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U-M lab receives $13.2 million NIDA grant to optimize interventions for substance abuse disorders

A University of Michigan lab focused on developing cutting-edge methods to inform effective interventions for drug abuse, HIV and other chronic conditions has been awarded a $13.2 million grant from the National Institute on Drug Abuse.

28 Sep 2021

Researchers find cliché-sounding behavioral patterns from first coronavirus lockdown

In a crisis, women make significantly longer phone calls and adhere more closely to governmental measures than men; men are less likely to have their mobility restricted and return to normal more quickly than women.

28 Sep 2021

An ad’s charge that price haggling would ‘swipe $500 billion from Medicare’ is incorrect

The advertisement opens with a doctor sitting across from his patient and holding a prescription drug pill bottle. "You want to continue with this medication?" the doctor asks while an older patient nods.

28 Sep 2021

Southampton researchers invent new way to generate cartilage tissue from stem cells

Researchers at the University of Southampton have invented a new way to generate human cartilage tissue from stem cells. The technique could pave the way for the development of a much-needed new treatment for people with cartilage damage.

28 Sep 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021

Primary sclerosing cholangitis: Therapy with synthetic bile acid acts directly on the immune system

Primary Sclerosing Cholangitis (PSC) is a rare, chronic inflammatory disease of the bile ducts and is difficult to treat. Studies conducted by the Division of Gastroenterology and Hepatology at MedUni Wien under the guidance of Michael Trauner (Department of Internal Medicine III) were able to show positive effects from the administration of synthetically produced bile acids and bile acid receptor agonists.

28 Sep 2021

Novel polyclonal antibody therapy meets the criteria for graduation to phase 3 in ACTIV-2 trial

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, which recently expanded its focus to include evaluating outpatient treatment for COVID-19, today announced that SAB-185, a novel polyclonal antibody therapy, has demonstrated safety and efficacy in phase 2 that meet the criteria for graduation to phase 3 in the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial (ACTG A5401).

28 Sep 2021

Researchers release guidance to address pathology aspects in clinical trial protocols

An international group of cancer researchers, led by the National Cancer Research Institute's (NCRI) Cellular Molecular Pathology Initiative (CMPath), has published guidance to address the variability in how pathology is planned and delivered in clinical trials.

28 Sep 2021

Study maps hotspots of low-value care use at individual health systems

Researchers estimate that up to $101 billion in health care spending is wasted each year due to over-treatment or the delivery of "low-value care." Low-value care includes a wide array of tests and treatments that are medically unnecessary and for which the potential for harm outweigh the potential for benefit. While researchers have charted the ongoing use of low-value care on national and regional levels, little research exists on how health systems across the country use low-value care and how they compare to each other.

28 Sep 2021

Researchers discover working mechanism of potential drug targets for COVID-19

A team of international researchers, including McGill Professor Stéphane Laporte, have discovered the working mechanism of potential drug targets for various diseases such as cancer, rheumatoid arthritis, and even COVID-19.

28 Sep 2021

COVID Moonshot receives key funding to accelerate drug discovery efforts

The COVID Moonshot, a non-profit, open-science consortium of scientists from around the world dedicated to the discovery of globally affordable and easily-manufactured antiviral drugs against COVID-19 and future viral pandemics has received key funding of £8 million from Wellcome, on behalf of the Covid-19 Therapeutics Accelerator.

28 Sep 2021

New discovery greatly improves detection of HPV in the bloodstream

Princess Margaret Cancer Centre researchers have made new findings which greatly improve detection of the human papillomavirus (HPV) in the bloodstream and could further hone precision treatment of the illness.

27 Sep 2021

Pfizer-BioNTech’s COVID-19 vaccine appears effective against SARS-CoV-2 mu variant

Researchers in Japan have conducted a study showing that the vaccine developed by Pfizer-BioNTech to protect against coronavirus disease 2019 (COVID-19) seems to be adequately effective against the B.1.621 (mu) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Sep 2021

Drug treatment decreases risk for severe COVID-19 outcomes in patients with Type 2 diabetes

A type of drug already used to treat obesity and Type 2 diabetes, when taken six months prior to the diagnosis of COVID-19, was associated with a decreased risk of hospitalization, respiratory complications and death in COVID-19 patients with Type 2 diabetes, according to researchers at Penn State College of Medicine.

27 Sep 2021

Nemours receives NIH grant to foster COVID-19 vaccine uptake among children in Black and Latino communities

Researchers at Nemours Children's Hospital, Delaware, as part of a public-private partnership, have received a National Institutes of Health grant supplement through the Delaware Clinical and Translational Research ACCEL Program to develop and test an approach to foster uptake of the COVID-19 vaccine among children in Black and Latino communities.

27 Sep 2021

Bouts of moderate to vigorous exercise can drastically improve a person's fitness

Exercise is healthy. That is common knowledge. But just how rigorous should that exercise be in order to really impact a person's fitness level? And, if you sit all day at a desk, but still manage to get out and exercise, does that negate your six, seven, or eight hours of sedentary behavior?

27 Sep 2021

Researchers investigate dynamic changes in mosquitoes and their viromes in Wuhan during 2020

Announcing a new article publication for Zoonoses journal. Researchers from Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Wuhan, China, University of Chinese Academy of Sciences, Beijing, China, Jinan University, Shenzhen, China and Shanghai Jiao Tong University School of Medicine, Shanghai, China consider dynamic surveillance of mosquitoes and their viromes in Wuhan during 2020.

27 Sep 2021

Expanded dialysis can improve quality of life in chronic kidney disease patients

In a published study, a hospital research team from Lawson Health Research Institute has found that expanded dialysis, a new method that removes a broader range of toxins from the body, can improve quality of life in chronic kidney disease patients who struggle with the side effects of traditional dialysis.

27 Sep 2021

Withdrawal from psychostimulants alters functional architecture and patterns in the brain

Addictive psychostimulants, from nicotine in cigarettes to illicit drugs like methamphetamine and cocaine, affect different regions of the brain. The same is believed true during withdrawal; finding a common brain pathway has proved elusive.

27 Sep 2021

$6 million CDC grant to support U-M researchers in reducing youth firearm violence

Middle- and high school-age children across the United States are more likely to die as the result of a firearm injury than from any other single cause of death.

27 Sep 2021

Medicine News and Research

U-M lab receives $13.2 million NIDA grant to optimize interventions for substance abuse disorders

Researchers find cliché-sounding behavioral patterns from first coronavirus lockdown

An ad’s charge that price haggling would ‘swipe $500 billion from Medicare’ is incorrect

Southampton researchers invent new way to generate cartilage tissue from stem cells

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

Primary sclerosing cholangitis: Therapy with synthetic bile acid acts directly on the immune system

Novel polyclonal antibody therapy meets the criteria for graduation to phase 3 in ACTIV-2 trial

Researchers release guidance to address pathology aspects in clinical trial protocols

Study maps hotspots of low-value care use at individual health systems

Researchers discover working mechanism of potential drug targets for COVID-19

COVID Moonshot receives key funding to accelerate drug discovery efforts

New discovery greatly improves detection of HPV in the bloodstream

Pfizer-BioNTech’s COVID-19 vaccine appears effective against SARS-CoV-2 mu variant

Drug treatment decreases risk for severe COVID-19 outcomes in patients with Type 2 diabetes

Nemours receives NIH grant to foster COVID-19 vaccine uptake among children in Black and Latino communities

Bouts of moderate to vigorous exercise can drastically improve a person's fitness

Researchers investigate dynamic changes in mosquitoes and their viromes in Wuhan during 2020

Expanded dialysis can improve quality of life in chronic kidney disease patients

Withdrawal from psychostimulants alters functional architecture and patterns in the brain

$6 million CDC grant to support U-M researchers in reducing youth firearm violence

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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