Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists develop new approach to combating antibiotic resistance

A team of researchers have developed a way of preventing the transfer of antibiotic resistance genes between bacteria.

22 Nov 2017

Alzheimer's Tau protein interacts with cell membranes and forms toxic complexes

The brains of patients with Alzheimer's disease contain characteristic tangles inside neurons. These tangles are formed when a protein called Tau aggregates into twisted fibrils. As a result, the neurons' transport systems disintegrate, essential nutrients can't move through, and the cells begin to die, affecting the brain's functions and giving rise to the disease's symptoms.

22 Nov 2017

Protein synthesis regulatory factor vital for long-term memory formation

The research group of Associate Professor Nobuyuki Shiina of the National Institute for Basic Biology have revealed that the function of RNG105 (aka Caprin1) is essential for the formation of long-term memory.

22 Nov 2017

CF patients in the U.S. show faster rate of improvement in lung function and nutrition

New research comparing cystic fibrosis patients in the United States and Canada showed that, although the patients' nutritional status and lung function improved in both countries over the period from 1990 to 2013, the rate of improvement was faster in the United States.

22 Nov 2017

Oncologists find new biomarker for breast cancer having poor prognosis

With the support of the FWF, an oncologist found a biomarker for breast cancer having a poor prognosis and developed two viable methods to detect it in tissue samples.

22 Nov 2017

New video shows how to use solid state filter microplate for LC/MS sample preparation

Porvair Sciences has published an informative video that shows how to use a solid-state filter microplate to remove interfering proteins from serum, plasma or even whole blood samples prior to analysis by Liquid Chromatography / Mass Spectrometry.

From Porvair Sciences Limited 22 Nov 2017

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

After years of rigorous research, a team of scientists has identified the genetic engine that drives a rare form of liver cancer. The findings offer prime targets for drugs to treat the usually lethal disease, fibrolamellar hepatocellular carcinoma (FL-HCC), which mainly strikes adolescents and young adults.

22 Nov 2017

Researchers uncover how rogue immune cells gain access to neurons in multiple sclerosis

Drug designers working on therapeutics against multiple sclerosis should focus on blocking two distinct ways rogue immune cells attack healthy neurons, according to a new study in the journal Cell Reports.

21 Nov 2017

High-fat diet during lactation alters RNA activity in breast milk, research suggests

New research suggests that following a high-fat diet during lactation - regardless of diet during pregnancy - alters RNA activity in breast milk. The changes in genetic material may increase the risk of metabolic disorders such as type 2 diabetes in offspring. The article is published ahead of print in Physiological Genomics.

21 Nov 2017

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Columbia University biologists have revealed a mechanism by which bacterial cells in crowded, oxygen-deprived environments access oxygen for energy production, ensuring survival of the cell. The finding could explain how some bacteria, such as Pseudomonas aeruginosa (P. aeruginosa), are able to thrive in oxygen-poor environments like biofilms and resist antibiotics.

21 Nov 2017

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

University of Colorado Boulder researchers have discovered a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases by inhibiting a protein instrumental in prompting the body to start attacking its own tissue.

21 Nov 2017

Scientists develop novel technology that uses CRISPR to map genetic mutations

A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered.

21 Nov 2017

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts.

21 Nov 2017

Diabetes patients’ immune system can regulate insulin production

Inflammation processes are responsible for the failure of insulin production in diabetes patients. The patients' own immune systems can contribute to treatment of this disease: researchers at the University of Basel and University Hospital Basel have found a feedback mechanism that could help maintain insulin production in overweight sufferers, as they report in the journal Immunity.

21 Nov 2017

Study finds sensors to detect biomarkers

A new study conducted at Purdue University suggests that small vibrating sensors or microelectromechanical resonators can be used to identify biological markers in small amounts of blood. This method is expected to be useful for detecting a myriad of diseases, infections, and different medical conditions in their early stages.

21 Nov 2017

New mechanism in cancer cells to disarm attacking immune cells, study reveals

A new study, published in the Journal of Clinical Investigation, identified a substance Gdf-15, which is secreted by pancreatic cancer cells and shields cancerous cells from attack by immune cells known as macrophages.

21 Nov 2017

Sensors for identifying biomarkers could help detect myriad of diseases at early stages

Purdue University researchers have found a method of identifying biological markers in small amounts of blood that they believe could be used to detect a myriad of diseases, infections and different medical conditions at early stages.

21 Nov 2017

Heart disease risk factors linked to walking difficulties in people under age of 78

Problems with balance, walking speed, and muscle strength become more common as we age, and can lead to disability. In fact, studies show that for older adults, having a slower walking speed can help predict chronic illness, hospitalization, and even death.

21 Nov 2017

UVA scientists working to find end-around method to stop triple-negative breast cancer

So-called "triple-negative" breast cancer is a particularly aggressive and difficult-to-treat form. It accounts for only about 10 percent of breast cancer cases, but is responsible for about 25 percent of breast cancer fatalities.

20 Nov 2017

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

Protein News and Research

Further Reading

Scientists develop new approach to combating antibiotic resistance

Alzheimer's Tau protein interacts with cell membranes and forms toxic complexes

Protein synthesis regulatory factor vital for long-term memory formation

CF patients in the U.S. show faster rate of improvement in lung function and nutrition

Oncologists find new biomarker for breast cancer having poor prognosis

New video shows how to use solid state filter microplate for LC/MS sample preparation

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

Researchers uncover how rogue immune cells gain access to neurons in multiple sclerosis

High-fat diet during lactation alters RNA activity in breast milk, research suggests

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

Scientists develop novel technology that uses CRISPR to map genetic mutations

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Diabetes patients’ immune system can regulate insulin production

Study finds sensors to detect biomarkers

New mechanism in cancer cells to disarm attacking immune cells, study reveals

Sensors for identifying biomarkers could help detect myriad of diseases at early stages

Heart disease risk factors linked to walking difficulties in people under age of 78

UVA scientists working to find end-around method to stop triple-negative breast cancer

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

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