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Chi-Med announces initiation of Phase III sulfatinib registration trial in patients with NETs in China

Hutchison China MediTech Limited today announces that Hutchison MediPharma Limited, its drug R&D subsidiary, has initiated SANET-ep, a Phase III sulfatinib (HMPL-012) registration trial in China in patients with extra-pancreatic neuroendocrine tumors ("NETs"), which are all non-pancreatic NETs, including, for example, NETs originating in the lymph, lung and across the gastrointestinal tract.

18 Dec 2015

New nanotechnology approach could transform gliomas from death sentence into treatable condition

An MRI contrast agent that can pass through the blood-brain barrier will allow doctors to detect deadly brain tumors called gliomas earlier, say Penn State College of Medicine researchers. This ability opens the door to make this fatal cancer treatable.

18 Dec 2015

Findings show promising evidence for creating broad-spectrum antiviral

UW researchers working in collaboration with Kineta Inc. and the University of Texas at Galveston have shown that making a drug-like molecule to turn on innate immunity can induce genes to control infection in several -known viruses.

18 Dec 2015

Case Western scientist to lead a pair of studies to develop more effective treatment for CF

A scientist at Case Western Reserve University Frances Payne Bolton School of Nursing will lead a pair of studies to develop more effective treatment for symptoms of cystic fibrosis (CF), a life-threatening genetic disease that causes persistent lung infections and progressively limits the ability to breathe.

18 Dec 2015

New discovery could open door to potential treatment for West Nile virus and Dengue virus infections

A new discovery from the University of Alberta's Faculty of Medicine & Dentistry could open the door to one day treat or prevent diseases caused by West Nile virus and Dengue virus infections.

18 Dec 2015

UT Southwestern researchers find potential mechanism to prevent epileptic seizures following TBI

UT Southwestern Medical Center researchers have found that halting production of new neurons in the brain following traumatic brain injury can help reduce resulting epileptic seizures, cognitive decline, and impaired memory.

18 Dec 2015

Study examines effect of nonoperative treatment for appendicitis

It is too early to change the standard treatment of appendicitis in U.S. adults to initial antibiotic therapy only, rather than surgical removal of the appendix, or appendectomy, authors of a new systematic review study conclude.

18 Dec 2015

Toronto researchers reveal how opioids interfere with breathing mechanism

University of Toronto researchers on a quest to make opioid drugs less lethal have discovered a window of opportunity: a tiny channel in the brain where opioids interfere with the breathing mechanism.

18 Dec 2015

Scientists identify overlooked consequence of spatial separation of cells into nucleus, cytoplasm

Genetically identical cells do not always behave the same way. According to the accepted theory, the reason are random molecular processes - known as random noise. For decades this view has been underpinned by numerous experiments and theoretical models.

18 Dec 2015

Harvard scientists link specific neurotransmitter in the brain with autistic behavior

In a discovery that could offer valuable new insights into understanding, diagnosing and even treating autism, Harvard scientists for the first time have linked a specific neurotransmitter in the brain with autistic behavior.

18 Dec 2015

New study sheds light on the molecular basis of memory and learning

The brain still harbours many unknowns. Basically, it is assumed that it stores experiences by altering the connections between brain cells. This ability to adapt - which is also called "plasticity" - provides the basis for memory and learning, which is the ability to draw conclusions from memories. On a molecular scale these changes are mediated by modifications of expression of specific genes that as required strengthen or weaken the connections between the brain cells.

18 Dec 2015

Stem cell therapy not significantly better than conventional treatment for Crohn's disease

A clinical trial to test the effectiveness of a stem cell therapy among adults with difficult to treat Crohn's disease has found it is not significantly better than conventional treatment in producing sustained disease remission after one year.

18 Dec 2015

LifeVest wearable cardioverter defibrillator approved for children at risk for sudden cardiac arrest

The U.S. Food and Drug Administration today approved a new indication for the LifeVest wearable cardioverter defibrillator. The LifeVest is approved for certain children who are at risk for sudden cardiac arrest, but are not candidates for an implantable defibrillator due to certain medical conditions or lack of parental consent.

17 Dec 2015

Novel strategies on the way for difficult-to-treat head and neck cancer

Novel strategies are on the way for difficult-to-treat and advanced head and neck cancer, the most heterogeneous group of malignancies which are generally associated with poor survival, and encouraging results have been presented at the first ESMO Asia 2015 Congress in Singapore.

17 Dec 2015

Ketogenic diet may be effective in treating schizophrenia

Research by James Cook University scientists has found a diet favoured by body-builders may be effective in treating schizophrenia.

17 Dec 2015

Zoledronate drug can protect stem cells from ageing

Stem cells can be protected from the effects of ageing by a drug currently used to treat patients with osteoporosis, a breakthrough study has found.

17 Dec 2015

Research project explores use of nanoparticles as a way to disinfect wounds

Infections contracted during surgical operations are a serious healthcare problem, leading to death in some cases. Now, a research project at the University of Huddersfield is investigating the use of nanoparticles as a way to disinfect wounds. It could prove to be much more effective than existing techniques because the particles would be tiny enough to enter the skin via hair follicles, ensuring much better penetration of the area affected by surgery.

17 Dec 2015

Study examines whether pregnant woman can take antidepressants during pregnancy

Should a pregnant woman stop taking antidepressants during her pregnancy? The Journal of the American Medical Association has published a study showing the risk of autism doubles (from 1% to 2%) for children of women who use antidepressants, like Zoloft and Prozac. Max Wiznitzer, MD, pediatric neurologist at UH Rainbow Babies & Children's Hospital, stresses, even if the study proves correct, the vast majority of babies exposed to antidepressants in the second and third trimesters will not develop autism.

17 Dec 2015

Berkeley Lab researchers develop new mouse model for most common form of breast cancer

The first clinically-relevant mouse model of human breast cancer to successfully express functional estrogen receptor positive (ER+) adenocarcinomas has been developed by researchers at Lawrence Berkeley National Laboratory.

17 Dec 2015

New funding supports research on new and improved drug treatments for tuberculosis, malaria

University of Toronto and McGill University scientists are leading an international partnership to discover new and improved drug treatments for tuberculosis, malaria and neglected tropical diseases -- thanks to a contribution from Merck Canada Inc., as well as an additional $5 million supplement to a grant from the Bill & Melinda Gates Foundation.

17 Dec 2015

Drugs News and Research

Chi-Med announces initiation of Phase III sulfatinib registration trial in patients with NETs in China

New nanotechnology approach could transform gliomas from death sentence into treatable condition

Findings show promising evidence for creating broad-spectrum antiviral

Case Western scientist to lead a pair of studies to develop more effective treatment for CF

New discovery could open door to potential treatment for West Nile virus and Dengue virus infections

UT Southwestern researchers find potential mechanism to prevent epileptic seizures following TBI

Study examines effect of nonoperative treatment for appendicitis

Toronto researchers reveal how opioids interfere with breathing mechanism

Scientists identify overlooked consequence of spatial separation of cells into nucleus, cytoplasm

Harvard scientists link specific neurotransmitter in the brain with autistic behavior

New study sheds light on the molecular basis of memory and learning

Stem cell therapy not significantly better than conventional treatment for Crohn's disease

LifeVest wearable cardioverter defibrillator approved for children at risk for sudden cardiac arrest

Novel strategies on the way for difficult-to-treat head and neck cancer

Ketogenic diet may be effective in treating schizophrenia

Zoledronate drug can protect stem cells from ageing

Research project explores use of nanoparticles as a way to disinfect wounds

Study examines whether pregnant woman can take antidepressants during pregnancy

Berkeley Lab researchers develop new mouse model for most common form of breast cancer

New funding supports research on new and improved drug treatments for tuberculosis, malaria

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics

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