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Many women near the menopause transition use cannabis, study finds

The legalization of cannabis in many areas has led to its use to treat an array of health issues. Of those surveyed in a study out of the University of Alberta, Edmonton, Canada, one in three women near the menopause transition use cannabis;

22 Sep 2021

At an overrun ICU, ‘the problem is we are running out of hallways’

Nurses fill the hospital room to turn a patient from his stomach to his back. The ventilator forcing air into him is most effective when he's on his stomach, so he is in that position most hours of the day, sedated and paralyzed by drugs.

22 Sep 2021

Revised guidelines perpetuate racial and ethnic disparities in lung cancer screening eligibility

Revised guidelines for lung cancer screening eligibility are perpetuating disparities for racial/ethnic minorities, according to a new study in Radiology.

22 Sep 2021

New framework needed to explore links between evolved pathogen tolerance and emerging infections

A new multidisciplinary research framework is needed to explore links between evolved tolerance to pathogens and their spillover into humans, scientists write today in the journal eLife.

22 Sep 2021

Research highlights potentially life-saving screening for HR-HPV–driven head and neck cancers

Cancer causing high-risk human papillomaviruses (HR-HPV) are responsible for the rising incidence of HR-HPV–driven head and neck cancers (HNC), particularly oropharyngeal cancers (OPC, or throat cancers). Investigators have determined that HR-HPV DNA can be detected in saliva in most patients with HPV-driven OPC at the time of diagnosis. This work highlights a potentially life-saving screening program based on salivary HR-HPV DNA testing for early cancer detection and patient monitoring. Their findings appear in The Journal of Molecular Diagnostics, published by Elsevier.

22 Sep 2021

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Healthy eating pattern improves weight, reduces cardiovascular disease risks in overweight children

A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks.

22 Sep 2021

Children receiving living donor liver transplant less likely to experience organ rejection

In the United States alone, 500 children will need a liver transplant this year. While liver tissue can come from living or deceased donors, no studies have demonstrated which of these methods leads to better outcomes for children. In a new publication, researchers at Children's Hospital Los Angeles pooled published results from over 8,000 pediatric patients across four continents. The data reveal that children who receive living donor liver tissue for transplants are far less likely to experience serious complications like organ rejection.

22 Sep 2021

Study supports the implementation of Beckman Coulter’s MDW in emergency labs as initial test to detect sepsis

Beckman Coulter announced the results of a prospective study carried out across two European hospitals, which found that Monocyte Distribution Width, in combination with White Blood Cell Count with Differential, has the diagnostic accuracy to detect the risk of sepsis and severe infection upon patient presentation in A&E, particularly when assessed in patients with a lower likelihood of sepsis.

22 Sep 2021

Discovery of genes opens the door to new treatments for obesity

Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain.

22 Sep 2021

Scientists use statistical mechanics to make sense of DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Researchers devise guidelines for reporting mediation analyses of trials, observational studies

A new guideline has been developed to help scientists publish their research accurately and transparently. Published in JAMA, the AGReMA Statement (A Guideline for Reporting Mediation Analyses) provides recommendations for researchers who want to describe mediation analysis in their paper. Mediation analysis is primarily used to understand how an intervention works or why it does not.

22 Sep 2021

Cardiothoracic surgeons implant novel type of artificial heart in a female patient

A cardiothoracic surgical team with UofL Health – Jewish Hospital and the University of Louisville has performed the world's first Aeson® bioprosthetic total artificial heart implantation in a female patient. The investigational device, currently intended as a bridge to heart transplant, is part of an Early Feasibility Study (EFS) sponsored by CARMAT, a French medical device company, in partnership with UofL, UofL Health – Jewish Hospital and the UofL Health – Trager Transplant Center.

22 Sep 2021

Medicine News and Research

Many women near the menopause transition use cannabis, study finds

At an overrun ICU, ‘the problem is we are running out of hallways’

Revised guidelines perpetuate racial and ethnic disparities in lung cancer screening eligibility

New framework needed to explore links between evolved pathogen tolerance and emerging infections

Research highlights potentially life-saving screening for HR-HPV–driven head and neck cancers

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Healthy eating pattern improves weight, reduces cardiovascular disease risks in overweight children

Children receiving living donor liver transplant less likely to experience organ rejection

Study supports the implementation of Beckman Coulter’s MDW in emergency labs as initial test to detect sepsis

Discovery of genes opens the door to new treatments for obesity

Scientists use statistical mechanics to make sense of DNA folding

Researchers devise guidelines for reporting mediation analyses of trials, observational studies

Cardiothoracic surgeons implant novel type of artificial heart in a female patient

Artificial intelligence predicts the risk of metastatic relapse in breast cancer patients

Nemours receives $10.5 million NIH grant to support research in sickle cell disease

Clinical trial to test new automatic oxygen control device for premature babies

Delirium is highly likely in patients hospitalized for severe COVID-19

Those undergoing treatment for hematological malignancies show reduced immune response to COVID-19 vaccines

Severe tinnitus following SARS-CoV-2 infection

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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