Genetic News and Research

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Ovarian cancer screening may not be needed on routine basis for all women says panel

In its latest review since 2004 of the benefits and harms of ovarian cancer screening, the United States Preventive Services Task Force found no new evidence to support routine screening.

12 Apr 2012

ALL induction treatment failure should not be an automatic indication for bone marrow transplant

International study that included St. Jude Children's Research Hospital reports some young acute lymphoblastic leukemia patients who fail induction therapy can achieve high cure rates without bone marrow transplantation.

12 Apr 2012

Consumption of long-chain omega-3 PUFAs lowers risk of colorectal polyps in women

New research finds that omega-3 polyunsaturated fatty acids (PUFAs) found in seafood (long-chain omega-3s) may reduce the risk of precancerous colorectal polyps in women, enhance the muscular benefits of strength training in older women and improve eye health after corneal surgery.

12 Apr 2012

Abnormally low level of SMN protein linked to movement problems in spinal muscular atrophy

An abnormally low level of a protein in certain nerve cells is linked to movement problems that characterize the deadly childhood disorder spinal muscular atrophy, new research in animals suggests.

12 Apr 2012

Online tool can accurately diagnose autism within minutes

Researchers at Harvard Medical School have significantly reduced from hours to minutes the time it takes to accurately detect autism in young children.

12 Apr 2012

Screen time linked with obesity in children

Approximately 20 percent of adolescents in the U.S. today are obese or overweight. With the number of obese and overweight younger children close behind, this epidemic has lasting implications for the future.

12 Apr 2012

Transcription factors do not act like an 'on-off' switch

A UNC-led team of scientists has now shown that transcription factors don't act like an 'on-off' switch, but instead can exhibit much more complex binding behavior.

12 Apr 2012

Botanical formula controls aggressive human prostate tumors in mice

A non-toxic, botanical formula controls aggressive human prostate tumors in mice, according to a peer-reviewed study in the The International Journal of Oncology. Researchers at Indiana University, Methodist Research Institute, showed the prostate formula significantly suppresses tumor growth in aggressive, hormone-refractory (androgen-independent) human prostate cancer cells.

11 Apr 2012

New method for direct identification of antigens

The immune system is a vital part of our defenses against pathogens, but it can also attack host tissues, resulting in autoimmune disease. The antigens that induce destructive immune reactions can now be identified directly - without any prior knowledge of their possible structure.

11 Apr 2012

First large study to examine age, gender and sibling history on stroke risk

If your brother or sister had a stroke, you may be at least 60 percent more likely to have one too, according to research reported in the American Heart Association journal Circulation: Cardiovascular Genetics.

11 Apr 2012

Genes and obesity link found in kids

The team of researchers used genome-wide association techniques and found that several genetic variants associated with adult obesity are also active in childhood obesity, according to Struan Grant of the Children's Hospital of Philadelphia and colleagues. The analysis found two new genetic variants that had not been previously associated with obesity, Grant and colleagues reported online in Nature Genetics. The findings show that “there is indeed a genetic signature of childhood obesity,” Grant said. “It's not purely lifestyle.”

10 Apr 2012

Autism linked to maternal obesity: Study

The study published Monday in the journal Pediatrics shows that compared to non-obese mothers those who were obese before pregnancy had a 1.6 times increase in the likelihood of having a child with autism.

10 Apr 2012

Biovest seeks Health Canada approval of BiovaxID for follicular NHL

Biovest International, Inc., a majority-owned subsidiary of Accentia Biopharmaceuticals, Inc., today announced that Biovest is seeking marketing approval in Canada for BiovaxID, its personalized cancer vaccine for the treatment of follicular non-Hodgkin's lymphoma, an incurable cancer of the immune system.

10 Apr 2012

Two CNVs may increase risk of aggressive prostate cancer

An international research team led by Weill Cornell Medical College investigators have discovered two inherited-genetic deletions in the human genome linked to development of aggressive prostate cancer.

10 Apr 2012

First study to demonstrate link between social status and genetic regulation in primates

The ranking of a monkey within her social environment and the stress accompanying that status dramatically alters the expression of nearly 1,000 genes, a new scientific study reports. The research is the first to demonstrate a link between social status and genetic regulation in primates on a genome-wide scale, revealing a strong, plastic link between social environment and biology.

10 Apr 2012

Study: Body and head lice are the same species

A new study offers compelling genetic evidence that head and body lice are the same species. The finding is of special interest because body lice can transmit deadly bacterial diseases, while head lice do not.

10 Apr 2012

KLF15 gene governs the body's ability to burn fat during exercise

While exercise is accepted universally as the most beneficial prescription physicians can write for patients, little is known about the molecular mechanisms that generate its widespread health benefits. Researchers from Case Western Reserve School of Medicine have shed light on this mystery by discovering that a genetic factor, Kruppel-like Factor 15 (KLF15), governs the body's ability to burn fat during exercise.

10 Apr 2012

Novel anti-leukemia compound with little toxicity successfully treats zebrafish

A novel anti-leukemia compound with little toxicity successfully treated zebrafish with T-cell acute lymphoblastic leukemia (T-ALL), suggesting its potential to become a new highly targeted therapy for humans - even those resistant to conventional therapies - according to results from a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

9 Apr 2012

Delivering chemotherapy drugs with nanobubbles more deadly to cancer cells

Using light-harvesting nanoparticles to convert laser energy into "plasmonic nanobubbles," researchers at Rice University, the University of Texas MD Anderson Cancer Center and Baylor College of Medicine (BCM) are developing new methods to inject drugs and genetic payloads directly into cancer cells.

9 Apr 2012

A step closer to correcting unhealthy gene mutations with diet

Scientists have moved a step closer to correcting some unhealthy gene mutations with diet, according to a new research report appearing in the April 2012 issue of the journal GENETICS.

9 Apr 2012