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Loyola and Notre Dame researchers report promising new approaches to treating cancer

Promising new approaches to treating cancer were reported during a recent meeting of researchers from Loyola University Chicago and the University of Notre Dame.

12 Nov 2015

Moffitt Cancer Center study finds link between common gene mutations and tumor immune surveillance

Learning if a lung cancer patient has genetic mutations can help oncologists determine the best approach to treatment. There are four gene mutations (KRAS, TP53, STK11, and EGFR) that most commonly occur in lung cancer; however, there are limited effective therapies to target these mutations. With this in mind, Moffitt Cancer Center performed an extensive genetic analysis of lung cancer specimens to unravel how mutations in the two of those genes (TP53 and STK11) contribute to the biology of lung cancer and patient outcomes.

12 Nov 2015

Brain scans may predict possibility of recovering from coma

Brain scans of people in a coma may help predict who will regain consciousness, according to a study published in the November 11, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. The study looked at connections between areas of the brain that play a role in regulating consciousness.

12 Nov 2015

Researchers demonstrate new screening model to identify drug targets for the most lethal strain of malaria

A University of South Florida Center for Global Health & Infectious Diseases Research team has demonstrated a new screening model to classify antimalarial drugs and to identify drug targets for the most lethal strain of malaria, Plasmodium falciparum.

12 Nov 2015

Dartmouth researchers reveal involvement of designer brain receptors in cravings

Dartmouth researchers studying rats have discovered that activation of designer neural receptors can suppress cravings in a brain region involved in triggering those cravings.

12 Nov 2015

New research examines previously unknown secret to DNA repair

Michael Hendzel knows all too well that there is little that people can do to control the stability of their genetic code. But he hopes his latest research will help impact this elusive and crucial aspect of medicine. Published in Nature Cell Biology, this research explores a previously unknown secret to DNA repair.

12 Nov 2015

MD Anderson study reveals why chemotherapy drugs not effective for many pancreatic cancer patients

A study at The University of Texas MD Anderson Cancer Center may explain why chemotherapy drugs such as gemcitabine are not effective for many pancreatic cancer patients, and perhaps point to new approaches to treatment including enhancing gemcitabine's ability to stop tumor growth.

12 Nov 2015

Crucial change in single DNA base predisposes children to aggressive form of cancer

Pediatric oncology researchers have pinpointed a crucial change in a single DNA base that both predisposes children to an aggressive form of the childhood cancer neuroblastoma and makes the disease progress once tumors form.

12 Nov 2015

MedTechSouthEast competition displays advanced medical technologies for Parkinson’s patients

Laser-emitting shoes and a Meccano-style walking aid kit are just two of the inventions being developed by companies in London and the south east that could help people stay independent for longer as they get older or develop debilitating illnesses, according to Design Council and MedCity, the Mayor of London’s life sciences promotional organisation.

12 Nov 2015

Study shows rare HER2 missense mutations do not spread breast cancer on their own

Results of a new laboratory study by Johns Hopkins Kimmel Cancer Center researchers suggests that some rare “missense” mutations in the HER2 gene are apparently not — on their own — capable of causing breast cancer growth or spread.

12 Nov 2015

Montefiore and Einstein researchers awarded $14 million PCORI grant for hepatitis C research

A research team at Montefiore Health System and Albert Einstein College of Medicine led by Alain Litwin, M.D., was awarded $14 million by the Patient-Centered Outcomes Research Institute (PCORI) to determine how best to treat hepatitis C among people who inject drugs (PWID), a group with a high rate of infection.

11 Nov 2015

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease.

11 Nov 2015

Tocilizumab drug offers potential treatment for patients with polymyalgia rheumatics

A drug approved to treat rheumatoid arthritis, tocilizumab (Actemra, Genentech), is a potential new therapy for patients with polymyalgia rheumatica, according to an open-label, phase II study presented at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals on November 10.

11 Nov 2015

Medicines do not degrade after being stored in space, shows study

The results of an opportunistic, pilot-scale study led by Virginia Wotring of the Center for Space Medicine and Department of Pharmacology at Baylor College of Medicine in the US suggest that medication degradation on the International Space Station (ISS) does not differ from what is typically seen on Earth.

11 Nov 2015

Florida Institute finalizes funding agreement with Genetic Networks

The Florida Institute for the Commercialization of Public Research (the Institute) announced today that it has finalized a funding agreement with Genetic Networks, a Miami based company with technology developed at the University of Miami.

11 Nov 2015

Small behavioral changes can improve heart health

Improving your heart health may be as simple as making small behavioral changes - a new study of behavioral health interventions suggests that they are effective at helping people alter their lifestyles and lead to physical changes that could improve overall health.

11 Nov 2015

Cotellic (cobimetinib) approved to be used in combination with vemurafenib for melanoma treatment

The U.S. Food and Drug Administration today approved Cotellic (cobimetinib) to be used in combination with vemurafenib to treat advanced melanoma that has spread to other parts of the body or can't be removed by surgery, and that has a certain type of abnormal gene (BRAF V600E or V600K mutation).

10 Nov 2015

White coat hypertension, masked hypertension increase cardiovascular events over the years

Patients whose blood pressures spikes in the doctor's office but not at home, and patients whose blood pressure spikes at home but not in the doctor's office, suffer more heart attacks, heart failure, and strokes than patients with normal blood pressures in both settings, UT Southwestern Medical Center researchers have found.

10 Nov 2015

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

New Haven Pharmaceuticals, Inc. today announced new study data that shows the company's FDA-approved drug DURLAZA delivers sustained antiplatelet control for a full 24-hour period in high-risk patients.

10 Nov 2015

SKYGEN USA announces launch of Hylis Pharmacy Solutions

Citing a need to bring skyrocketing pharmacy costs under control, SKYGEN USA, the umbrella brand for a distinguished family of benefit management companies and technology solutions for health payers and healthcare organizations, today announced the launch of Hylis Pharmacy Solutions.

10 Nov 2015

Drugs News and Research

Loyola and Notre Dame researchers report promising new approaches to treating cancer

Moffitt Cancer Center study finds link between common gene mutations and tumor immune surveillance

Brain scans may predict possibility of recovering from coma

Researchers demonstrate new screening model to identify drug targets for the most lethal strain of malaria

Dartmouth researchers reveal involvement of designer brain receptors in cravings

New research examines previously unknown secret to DNA repair

MD Anderson study reveals why chemotherapy drugs not effective for many pancreatic cancer patients

Crucial change in single DNA base predisposes children to aggressive form of cancer

MedTechSouthEast competition displays advanced medical technologies for Parkinson’s patients

Study shows rare HER2 missense mutations do not spread breast cancer on their own

Montefiore and Einstein researchers awarded $14 million PCORI grant for hepatitis C research

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Tocilizumab drug offers potential treatment for patients with polymyalgia rheumatics

Medicines do not degrade after being stored in space, shows study

Florida Institute finalizes funding agreement with Genetic Networks

Small behavioral changes can improve heart health

Cotellic (cobimetinib) approved to be used in combination with vemurafenib for melanoma treatment

White coat hypertension, masked hypertension increase cardiovascular events over the years

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

SKYGEN USA announces launch of Hylis Pharmacy Solutions

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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