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Phase 1 BelCHOP study shows belinostat and CHOP chemo regimen as first-line treatment for PTCL

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations and a primary focus in Hematology and Oncology, and Onxeo S.A., an innovative company specializing in the development of orphan oncology drugs, today jointly announced the results from their Phase 1 combination trial of belinostat (Beleodaq) with the CHOP (Cyclophosphamide, Hydroxyl-doxorubicin; Vincristine, and Prednisone) chemotherapy regimen as first-line treatment for newly diagnosed peripheral T-cell lymphoma (PTCL).

8 Dec 2015

Gallstones, statins increase risk of acute pancreatitis, shows study

Idiopathic pancreatitis is often caused by small gallstones that are difficult to observe prior to surgery, shows a study from the University of Eastern Finland. Small gallstones were found in surgery from two out of three idiopathic pancreatitis patients.

8 Dec 2015

Lancet study compares prices of new cancer drugs in high-income countries

The price of new cancer drugs varies widely (from 28% to 388%) between high-income countries in Europe, Australia, and New Zealand, new research published in The Lancet Oncology has found.

8 Dec 2015

Study shows promise for cord blood-derived natural killer cells in multiple myeloma patients

A first-in-human Phase I study of multiple myeloma patients combined expanded cord blood-derived natural killer cells with transplantation of a patient's own stem cells and high-dose chemotherapy with little or none of the side effects seen with current treatments.

8 Dec 2015

Researchers reveal potential for exploring new treatment options for triple-negative breast cancer

Researchers from Caris Life Sciences and Fox Chase Cancer Center – Temple Health announced the presentation of two studies revealing the potential for exploring new therapeutic options for triple-negative breast cancer (TNBC) at the 2015 San Antonio Breast Cancer Symposium.

7 Dec 2015

XARELTO reduces rates of major bleeding, recurrent blood clots in people with deep vein thrombosis

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced the results from their real-world study XALIA showing that, in people with deep vein thrombosis (DVT), the rates of major bleeding and recurrent blood clots for XARELTO (rivaroxaban) in routine clinical practice were generally consistent with those observed in Phase 3 research.

7 Dec 2015

Scientists decipher details of cloaking proteins that protect the toxin that causes botulism

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators at Stony Brook University and the Institute of Advanced Sciences in Dartmouth, Massachusetts, have discovered new details about how "cloaking" proteins protect the toxin that causes botulism, a fatal disease caused most commonly by consuming improperly canned foods.

7 Dec 2015

Children suffering from neuroblastoma may benefit from potential new treatment

Children suffering from a cancer of the nervous system could benefit from a potential new treatment, thanks to an international team led by researchers at the University of Kent and at the Institute of Medical Virology at the Goethe-University, Frankfurt am Main, Germany.

7 Dec 2015

New approaches to treating leukemia, lymphoma and myeloma

New, highly targeted treatment approaches for leukemia, lymphoma, and myeloma to be presented today at the 57th American Society of Hematology Annual Meeting and Exposition represent a tremendous expansion of oral and intravenous therapy options for patients with blood cancers.

7 Dec 2015

Reduced antibiotic prescribing associated with lower patient satisfaction

Reduced antibiotic prescribing is associated with lower patient satisfaction on the national General Practice Patient Survey, according to a new study by King's College London. The study found a 25 per cent lower rate of antibiotic prescribing by a GP practice corresponded to a 5-6 point reduction on GP satisfaction rankings.

7 Dec 2015

OphthaliX completes patient enrollment in CF101 Phase II trial for treatment of glaucoma

OphthaliX Inc., a clinical-stage company focused on developing therapeutic products for the treatment of ophthalmic disorders and a subsidiary of Can-Fite BioPharma Ltd., announced today that it has completed patient enrollment for its Phase II trial of CF101 in the treatment of glaucoma.

7 Dec 2015

Yale study identifies how myeloma cells escape treatment

One of the biggest questions about the treatment of multiple myeloma, a form of blood cancer, is why nearly all patients treated with current therapies eventually suffer relapse. A Yale Cancer Center study may have solved this mystery by identifying how cancer cells escape treatment, leading to recurrence.

7 Dec 2015

Risk of dementia decreasing? An interview with Professor Carol Brayne, University of Cambridge

In this analysis we brought together the few European studies that have looked, within geographical areas, at the prevalence or incidence of dementia in the population aged 65 and over.

7 Dec 2015

New GASMAS-based technique shows promise for non-invasive sinusitis diagnostics

A team of scientists from the South China Normal University (Guangzhou, China) and the Lund University (Sweden) led by Sune Svanberg now presents a new approach for a non-intrusive optical technique for human sinus realtime diagnostics that could be developed into a cost-effective, easy-to-use hand-held instrument.

7 Dec 2015

WHO highlights need to expand antiretroviral therapy, reverse HIV epidemic on World AIDS Day

On World AIDS Day the World Health Organization emphasizes that expanding antiretroviral therapy to all people living with HIV is key to ending the AIDS epidemic within a generation.

7 Dec 2015

Researchers partner to help personalize cancer care

Researchers at the University of Iowa College of Dentistry are partnering with a private company to develop computer simulations that can help personalize cancer care by predicting how a patient will respond to a drug treatment.

7 Dec 2015

Neoadjuvant chemotherapy can stimulate evolution of breast cancer tumor

Russian scientists have found that neoadjuvant chemotherapy in patients with breast cancer can stimulate evolution of the tumor. The results of the research conducted by Nicholay Litvyakov, D.Sc. at Cancer Research Institute, Head of the Tumor Virology Laboratory, and TSU researcher Marina Ibragimova, were published in "Siberian Journal of Oncology."

1 Dec 2015

$Reduced bone mass puts critically ill patients at greater risk for fractures$

Reduced bone mass puts critically ill patients at greater risk for fractures

One year after being hospitalized in intensive care, patients have reduced bone mass that puts them at greater risk for fractures, according to a new study published online ahead of print in the American Journal of Respiratory and Critical Care Medicine.

1 Dec 2015

Innovative compound with anti-MRSA qualities may help develop new class of antibiotics

With global health services increasingly worried about the rise of antibiotic resistant diseases, researchers at Maynooth University have discovered a compound whose anti-MRSA qualities pave the way for the development of a new class of antibiotics.

1 Dec 2015

WHO recommends new strategies to treat HIV patients, reduce new infections

The world is poised to end the AIDS epidemic by 2030 – provided it can accelerate the pace of progress achieved globally over the past 15 years, according to a new World Health Organization (WHO) report.

1 Dec 2015

Drugs News and Research

Phase 1 BelCHOP study shows belinostat and CHOP chemo regimen as first-line treatment for PTCL

Gallstones, statins increase risk of acute pancreatitis, shows study

Lancet study compares prices of new cancer drugs in high-income countries

Study shows promise for cord blood-derived natural killer cells in multiple myeloma patients

Researchers reveal potential for exploring new treatment options for triple-negative breast cancer

XARELTO reduces rates of major bleeding, recurrent blood clots in people with deep vein thrombosis

Scientists decipher details of cloaking proteins that protect the toxin that causes botulism

Children suffering from neuroblastoma may benefit from potential new treatment

New approaches to treating leukemia, lymphoma and myeloma

Reduced antibiotic prescribing associated with lower patient satisfaction

OphthaliX completes patient enrollment in CF101 Phase II trial for treatment of glaucoma

Yale study identifies how myeloma cells escape treatment

Risk of dementia decreasing? An interview with Professor Carol Brayne, University of Cambridge

New GASMAS-based technique shows promise for non-invasive sinusitis diagnostics

WHO highlights need to expand antiretroviral therapy, reverse HIV epidemic on World AIDS Day

Researchers partner to help personalize cancer care

Neoadjuvant chemotherapy can stimulate evolution of breast cancer tumor

Reduced bone mass puts critically ill patients at greater risk for fractures

Innovative compound with anti-MRSA qualities may help develop new class of antibiotics

WHO recommends new strategies to treat HIV patients, reduce new infections

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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