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Early success of shorter tuberculosis treatment in Nigeria could pave the way for nationwide rollout

Early success with Nigeria's implementation of the new and shorter six-month tuberculosis treatment regimen in four states could pave the way for its rollout nationwide, says an expert.

10 Jun 2022

Using artificial intelligence to discover new antivirals against COVID-19 and future pandemics

Research into drugs to treat mosquito-borne flaviviruses such as Zika and dengue as well as COVID-19will benefit from a major funding boost, says a group of international scientists using artificial intelligence to discover new oral antivirals.

10 Jun 2022

Study suggests the gut microbiota may be one of the factors determining the physiological inter-sex differences in pain perception

Researchers investigated whether the gut-brain axis could influence pain thresholds.

10 Jun 2022

The physiological relevance and effects of probable in vivo transformation of CBD to delta9-THC in humans

Researchers reviewed studies on the probable conversion of orally administered cannabidiol (CBD) to delta9-tetrahydrocannabinol (delta9-THC or THC) in humans.

10 Jun 2022

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Each year, dentists in the United States perform more than 15 million root canals on infected teeth, removing the inflamed pulp and filling the emptied canal with inert materials such as rubber and cement. What remains is a mineral shell in place of a living tooth.

9 Jun 2022

Study reveals inaccurate label claims on unregulated CBD products

Researchers determine the CBD content in various products and compare it to their label claims.

8 Jun 2022

Molnupiravir reduces hospitalizations and deaths in at-risk, unvaccinated adults with COVID

In a recent phase III study published in the New England Journal of Medicine, researchers demonstrated that oral molnupiravir was effective in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) therapy among non-vaccinated, non-hospitalized adults at-risk for severe illness.

8 Jun 2022

Gastrointestinal complications caused by SARS-CoV-2

scientists discuss the gastrointestinal complications associated with COVID-19.

7 Jun 2022

Inequalities found in oral anticoagulant prescribing to reduce stroke risk in atrial fibrillation patients

There are racial and socioeconomic inequalities in the prescribing of oral anticoagulants to reduce stroke risk in people with atrial fibrillation, according to a new study conducted in the UK and publishing June 7th in the open-access journal PLOS Medicine by Alyaa Ajabnoor of the University of Manchester, United Kingdom, and colleagues.

7 Jun 2022

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease.

7 Jun 2022

Oral pill taken once a day improves outcomes of patients with myelofibrosis

Momelotinib, an oral pill taken once a day, significantly improved outcomes of patients treated for myelofibrosis (MF), a rare but fatal bone marrow cancer, researchers reported June 7.

7 Jun 2022

De novo-designed mini-protein against SARS-CoV-2

Researchers characterized truncated forms of LCB1, a de novo-designed mini-protein, against SARS-CoV-2.

7 Jun 2022

Etiologies of liver cancer are changing and the prognosis is mixed, study says

The primary causes of liver cancer are well known: viral (hepatitis B and C), alcohol and non-alcoholic steatohepatitis (NASH), a condition in which fat builds up in the liver, resulting in chronic inflammation and damage.

7 Jun 2022

Promising results of combination treatment for acute myeloid leukemia to be presented at ASCO 2022

On Tuesday, June 7, Eunice Wang, MD, Chief of Leukemia at Roswell Park Comprehensive Cancer Center, will present the long-term results of a phase 2 clinical trial combining crenolanib, a second-generation FLT3 inhibitor, with standard intensive chemotherapy for treatment of adults with newly diagnosed FLT3-mutant acute myeloid leukemia (AML).

6 Jun 2022

Monkeypox virus transmission via sexual contact

A new study discusses the transmission of monkeypox through sexual contact.

6 Jun 2022

Link between COVID-19 severity and microbiome of saliva and nasopharynx

In a recent study posted to the bioRxiv* preprint server, researchers profiled the salivary and nasopharyngeal microbiomes of coronavirus disease 2019 (COVID-19) patients and determined the association between the microbiomes and COVID-19 severity.

6 Jun 2022

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

In a study of patients with high-risk renal cell carcinoma, those who took the drug everolimus daily for up to one year after surgery lived longer without their disease returning (recurrence-free survival, or RFS) than those who did not take everolimus, although the results narrowly missed the clinical trial's prespecified level for statistical significance.

4 Jun 2022

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

Nearly 43% of patients with non-small cell lung cancer (NSCLC) whose lung cancers harbored a specific KRAS mutation responded to the experimental drug adagrasib, and the targeted agent also showed activity against lesions in the brain that metastasized from the lung tumors, according to results of a study led by Dana-Farber Cancer Institute investigators.

3 Jun 2022

Women are seldom informed about contraceptive failure following common anesthetic use

Women undergoing operations are not being routinely informed that a common anesthetics may make their contraception less effective, putting them at risk of an unplanned pregnancy, new research being presented at Euroanaesthesia, the annual meeting of the European Society of Anaesthesiology and Intensive Care (ESAIC) in Milan, Italy (4-6 June), suggests.

3 Jun 2022

Contraceptive pills may affect some women’s moods

Finding the right type of contraception is important. Oral contraception – also known as the pill – is the most popular and widely used method. In the June edition of Australian Prescriber, Dr Eveline Mu and Professor Jayashri Kulkarni from the Monash Alfred Psychiatry Research Centre in Melbourne write how contraceptive pills may affect some women’s moods.

3 Jun 2022

Oral News and Research

Early success of shorter tuberculosis treatment in Nigeria could pave the way for nationwide rollout

Using artificial intelligence to discover new antivirals against COVID-19 and future pandemics

Study suggests the gut microbiota may be one of the factors determining the physiological inter-sex differences in pain perception

The physiological relevance and effects of probable in vivo transformation of CBD to delta9-THC in humans

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Study reveals inaccurate label claims on unregulated CBD products

Molnupiravir reduces hospitalizations and deaths in at-risk, unvaccinated adults with COVID

Gastrointestinal complications caused by SARS-CoV-2

Inequalities found in oral anticoagulant prescribing to reduce stroke risk in atrial fibrillation patients

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Oral pill taken once a day improves outcomes of patients with myelofibrosis

De novo-designed mini-protein against SARS-CoV-2

Etiologies of liver cancer are changing and the prognosis is mixed, study says

Promising results of combination treatment for acute myeloid leukemia to be presented at ASCO 2022

Monkeypox virus transmission via sexual contact

Link between COVID-19 severity and microbiome of saliva and nasopharynx

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

Women are seldom informed about contraceptive failure following common anesthetic use

Contraceptive pills may affect some women’s moods

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