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Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

8 Jun 2020

Novel compound shows promise for ANCA-associated vasculitis

ANCA-associated vasculitis (AAV) is a systemic disease involving the formation of special autoantibodies (so-called anti-neutrophil cytoplasmic antibodies/ANCA) and vascular inflammation.

8 Jun 2020

Tear-gassing protesters during an infectious outbreak ‘a recipe for disaster’

In nationwide demonstrations sparked by the killing of George Floyd in police custody, protesters have been frequently pepper-sprayed or enveloped in clouds of tear gas.

5 Jun 2020

Perchlorate in drinking water may be more dangerous than previously thought

Sometimes toxins, such as hazardous wastes and industrial byproducts, seep into groundwater, the source of our drinking water.

5 Jun 2020

Nicotine promotes spread of lung cancer cells into the brain, study finds

Researchers at Wake Forest School of Medicine have discovered that nicotine promotes the spread of lung cancer cells into the brain, where they can form deadly metastatic tumors.

4 Jun 2020

Hesperos’ immune system-on-a-chip emulates immune reactions for tissue damage and acute inflammation

Hesperos Inc., pioneers of the Human-on-a-Chip in vitro system, today announced the publication of a new peer-reviewed publication that describes how the company’s technology can be used to investigate immune responses following treatment with biological therapeutics for multi-organ systemic diseases, including cancer, infectious diseases and inflammatory disorders.

4 Jun 2020

Drug Teixobactin shows promise against drug-resistant superbugs

Two well-known superbugs are the gram-positive methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). A new drug Teixobactin has shown promise against these microbes. The study titled, “The Killing Mechanism of Teixobactin against Methicillin-Resistant Staphylococcus aureus: an Untargeted Metabolomics Study,” was published in the latest issue of the journal Therapeutics and Prevention.

4 Jun 2020

‘Terminator’ protein suppresses tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

3 Jun 2020

Bruker introduces breakthrough MALDI-2 source on timsTOF fleX, and further innovations in CCS-enabled 4D proteomics on timsTOF

At the virtual ASMS 2020 Reboot conference, Bruker Corporation today announces a major advance in matrix-assisted laser desorption ionization (MALDI) with the launch of the world’s first commercial MALDI-2 post-ionization (PI) source, which is now available as an option on the timsTOF fleXTM ESI/MALDI mass spectrometer.

From Bruker Daltonics 3 Jun 2020

KinaRx receives SBIR grant to speed up clinical trials for AML and other diseases

Acute myeloid leukemia (AML), an aggressive blood cancer, is one of the most lethal cancers. More than 19,000 new cases are diagnosed a year, and more than 11,000 people a year die from it, according to the American Cancer Society.

3 Jun 2020

Bacteria that live in soil and on people have extensive antibiotic-destroying genes

The latest generation of tetracyclines - a class of powerful, first-line antibiotics - was designed to thwart the two most common ways bacteria resist such drugs.

3 Jun 2020

Gene discovery in fruit flies could lead to treatments for age-related hearing loss

Scientists at UCL have discovered sets of regulatory genes, which are responsible for maintaining healthy hearing. The finding, made in fruit flies, could potentially lead to treatments for age-related hearing loss (ARHL) in humans.

2 Jun 2020

Reducing inflammation improves stroke recovery, may extend window for therapy

Reperfusion therapy, the gold standard for stroke treatment, helps restore blood flow after a stroke caused by a clot, preventing loss of brain tissue. However, only about 10% of stroke patients qualify, in part because of reperfusion therapy's narrow treatment window.

1 Jun 2020

Cone snail insulin research could jumpstart the development of better diabetes treatments

Nearly a century after insulin was discovered, an international team of researchers including University of Utah Health scientists report that they have developed the world's smallest, fully functional version of the hormone, one that combines the potency of human insulin with the fast-acting potential of a venom insulin produced by predatory cone snails.

1 Jun 2020

Findings indicate potential therapeutic interventions for Alzheimer’s and other diseases

A team of scientists from Japan recently achieved more efficient degradation of the human serum albumin protein - an important protein in the blood - via high-intensity infrared irradiation, by attaching a zinc metal complex to the protein.

1 Jun 2020

Temple research suggests new way to prevent abdominal aortic aneurysm therapeutically

The main thoroughfare that carries oxygen-rich blood from the heart to the abdomen is known as the abdominal aorta.

28 May 2020

New project launched to find novel treatments for rare genetic diseases

The University Carlos III Madrid, Almirall, S.A. and the MEDINA Foundation have launched a project to find new treatments for recessive dystrophic epidermolysis bullosa and other genetic diseases caused by nonsense mutations.

28 May 2020

New Thermo Scientific Proteome Discoverer 2.5 software strengthens laboratory workflows

Scientists in the life sciences can now benefit from upgrades to a suite of analytical software solutions with new features designed to enhance productivity, confidence and accuracy in numerous fields, including proteomics, food safety and biotherapeutic drug development.

From Thermo Fisher Scientific Inc. 28 May 2020

New high-resolution mass spectrometer expands the proven Thermo Scientific Orbitrap platform

A new generation, high resolution mass spectrometer (MS) is designed to give proteomics, metabolomics, biopharmaceutical characterization and small-molecule scientists the analytical performance required for research and high-throughput analyses.

From Thermo Fisher Scientific Inc. 28 May 2020

New Orbitrap Exploris 120 mass spectrometer redefines productivity in small molecule applications

Scientists working across small molecule applications require systems that support extensive, in-depth analysis of multiple complex samples, while simultaneously increasing output and decreasing costs.

From Thermo Fisher Scientific Inc. 28 May 2020

Compound News and Research

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Novel compound shows promise for ANCA-associated vasculitis

Tear-gassing protesters during an infectious outbreak ‘a recipe for disaster’

Perchlorate in drinking water may be more dangerous than previously thought

Nicotine promotes spread of lung cancer cells into the brain, study finds

Hesperos’ immune system-on-a-chip emulates immune reactions for tissue damage and acute inflammation

Drug Teixobactin shows promise against drug-resistant superbugs

‘Terminator’ protein suppresses tumorigenesis

Bruker introduces breakthrough MALDI-2 source on timsTOF fleX, and further innovations in CCS-enabled 4D proteomics on timsTOF

KinaRx receives SBIR grant to speed up clinical trials for AML and other diseases

Bacteria that live in soil and on people have extensive antibiotic-destroying genes

Gene discovery in fruit flies could lead to treatments for age-related hearing loss

Reducing inflammation improves stroke recovery, may extend window for therapy

Cone snail insulin research could jumpstart the development of better diabetes treatments

Findings indicate potential therapeutic interventions for Alzheimer’s and other diseases

Temple research suggests new way to prevent abdominal aortic aneurysm therapeutically

New project launched to find novel treatments for rare genetic diseases

New Thermo Scientific Proteome Discoverer 2.5 software strengthens laboratory workflows

New high-resolution mass spectrometer expands the proven Thermo Scientific Orbitrap platform

New Orbitrap Exploris 120 mass spectrometer redefines productivity in small molecule applications

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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