins enrollment for AccessPPM program

Pharmatech initiated enrollment for its AccessPPM program after a two-year investment into this game-changing method for matching cancer patients to cancer clinical trials.

29 Aug 2014

School nurses reach 98% of students in U.S. public schools to diagnose primary immunodeficiency

School nurses reach 98 percent of the 50,000,000 students in U.S. public schools, grades k-12, and are uniquely positioned to facilitate the early diagnosis of serious medical conditions such as primary immunodeficiency (PI).

28 Aug 2014

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Amgen today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration for evolocumab seeking approval for the treatment of high cholesterol.

28 Aug 2014

Gene variants linked to overactive bladder and prolapse in women

A systematic review and meta-analysis of genetic association studies reveals a number of genetic variations associated with overactive bladder and pelvic organ prolapse in women.

28 Aug 2014

Isis Pharmaceuticals begins ISIS-APOCIIIRx Phase 3 study in FCS patients

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 3 study evaluating ISIS-APOCIIIRx in patients with familial chylomicronemia syndrome (FCS). FCS is a rare orphan disease, characterized by extremely high triglyceride levels, that affects an estimated 3,000 to 5,000 patients worldwide.

28 Aug 2014

Scientists solve mystery of why specific signaling pathway can be linked with alcohol dependence

Scientists at The Scripps Research Institute (TSRI) have solved the mystery of why a specific signaling pathway can be associated with alcohol dependence.

28 Aug 2014

Loyola University Medical Center redesignated as Level III Perinatal Center

Loyola University Medical Center has been redesignated as a Level III Perinatal Center by the Illinois Department of Public Health.

28 Aug 2014

Research report: Orphan Diseases Partnering Terms and Agreements

The Orphan Diseases Partnering Terms and Agreements report provides an understanding and access to the orphan diseases partnering deals and agreements entered into by the worlds leading healthcare companies.

28 Aug 2014

Report on Co-development Terms & Agreements in Pharma, Biotech and Diagnostics

The Co-development Terms and Agreements in Pharma, Biotech and Diagnostics report provides comprehensive understanding and unprecedented access to the co-development deals and agreements entered into by the worlds leading life science companies.

28 Aug 2014

Study: Many HIV infected African-Americans may not be receiving effective doses of maraviroc drug

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study from Johns Hopkins suggests. The initial dosing studies, completed before the drug was licensed in 2007, included mostly European-Americans, who generally lack a protein that is key to removing maraviroc from the body.

28 Aug 2014

Genetic News and Research

Gene therapy may offer significant advantages in prevention of botulism exposure

Researchers find method to expand blood stem cells used to treat cancer patients

Researchers explore connections in TFNs to evaluate role assortativity plays on robustness

UT Southwestern faculty awarded CPRIT grants to combat cancer

Climate change threatens survival of Devils Hole pupfish

International consortium to accelerate collaborative multi-site trials of potential Ebola vaccine

NIH to start initial human testing of investigational Ebola vaccine next week

Changes in ADNP gene may provide further insight into causes of autism

Minnesota researchers develop animal research model for FSHD

TGen to lead first-in-patient clinical trial studies to test novel drugs for glioblastoma

Pharmatech begins enrollment for AccessPPM program

School nurses reach 98% of students in U.S. public schools to diagnose primary immunodeficiency

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Gene variants linked to overactive bladder and prolapse in women

Isis Pharmaceuticals begins ISIS-APOCIIIRx Phase 3 study in FCS patients

Scientists solve mystery of why specific signaling pathway can be linked with alcohol dependence

Loyola University Medical Center redesignated as Level III Perinatal Center

Research report: Orphan Diseases Partnering Terms and Agreements

Report on Co-development Terms & Agreements in Pharma, Biotech and Diagnostics

Study: Many HIV infected African-Americans may not be receiving effective doses of maraviroc drug

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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