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New study to measure effectiveness of Vitamin B12 in preventing gestational diabetes

New MRC-funded research underway to measure effectiveness of Vitamin B12 supplement in preventing gestational diabetes in mothers and obestity in later life.

9 May 2012

Dilp8 provides an important signal to slow body growth and delay insect development

Two independent groups of researchers have identified a hormone that is responsible for keeping the growth and development of insects on track. The results, which are reported in the journal Science, suggest that Dilp8 provides an important signal to slow body growth and delay insect development.

5 May 2012

New light on many biological differences between individual breast cancers

New findings presented at Europe's leading breast cancer translational research conference this year shed new light on the many biological differences between individual breast cancers.

4 May 2012

NPS first quarter net loss increases to $10.6 million

NPS Pharmaceuticals, Inc., a specialty pharmaceutical company developing orphan therapeutics for rare gastrointestinal and endocrine disorders, today reported its results for the first quarter of 2012.

4 May 2012

Potential ways for doctors to improve hormone receptor-positive breast cancer treatment

American and Spanish researchers have found potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests, as they report at the 4th IMPAKT Breast Cancer Conference.

4 May 2012

ADM hormone plays a significant role in tubal ectopic pregnancies

Tubal ectopic pregnancy (TEP) is currently the leading cause of pregnancy-related deaths during the first trimester and a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) shows that the hormone adrenomedullin (ADM) may help predict this condition.

3 May 2012

Study finds possible link between ghrelin hormone and hedonic eating

When eating is motivated by pleasure, rather than hunger, endogenous rewarding chemical signals are activated which can lead to overeating, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

3 May 2012

Smokers with variants in specific genes at increased risk for hot flashes

Women who smoke and carry specific variations in the genes that impact their metabolism are at higher risk of developing hot flashes in comparison with smokers who do not carry these gene variants, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

3 May 2012

Endocrine Society and its Hormone Health Network release ‘Menopause Map’

Women going through menopause now have a first-of-its-kind interactive guide to help them better understand their menu of treatment options, including whether hormone therapy may be right for them. The Endocrine Society and its Hormone Health Network today released the "Menopause Map," an online tool to help women and their doctors discuss which hormonal and non-hormonal treatment options would be most effective and safe to relieve the sometimes debilitating symptoms of menopause.

2 May 2012

Trovagene completes PCR assay development for detection of K-RAS mutations

Trovagene, Inc., a developer of trans-renal molecular diagnostics, announced today that the Company has successfully completed the analytical development of digital PCR assays for the detection of the most prevalent K-RAS mutations, which are, according to recent estimates, observed in more than 90% of pancreatic cancers, and in 23% of all solid tumors.

30 Apr 2012

IMPAKT 2012 breast cancer conference to focus on four major areas

"Basic science and clinical medicine move at different pace because they follow different paths. Both however aim at improving strategies to manage cancer patients. We need to efficiently translate the good things from basic science and efficiently implement them in the clinic."

26 Apr 2012

CEHC develops list of ten chemicals that contribute to autism, learning disabilities

An editorial published today in the prestigious journal Environmental Health Perspectives calls for increased research to identify possible environmental causes of autism and other neurodevelopmental disorders in America's children and presents a list of ten target chemicals including which are considered highly likely to contribute to these conditions.

26 Apr 2012

Cadmium exposure can cause progression of aggressive breast cancer

Studies by researchers at Dominican University of California show that breast cancer cells become increasingly aggressive the longer they are exposed to small concentrations of cadmium, a heavy metal commonly found in cosmetics, food, water and air particles.

24 Apr 2012

Potential for gallbladder tissue as source for multipotential stem cells

A new study presented today at the International Liver Congress- 2012 indicates the potential for gallbladder tissue (which is routinely discarded from organ donors and surgical interventions) to be a highly available candidate source for multipotential stem cells.

20 Apr 2012

Fluorescent fish shows oestrogenic chemicals’ impact on human body

Understanding the damage that pollution causes to both wildlife and human health is set to become much easier thanks to a new green-glowing zebrafish. Created by a team from the University of Exeter, the fish makes it easier than ever before to see where in the body environmental chemicals act and how they affect health.

19 Apr 2012

Air pollution can contribute to obesity in children

Overall, 17% of children in the United States are obese, and in inner-city neighborhoods, the prevalence is as high as 25%. While poor diets and physical inactivity are the main culprits, there is new evidence that air pollution can play a role.

17 Apr 2012

Disruption of key cellular functions produces physiologic and behavioral responses

Two Massachusetts General Hospital (MGH)-based research teams, along with a group from the University of California at San Diego, have discovered that animals have a previously unknown system for detecting and responding to pathogens and toxins. In three papers published in the journals Cell and Cell Host & Microbe, the investigators describe finding evidence that disruptions to the core functions of animal cells trigger immune and detoxification responses, along with behavioral changes.

16 Apr 2012

Aberrations in translation regulators linked with hormone receptor-positive breast cancer survival

Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR Annual Meeting 2012.

2 Apr 2012

Blood levels of PCBs in polar bear cubs appear to have dropped

It's never been easy to be a polar bear. They may have to go months without eating. Their preferred food, seal, requires enormous luck and patience to catch. Add to that the melting of Arctic sea ice due to climate change, and the poisoning of the Arctic by toxic chemicals, and it's easy to see why polar bears worldwide are in trouble.

30 Mar 2012

BPA shows tangible effects on health endpoints at high dosage levels

Endocrine-disrupting chemicals (EDCs)-such as BPA-can show tangible effects on health endpoints at high dosage levels, yet those effects do not predict how EDCs will affect the endocrine system at low doses, according to a recent study accepted for publication in The Endocrine Society's Endocrine Reviews.

30 Mar 2012